Greehey CCRI ZOOMinar Series Presents: Vladimir Uversky, PhD, DSc– Univ of South Florida
Event Date & TimeApril 30, 2021 at 11:00 am - 12 noon
LocationZoom Meeting ID: 966 9324 0180 Passcode: Seminar21!
Presentation Title: "Unusual Biophysics and Strange Biology of Intrinsic Disorder"
Greehey CCRI Host: David Libich, PhD.
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About the Speaker(s)
Our scientific interests are broadly defined as everything related to protein folding, misfolding, and non-folding. However, the passion is definitely the field of protein non-folding, which is related to the discovery of intrinsically disordered proteins (IDPs), analysis of their abundance in nature, characterization of their exceptional structural and functional plasticity, understanding of their vital roles in various biological processes, and establishing their involvement in the pathogenesis of multiple human diseases. These and related aspects of IDPs are analyzed by a combination of a wide spectrum of computational, bioinformatics, and experimental approaches of modern protein biophysics. Due to the high abundance of IDPs in various proteomes, the exceptional structural and functional plasticity of these proteins, and their intimate relations to the maladies' pathogenesis, it is almost impossible to find an area of protein science where IDPs would not play a noticeable role.