Postdoctoral Scientist Computational Pharmacogenomics (Zheng Lab)

Job Description

We (Zheng Lab) are seeking a highly motivated postdoctoral scientist to lead a computational pharmacogenomics project. The goal of the project is to characterize tumor responses to therapeutics in childhood cancers. To do so, the candidate will mine genomic and pharmacological data of patient-derived xenograft models and will lead the analysis of single-cell RNA sequencing data.

The candidate is expected to work closely with the PI and collaborators. Qualifications of the candidate include training in bioinformatics, computational biology, or a related discipline; proficient use of a programing language and the Linux environment; and a first-author publication in a peer-reviewed journal. Training and experience in cancer biology are welcome but not required. Candidates with good communication skills are preferred.

Responsibilities include data analysis, algorithm design, report, and manuscript preparation. The candidate will receive committed supervision from the PI but is expected to grow independence gradually. In our lab, we value career development for our trainees. The PI is committed to supporting trainees for competing for fellowships, high-profile publications, and academic awards.

Our lab is located at Greehey Children’s Cancer Research Institute (GCCRI), University of Texas Health San Antonio. The lab currently has four postdoctoral scientists from multiple cultural backgrounds. GCCRI is housed in a state-of-the-art 100,000 sq. ft. building and is the largest free-standing childhood cancer research facility in Texas, USA. The building is home to the genome sequencing facility, siRNA/CRISPR screening facility, bioinformatics core, and 17 research labs. These labs work on different aspects of childhood cancer and are highly synergized. Such synergy leads to abundant collaborations and an intellectually stimulating academic environment.

Salary & Benefits

The salary starts at $53,760 and is negotiable with the candidate’s experience. We provide full retirement benefits and outstanding health insurance at the UT system.

UT Health San Antonio is one component of the 14 institutions comprising The University of Texas System and is the largest university health science center in South Texas.  Formerly known as the Cancer Therapy & Research Center, the UT Health Cancer Center is one of only four National Cancer Institute-designated cancer centers in Texas.  The Greehey CCRI is dedicated to developing more effective and less toxic therapies for children afflicted by cancer.

Situated at the edge of the Texas Hill Country, San Antonio is the nation’s seventh-largest city and offers a rich, multi-cultural community with a thriving bioscience industry.

All Postdoctoral appointments are designated as security-sensitive positions.  The University of Texas Health Science Center at San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.

How to Apply

Interested candidates should email their cover letter describing past research experience/skills and future research interests/plans, curriculum vitae, and the contact information of three references to Dr. Siyuan Zheng.



Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas — research, clinical, and education.

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