Greehey CCRI News & Events Archive

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Cell: Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities

May 2, 2019

Author links open overlay panelSuhasVasaikar1214ChenHuang1214XiaojingWang121214Vladislav A.Petyuk314Sara R.Savage414BoWen12YongchaoDou12YunZhang1ZhiaoShi12Osama A.Arshad3Marina A.Gritsenko3Lisa J.Zimmerman5Jason E.McDermott3Therese R.Clauss3Ronald J.Mo …


Molecular Cancer Therapeutics: Prospective Clinical Sequencing of Adult Glioma

May 1, 2019

Siyuan Zheng, Kristin Alfaro-Munoz, Wei Wei, Xiaojing Wang, Fang Wang, Agda Karina Eterovic, Kenna R Mills Shaw, Funda Meric-Bernstam, Gregory N Fuller, Ken Chen, Roel G Verhaak, Gordon B Mills, WK Alfred Yung, Shiao-Pei Weathers, John F de Groot Malig …


Molecular Cancer Therapeutics: Prospective Clinical Sequencing of Adult Glioma

May 1, 2019

Siyuan Zheng 1 2 3, Kristin Alfaro-Munoz 4, Wei Wei 5, Xiaojing Wang 3, Fang Wang 6, Agda Karina Eterovic 7, Kenna R Mills Shaw 7, Funda Meric-Bernstam 7, Gregory N Fuller 8, Ken Chen 6, Roel G Verhaak 4 2 6 9, Gordon B Mills 7, W K Alfred Yung 4, Shia …


Clinical Cancer Research: Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models

April 25, 2019

Caitlin D Lowery 1, Michele Dowless 1, Matthew Renschler 1, Wayne Blosser 1, Alle B VanWye 1, Jennifer R Stephens 1, Philip W Iversen 1, Aimee Bence Lin 1, Richard P Beckmann 1, Kateryna Krytska 2, Kristina A Cole 2, John M Maris 2, Douglas S Hawkins 3 …


Pediatric Blood & Cancer: Preclinical activity of the antibody‐drug conjugate denintuzumab mafodotin (SGN‐CD19A) against pediatric acute lymphoblastic leukemia xenografts

April 23, 2019

Luke Jones, Hannah McCalmont, Kathryn Evans, Chelsea Mayoh, Raushan T. Kurmasheva, Catherine A. Billups, Peter J. Houghton, Malcolm A. Smith,  Richard B. Lock Abstract Background Denintuzumab mafodotin (SGN‐CD19A) is a CD19‐targeting antibody‐drug conj …


Nature: More and more people are living for years after treatment. Researchers should look for ways to identify and ease long-term effects.

April 19, 2019

When Gregory Aune was 16, he wasn’t particularly concerned about the lasting effects of the drugs and radiation that he was given to treat his lymphoma. “I saw kids around me die, so I felt pretty fortunate,” he says. Nearly 30 years later, Aune has a …


RNA: Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development

April 19, 2019

Mitzli X Velasco, Adam Kosti, Gabriela DA Guardia, Marcia C Santos, Allison Tegge, Mei Qiao, Bruna RS Correa, Greco Hernández, Erzsebet Kokovay, Pedro AF Galante, Luiz OF Penalva Abstract RNA-binding proteins (RBPs) and miRNAs are critical gene express …


Journal of Virology: Adaptation of an R5 Simian-Human Immunodeficiency Virus Encoding an HIV Clade A Envelope with or without Ablation of Adaptive Host Immunity: Differential Selection of Viral Mutants

April 17, 2019

Mingkui Zhou, Michael Humbert, Muhammad M. Mukhtar, Hanna B. Scinto, Hemant K. Vyas, Samir K. Lakhashe, Siddappa N. Byrareddy, Gregor Maurer, Swati Thorat, Joshua Owuor, Zhao Lai, Yidong Chen, Anthony Griffiths, Agnès-Laurence Chenine, Sanjeev Gumber,  …


Pediatric Blood & Cancer: Characterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation

April 11, 2019

Katherine Haines 1, Stephen F Sarabia 2 3, Karla R Alvarez 2 3, Gail Tomlinson 4, Sanjeev A Vasudevan 3 5, Andras A Heczey 3 6, Angshumoy Roy 2 3, Milton J Finegold 2, D Williams Parsons 1 3 6, Sharon E Plon 1 3 6, Dolores López-Terrada 2 3 Abstract Ba …


Nature: Study cancer survivors

April 9, 2019

More and more people are living for years after treatment. Researchers should look for ways to identify and ease long-term effects. When Gregory Aune was 16, he wasn’t particularly concerned about the lasting effects of the drugs and radiation that he …


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