Greehey CCRI Seminar Series, Spring ’23: Ricardo Aguiar, M.D., Ph.D. – UT Health San Antonio
Event Date & TimeJune 2, 2023 at 12:00N -1:00P
LocationGreehey CCRI Auditorium (2.160)
Presentation title: TBD
Greehey CCRI Host: Alexander J. R. Bishop, D.Phil
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About the Speaker(s)
Our group focus is on the identification and functional characterization of the genetic abnormalities of hematologic malignancies. We utilize in vitro and in vivo systems in genome-wide or targeted studies to translate these discoveries into clinical initiatives. The principal disease model in our lab is B-cell lymphoma. Active research lines stem from our recently published work and include: 1) The intersection between B-cell receptor signaling and phosphodiesterase 4 (PDE4) as actionable therapeutic targets in mature B cell malignancies; 2) Metabolic imbalance and epigenetic reprogramming in lymphomas; 3) Transcription factor IRF8 and lymphomagenesis.