microRNA expression and dissemination in the progression of Alzheimer’s Disease

Funding Agency: National Institute on Aging/San Antonio Nathan Shock Center

Title: microRNA expression and dissemination in the progression of Alzheimer’s Disease

Status: Active

Period: 01/01/2017-12/31/2017

Role: Principal Investigator

Grant Detail: To test the hypothesis that inter-cellular communication between glial cells and neurons, specifically mediated by transfer of miRNAs through gap junctions, contributes to the propagation of AD pathology through activation of gamma secretase and APP cleavage