Greehey CCRI Seminar Series: Min Kyu Kim, PhD, MS (UTHSA, Biochemistry & Structural Biology)
Presentation title: TBD
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Presentation title: TBD
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Subspecialties:Large-scale Quantitative Proteomics; DNA Damage Response and DNA Repair Mechanisms; Cancer Systems and Protein interaction Network Biology
I am interested in profiling protein-protein interactions and post-translational modifications of proteins governing pathway deregulation in cancer and other human diseases using cutting-edge mass spectrometry-based proteomics. Particularly, my laboratory is studying how protein-protein interactions and various cellular signaling cascades (including phosphorylation, ubiquitylation, and methylation) regulate genome integrity during cellular DNA damage response. Given that many types of human cancer are caused by defects in executing DNA damage repair identifying novel interaction partners and regulatory cues of DNA repair proteins will enable us to pinpoint novel cancer-associated genes and therapeutic vulnerabilities of cancer cells that could be targeted in the clinic for precision oncology.
Learn more about Dr. Kim’s research.
Greehey CCRI Host: Yogesh Gupta, PhD