Greehey CCRI News & Events Archive

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The Journal of Clinical Endocrinology & Metabolism: Synonymous but Not Silent: A Synonymous VHL Variant in Exon 2 Confers Susceptibility to Familial Pheochromocytoma and von Hippel-Lindau Disease

April 9, 2019

Shahida K Flores, Ziming Cheng, Angela M Jasper, Keiko Natori, Takahiro Okamoto, Akiyo Tanabe, Koro Gotoh, Hirotaka Shibata, Akihiro Sakurai, Takuya Nakai, Xiaojing Wang, Magnus Zethoven, Shiva Balachander, Yuichi Aita, William Young, Jr., Siyuan Zheng …

Journal of Trauma and Acute Care Surgery: A prospective study in severely injured patients reveals an altered gut microbiome is associated with transfusion volume

April 1, 2019

Susannah E Nicholson 1, David M Burmeister, Taylor R Johnson, Yi Zou, Zhao Lai, Shannon Scroggins, Mark DeRosa, Rachelle B Jonas, Daniel R Merrill, Caroline Zhu, Larry M Newton, Ronald M Stewart, Martin G Schwacha, Donald H Jenkins, Brian J Eastridge A …

Science Magazine: Treatments for childhood cancer can devastate lives years later. Scientists are trying to change that. (Aune Lab)

March 29, 2019

Greehey CCRI Principal Investigator, Gregory J. Aune, MD, PhD, was quoted in a recent Science Magazine article regarding the long-term effects of childhood cancer treatments.

Investigative & Clinical Urology: Microbiome diversity in carriers of fluoroquinolone resistant Escherichia coli

March 1, 2019

Michael A Liss 1 2, Robin J Leach 1 3, Elizabeth Rourke 1, Allison Sherrill 1, Teresa Johnson-Pais 1 3, Zhao Lai 4, Joseph Basler 1, James R White 5, Jan E Patterson 6 Abstract Purpose: Fluoroquinolone-resistant (FQR) Escherichia coli causes transrecta …

Genome Research: PepQuery enables fast, accurate, and convenient proteomic validation of novel genomic alterations

March 1, 2019

Bo Wen, Xiaojing Wang, Bing Zhang Massively parallel or second-generation sequencing-based genomic studies continuously identify new genomic alterations that may lead to novel protein sequences, which are attractive candidates for disease biomarkers an …

AHA Research – Circulation Research: Abstract 112: Doxorubicin Alters Cardiac Fibroblast Phenotype

February 28, 2019

Trevi R Mancilla, and Gregory J Aune Abstract The oldest cohort of childhood cancer survivors is entering into their sixth decade. The milestone comes with the knowledge that this population is at 15 times greater risk of cardiovascular events than the …

UT Health SA Newsroom: Greehey researcher receives UT System’s Rising STARs award

February 26, 2019

Siyuan Zheng, PhD, assistant professor in the Department of Epidemiology and Biostatistics in the Long School of Medicine, has received a Rising STARs Award from the UT System. The award for early-career investigators comes with a $250,000 grant.

PNAS: Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR

February 26, 2019

Samuel A. Kotler, Vitali Tugarinov, Thomas Schmidt, Alberto Ceccon, David S. Libich, Rodolfo Ghirlando, Charles D. Schwieters, and G. Marius Clore Abstract The N-terminal region of the huntingtin protein, encoded by exon-1, comprises an amphiphilic dom …

Pharmacy Times: Chemotherapies May Have Varying Long-Term Cardiovascular Risk

February 6, 2019

By studying the outcomes of more than 28,000 long-term childhood cancer survivors in the United States and Europe, researchers found that exposure to different anthracyclines results in variable long-term cardiovascular risk.

BMC Genomics: CeL-ID: cell line identification using RNA-seq data

February 4, 2019

Tabrez A. Mohammad, Yun S. Tsai, Safwa Ameer, Hung-I Harry Chen, Yu-Chiao Chiu & Yidong Chen Abstract Background Cell lines form the cornerstone of cell-based experimentation studies into understanding the underlying mechanisms of normal and diseas …

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