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Publications by Dr. Keller

Paul McDonald, Shoukat Dedhar and Charles Keller.  Two sides of an Oncoprotein: the different biologies of Integrin-Linked kinase in Rhabdomyosarcoma subtypes. (CommentaryThe Journal of Clinical Investigation, in press

 

Koichi Nishijo, Tohru Hosoyama, Christopher R.R. Bjornson, Beverly Schaffer, Ali N. Bahadur, Mark S. Hansen, Mary C. Blandford, Amanda T. McCleish, Brian P. Rubin, Jonathan A. Epstein, Thomas A. Rando, Mario R. Capecchi, Charles Keller.  Biomarker System for studying muscle, stem cells and cancer in vivo.  The FASEB Journal, epub ahead of print(April 2009) [Pubmed UID 19332644 ]

 

Koichi Nishijo, Qing-Rong Chen, Lei Zhang, Amanda T. McCleish, Andrea Rodriguez, Min Jung Cho, Suresh I. Prajapati, Jonathan A. L. Gelfond, Gary B. Chisholm, Joel E. Michalek, Bruce J. Aronow, Frederic G. Barr, R. Lor Randall, Marc Ladanyi, Stephen J. Qualman, Brian P. Rubin, Robin D. LeGallo, Chiayeng Wang, Javed Khan, Charles Keller.  Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma. Cancer Research, 69(7): 2902-2911, April 2009 [ Research Highlights ] [Pubmed UID 19339268]

 

Eri Taniguchi, Omar J. Rivera, Amanda T. McCleish, Min Jung Cho, Benjamin R. Arenkiel, Stephen J. Qualman, Matthew P. Scott, Mario R. Capecchi, Charles Keller.  Bortezomib Reverses a Post-Translational Mechanism of Tumorigenesis for Patched1 Haploinsufficiency in Medulloblastoma, Pediatric Blood & Cancer, 2009 Feb 11 epub ahead of print [Pubmed UID 19213072]

 

Suresh I Prajapati, Carlo O Martinez, Ali N Bahadur, Isabel Q Wu,Wei Zheng, James D Lechleiter, Linda M McManus, Gary B Chisholm, Joel E Michalek, Paula K Shireman, Charles Keller.  A Novel Near-Infrared Contrast Agent for Injured Tissue in Living Subjects. Molecular Imaging, February 2009, 8(1):45-54[COVER ARTICLE] [Pubmed UID 19344575]

 

Eri Taniguchi, Koichi Nishijo, Amanda T. McCleish, Joel E. Michalek, Robin D. Legallo, Stephen J. Qualman, Hanna E. Abboud, Brian P. Rubin, Charles Keller.  PDGFR-A is a Therapeutic Target in Alveolar Rhabdomyosarcoma.  Oncogene, 2008, Nov 20;27(51):6550-60 [PubMed UID 18679424] ePub August 4, 2008

 

 Sergio X. Vasquez, Mark S. Hansen, Ali N. Bahadur, Matthew F. Hockin, Gordon L. Kindlmann, Lisa Nevell, Isabel Q. Wu, David J. Grunwald, David M. Weinstein, Greg M. Jones, Christopher R. Johnson, John L. VandeBerg, Mario R. Capecchi, Charles Keller.  Optimization of Volumetric Computed Tomography for Skeletal Analysis of Model Genetic Organisms, The Anatomical Record, 291(5), 475-487 [COVER ARTICLE] [PubMed UID 18286615]

 

Andrew S. Brack, Michael J. Conboy, Mark Lee, Sudeep Roy, Calvin J. Kuo, Charles Keller, Thomas A. Rando. “Elevated Wnt signaling during aging alters the fate of myogenic stem cells leading to increased fibrosis and impaired muscle regeneration,” Science, 2007 August; 317:807-810 [PubMed UID 17690295]

 

 Ali N. Bahadur, Isabel Q. Wu, David M. Weinstein, M. Duff Davis, David A. Lewis, Peter Kochunov, Charles Keller.  “Multimodality Chamber for coregistered anatomical and molecular imaging of small animals,” Lab Animal.2007 September, 36(8): 29-35 [COVER ARTICLE] [PubMed UID 17721530]

 

John T. Johnson, Mark S. Hansen, Isabel Wu, Lindsey J. Healy, Christopher R. Johnson, Greg M. Jones, Mario R. Capecchi, Charles Keller.  “Virtual Histology of Transgenic Mouse Embryos for High-Throughput Phenotyping,PLoS Genetics, 2006, 2(4)e61 [COVER ARTICLE] [PubMed UID 16683035]

 

Mary Blandford, Frederic G. Barr, James C. Lynch, R. Lor Randall, Stephen J. Qualman, Charles Keller. “Rhabdomyosarcomas Utilize Developmental Myogenic Growth Factors for Disease Advantage,” Pediatric Blood & Cancer, 2006 Mar; 46(3):329-38 [PubMed UID 16261596]

 

Gordon L. Kindlmann, David M. Weinstein, Greg M. Jones, Christopher R. Johnson, Mario R. Capecchi, Charles Keller.  “Practical Vessel Imaging by Computed Tomography in Live Transgenic Mouse Models for Human Tumors,” Molecular Imaging, 2005 Oct;4(4):417-24 [PubMed UID 16285903]

 

Charles Keller, Mario R. Capecchi. “New Genetic Tactics to Model Alveolar Rhabdomyosarcoma in the Mouse,” Cancer Research, 65(17):7530-2, September 2005 [PubMed UID 16140913]

Featured in Dr. Capecchi’s Nobel Lecture, http://nobelprize.org/mediaplayer/index.php?id=771

 

Charles Keller, Ben Arenkiel, Nabeel El-Bardeesy, Cheryl Coffin, Ronald DePinho, Mario Capecchi.  “Alveolar Rhabdomyosarcomas in Conditional Pax3:Fkhr Mice: Cooperativity of Ink4a/ARF and Trp53 Loss of Function,” Genes & Development, 18(21) 2614-26, November 2004 [PubMed UID 15489287]

 

Charles Keller, Mark S. Hansen, Cheryl Coffin, Mario Capecchi.  "Pax3:Fkhr interferes with Embryonic Pax3 and Pax7 Function: Implications for Alveolar Rhabdomyosarcoma Cell of Origin,” Genes & Development, 18(21) 2608-13, November 2004 [PubMed UID 15520281]