Argonne National Laboratory: Hide and Seek: Understanding How COVID-19 Evades Detection in a Human Cell (Gupta)
November 3, 2020
BY ANDRE SALLES |OCTOBER 29, 2020 Scientists using the Advanced Photon Source have discovered new insights into the ways the SARS-CoV-2 virus camouflages itself inside the human body. Scientists around the world have been working for months to identify and develop treatments that combat SARS-CoV-2, the virus that causes COVID-19. An important part of that process […]
ECancer Interview: Prospective validation of single mouse testing by the paediatric preclinical testing consortium (Houghton)
October 24, 2020
Dr. Peter Houghton speaks to ecancer about the prospective validation of single mouse testing by the pediatric preclinical testing consortium; a study that was presented at ENA 2020 this year. Dr. Houghton initially explains the rationale behind this study and talks about how it was tested that using a single mouse for studying drug efficacy […]
Cardiovascular Business: Chemotherapy could be damaging children’s heart cells, leading to problems later in life (Aune)
September 30, 2020
Undergoing chemotherapy can have a negative impact on the cells responsible for repairing heart damage, according to a new study published in PLOS One. This may explain why 20% of children treated with anthracyclines go on to experience heart failure later in life. “We don’t fully understand why some children who are exposed to anthracycline therapy […]
August 20, 2020
PROJECT SUMMARY Glioblastoma (GBM) is the most common and most aggressive brain tumor type among adults with a 14 months average patient survival. Despite all genomic efforts in recent years, novel therapies based on GBM common mutations and alterations have been disappointing. To build an alternative route, we have been focusing on oncogenic RNA binding […]
August 20, 2020
PI: Leonidas Bleris, PhD Co-PI: Alexander Pertsemlidis, PhD (UT Dallas) (UT Health San Antonio) PROJECT SUMMARY Collaborative Research: Unraveling extracellular microRNA communication Overview: […]
Physician’s Weekly: PCAT: an integrated portal for genomic and preclinical testing data of pediatric cancer patient-derived xenograft models.
August 20, 2020
Although cancer is the leading cause of disease-related mortality in children, the relative rarity of pediatric cancers poses a significant challenge for developing novel therapeutics to further improve prognosis. Patient-derived xenograft (PDX) models, which are usually developed from high-risk tumors, are a useful platform to study molecular driver events, identify biomarkers and prioritize therapeutic agents.
August 11, 2020
Congratulations to one of our CSA graduate students Pooja Yadav, M.S. (Cancer Biology discipline) who successfully defended her PhD dissertation on June 25!
August 5, 2020
Like a thief in the night, Covid-19 can disguise itself to easily enter and infect cells in the human body. A new research study details what cells are more susceptible to the coronavirus. SARS-CoV-2 can mimic the proteins of a human cell to evade detection by the immune system. Once inside the cell, it can […]
UNITED PRESS INTERNATIONAL – Researchers identify enzyme that helps COVID-19 evade immune system (Gupta Lab)
July 30, 2020
Researchers announced Friday that they have discovered an enzyme that helps COVID-19 enter cells in the human body, allowing the infection to grow. Called non-structural protein 16, or nsp16, the enzyme is produced by the new coronavirus and acts as a “camouflage,” tricking human cells into thinking that the virus is “part of its own code and […]
July 28, 2020
SARS-CoV-2, the coronavirus that causes COVID-19, has been labeled with a variety of different adjectives over the past few months. Deadly, awful, and evil, just to name a few. Now, according to a new study from the University of Texas Health Science Center San Antonio, another descriptor can be added to the coronavirus’ modus operandi: deceitful.