Greehey CCRI Seminar Series, Fall ’23: Ludmil B. Alexandrov, PhD, Moores Cancer Center, UCSD

My research has been focused on understanding mutational processes in human cancer through the use of mutational signatures. In 2013, I developed the first comprehensive map of the signatures of the mutational processes that cause somatic mutations in human cancer. This work was published in several well-regarded scientific journals and highlighted by the American Society of Clinical Oncology as a milestone in the fight against cancer. More recently, I mapped the signatures of the clock-like mutational processes operative in normal somatic cells, demonstrated that mutational signatures have the potential to be used for targeted cancer therapy, and identified the mutational signatures associated with tobacco smoking. My interests, expertise, and interpersonal skills are backed up by more than 100 scientific publications, prestigious national and international awards, as well as work experience in government laboratories, renowned universities, and leading consulting companies.

During the past few years, I have received multiple awards for my work on mutational signatures in human cancer. Most recently, I was awarded a 2020 NIEHS Outstanding New Environmental Scientist Award.

Learn more about Dr. Alexandrov.