Lab Outings
Homologous Recombination
RNAi off-Target Effects
Ravi D, Wiles AM, Bhavani S, Ruan J, Leder P, Bishop AJ.
PLoS Genet. 2009 Jun;5(6):e1000527. Epub 2009 Jun 19.
PMID: 19543366 [PubMed - in process]
Wiles, A.M, Ravi, D., Bhavani, S., Bishop, A.J.R. “An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme. ” J Biomol Screen. 2008 Sep;13(8):777-84. Epub 2008 Aug 27
Reliene R, Bishop AJR, Schiestl RH. Involvement of homologous recombination in carcinogenesis. Adv. Genet. 2007;58:67-87.
Leder A, McMenamin J, Fontaine K, Bishop AJR and Leder P. (2005) “ ζ -/- thalassemic mice are affected by two modifying loci and display unanticipated somatic recombination leading to inherited variation.” Human Molecular Genetics 14(5):615-625
Bishop AJR, Hollander MC, Fornace J, Sidman RL, and Schiestl RH.“p21 controls patterning but not homologous recombination in RPE development” DNA Repair (Amst). 2006. Jan 5:5(1):111-20
Secretan, M.B., Scuric, Z., Oshima, J., Bishop, A.J.R., Howlett, N.G., Yau, D., and Schiestl, R.H. (2004). “Effect of Ku86b and DNA-PKcs Deficiency on Non-homologous End-Joining and Homologous Recombination Using a Novel Transient Screening Assay.” Mutation Research, 554: 351-364.
Reliene, R., Bishop, A.J.R., Li, Gloria and Schiestl, R.H. (2004). “Ku86 involved in intrachromosomal homologous recombination in vivo in mice”. DNA Repair. 3:103-111 .
Bishop, A.J.R. , Hollander, M.C., Kosaras, B., Sidman, R.L., Fornace, A. and Schiestl, R.H. (2003). “Atm, P53 and Gadd45a deficient mice have an increased frequency of homologous recombination at different times during development.” Cancer Research 63:5335-5343.
Bishop, A.J.R. and Leder, P. (2002). “Genetic interaction between the unstable v-Ha-Ras transgene (Tg.AC) and the murine Werner syndrome gene: Transgene instability and tumorigenesis.”Oncogene. 21(43):6657-6668
Bishop, A.J.R. , Kosaras, B., Carls, N., Sidman, R., and Schiestl, R.H. (2001). “Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice.” Carcinogenesis. 22(4):641-649
Bishop, A.J.R. , Kosaras, B., Sidman, R., and Schiestl, R.H. (2000). “Benzo(a)pyrene and X-rays induce reversion of the pink-eyed unstable mutation in the retinal pigment epithelium of mice.” Mutation Research. 457:31-40.
Bishop, A.J.R. , Barlow, C., Wynshaw-Boris, A. J., Schiestl, R.H. (2000). "ATM deficiency causes an increased frequency of intrachromosomal homologous recombination in mice.” Cancer Research. 60:395-399
Aubrecht, J., Secretan, M.B., Bishop, A.J.R., Schiestl, R.H. (1999). “Involvement of p53 in X-ray induced intrachromosomal recombination in mice.” Carcinogenesis. 20:2229-2236
Bishop, A.J.R. , Louis, E.J., and Borts, R.H. (2000). “Generating minisatellite variants in yeast: DNA removal during meiotic gene conversion.”Genetics. 156:7-20
Select Reviews
Ravi D and Bishop AJR. RNA interference and functional genomics: From genes to drug discovery. Icfai Journal of Biotechnology, 2008, 2(3)
52-62
Brown AD, Karia B, Wiles AM and Bishop AJR. The intertwining of DNA damage response pathway components and homologous recombination repair. Genetic Recombination Research Progress, 2008; 1-68.
Reliene, R., Bishop, A.J.R., Aubrecht, J., and Schiestl, R.H. (2004) “In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer.”Methods, Molecular Biology, Recombination Protocols. 262:125-139
Bishop, A.J.R. and Schiestl, R.H. “Role of homologous recombination in carcinogenesis.” (2003) Experimental and Molecular Pathology.
74(2):94-105
Bishop, A.J.R. and Schiestl, R.H. (2002). “Homologous recombination and its role in carcinogenesis.” Journal of Biotechnology and Biomedicine. 2(2):75-85
Bishop, A.J.R. and Schiestl, R.H. (2001). “Homologous recombination and its role in carcinogenesis”. Biochemica et Biophysica ACTA" – Reviews on Cancer. 147(3):109-121
Bishop, A.J.R . and Schiestl, R.H. (2000). “Homologous recombination as a mechanism for genome rearrangements: environmental and genetic effects.” Human Molecular Genetics. 9(16):2427-2434