Greehey CCRI Archives

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Leibert Pub: Zebrafish Tumor Graft Transplantation to Grow Tumors In Vivo That Engraft Poorly as Single Cell Suspensions (Ignatius Lab)

May 21, 2021

Amanda Lipsitt, Nicole R. Hensch, Rodrigo Moreno-Campos, Kunal Baxi, Jiangfei Chen, Anil K. Challa, Eleanor Y. Chen, and Myron S. Ignatius Abstract Angiosarcoma is a clinically aggressive tumor with a high rate of mortality. It can arise in vascular or …


NIH Grant Awarded to Collaborative Team to Eradicate Ewing Sarcoma (Aune)

May 13, 2021

Despite the breakthroughs being made in treating many cancers with less toxic, targeted, and immune-based therapies, Ewing sarcoma’s 40-year-old chemotherapy regimen remains a significant contributor to mortality and long-term cardiovascular complicati …


BMC Bioinformatics: CancerSiamese: one-shot learning for predicting primary and metastatic tumor types unseen during model training (Chen Lab)

May 13, 2021

Milad Mostavi, Yu-Chiao Chiu, Yidong Chen & Yufei Huang Abstract Background The state-of-the-art deep learning-based cancer type prediction can only predict cancer types whose samples are available during the training where the sample size is commo …


Journal of Clinical Medicine: Recent Developments in Nanomedicine for Pediatric Cancer (Kurmasheva)

April 30, 2021

by  Shicheng Yang 1, Mia Wallach 2 , Apurva Krishna 3, Raushan Kurmasheva 4,5,*,†  and Srinivas Sridhar 1,3,6,*,† Abstract Cancer is the second biggest cause of death in children in the US. With the development of chemotherapy, there has been a substan …


International Journal of Molecular Sciences: A Comprehensive Analysis into the Therapeutic Application of Natural Products as SIRT6 Modulators in Alzheimer’s Disease, Aging, Cancer, Inflammation, and Diabetes (Rao Lab)

April 30, 2021

Raushanara Akter 1, Afrina Afrose 1, Md Rashidur Rahman 2, Rakhi Chowdhury 1, Saif Shahriar Rahman Nirzhor 3, Rubayat Islam Khan 4, Md Tanvir Kabir 1 ABSTRACT Natural products have long been used as drugs to treat a wide array of human diseases. The le …


JCM: Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children’s Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force (Houghton)

April 30, 2021

by  Holly L. Pacenta 1,2, Wendy Allen-Rhoades,  3, David Langenau,  4, Peter J. Houghton,  5, Charles Keller 6, Christine M. Heske,  7 , Michael D. Deel,  8, Corinne M. Linardic,  8 , Jack F. Shern 7, Elizabeth Stewart,  9, Brian Turpin,  10, Douglas J …


A review article by Dr. Raushan Kurmasheva (senior author) gives an overview on recent developments in nanomedicine for pediatric cancer

April 30, 2021

Recent Developments in Nanomedicine for Pediatric Cancer by Shicheng Yang 1, Mia Wallach 2OrcID, Apurva Krishna 3, Raushan Kurmasheva 4,5,*,†OrcID and Srinivas Sridhar 1,3,6,*,† Abstract Cancer is the second biggest cause of death in children in the US …


Frontiers in Molecular Biosciences: The Role of Human Centromeric RNA in Chromosome StabilityThe Role of Human Centromeric RNA in Chromosome Stability (Kitagawa Lab)

April 20, 2021

Introduction Accurate chromosome segregation is fundamental for cell division. Errors in this process can lead to chromosome instability, leading to aneuploidy, which is correlated with cancer (Zhu et al., 2011; Santaguida and Amon, 2015). The centrome …


The Journal of Clinical Medicine Special Issue: The Current Treatment of Childhood Cancer”, for which Dr. Raushan Kurmasheva is Guest Editor

April 20, 2021

Special Issue Information Dear Colleagues, In the last four decades, the 5-year survival rate of children with cancer has increased from 58% to 83%, with the standard of care for these children relying on surgery, radiation therapy, and systemic therap …


Cold Spring Harbor Molecular Case Studies: Bloom syndrome in a Mexican-American family with rhabdomyosarcoma: evidence of a Mexican founder mutation (Bishop, Chen, Tomlinson)

April 9, 2021

Erin H. Sybouts1,2,11, Adam D. Brown1,2,8,11, Maria G. Falcon-Cantrill3,9,11, Martha H. Thomas1,10, Thomas DeNapoli4,5, Julie Voeller5,6, Yidong Chen1,7, Gail E. Tomlinson1,3 and Alexander J.R. Bishop1,2 Abstract Bloom syndrome is a rare autosomal rece …