Greehey CCRI News & Events Archive
Nature Communications: MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma
October 31, 2018Nourhan Abdelfattah, Subapriya Rajamanickam, Subbarayalu Panneerdoss, Santosh Timilsina, Pooja Yadav, Benjamin C. Onyeagucha, Michael Garcia, Ratna Vadlamudi, Yidong Chen, Andrew Brenner, Peter Houghton & Manjeet K. Rao Abstract Despite improvement …
International Journal of Oncology: Novel polygodial analogs P3 and P27: Efficacious therapeutic agents disrupting mitochondrial function in oral squamous cell carcinoma
October 5, 2018Jorge De La Chapa, Prajjal Kanti Singha, Mckay Sallaway, Kristen Self, Ranna Nasreldin, Ramesh Dasari, Matthew Hart., Alexander Kornienko, Jeremy Just, Jason A. Smith, Alex C. Bissember, Cara B. Gonzales Abstract Polygodial, a drimane sesquiterpenoid …
Science Advances: Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression
October 3, 2018Subbarayalu Panneerdoss1,2,*, Vijay K. Eedunuri1,2,*, Pooja Yadav1,2, Santosh Timilsina1,2, Subapriya Rajamanickam2,3, Suryavathi Viswanadhapalli4, View ORCID ProfileNourhan Abdelfattah1,2, Benjamin C. Onyeagucha1,2, View ORCID ProfileXiadong Cui5, Zha …
American Journal of Surgery: Polytrauma independent of therapeutic intervention alters the gastrointestinal microbiome
October 1, 2018Susannah E Nicholson 1, Daniel Merrill 2, Caroline Zhu 3, David M Burmeister 4, Yi Zou 5, Zhao Lai 6, Daniel N Darlington 7, Aaron M Lewis 8, Larry Newton 9, Shannon Scroggins 10, Brian J Eastridge 11, Martin G Schwacha 12 Abstract Background: This stu …
Oncology: Immunogenic Heterogeneity of Renal Cell Carcinoma With Venous Tumor Thrombus
September 18, 2018Author links open overlay panelMichael A.Lissabcd YidongChenabcd RonaldRodriguezabcd DeepakPruthiabcd TeresaJohnson-PaisabcdHanzhangWangabcd AhmedMansourabcd DharamKaushikabcd Abstract Objective To perform immune-cell enumeration and programmed d …
FDA: The Voice of the Patient – Childhood Cancer Hearing Loss
September 13, 2018Introduction: On September 13, 2018, four advocacy organizations – Children’s Cause for Cancer Advocacy, Children’s Brain Tumor Foundation, Mattie Miracle Cancer Foundation, and Momcology – hosted an Externally-Led Patient-Focused Drug Development (EL- …
Elife: tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
September 7, 2018Myron S Ignatius # 1 2 3 4, Madeline N Hayes # 1 2 3, Finola E Moore 1 2 3, Qin Tang 1 2 3, Sara P Garcia 1, Patrick R Blackburn 5, Kunal Baxi 4, Long Wang 4, Alexander Jin 1, Ashwin Ramakrishnan 1, Sophia Reeder 1, Yidong Chen 4, Gunnlaugur Petur Niel …
eLife: tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
September 7, 2018Myron S Ignatius, Madeline N Hayes, Finola E Moore, Qin Tang, Sara P Garcia, Patrick R Blackburn, Kunal Baxi, Long Wang, Alexander Jin, Ashwin Ramakrishnan, Sophia Reeder, Yidong Chen, Gunnlaugur Petur Nielsen, Eleanor Y Chen, Robert P Hasserjian, Fran …
JCI Insight: IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
August 23, 2018Amy C. Gross,1 Hakan Cam,1,2 Doris A. Phelps,3 Amanda J. Saraf,2,4 Hemant K. Bid,1,2 Maren Cam,1 Cheryl A. London,5,6 Sarah A. Winget,1 Michael A. Arnold,7,8 Laura Brandolini,9 Xiaokui Mo,10 John M. Hinckley,1,11 Peter J. Houghton,3 and Ryan D. Roberts …
CRISPR – Journal: CRISPR-Based Editing Reveals Edge-Specific Effects in Biological Networks
August 1, 2018Yi Li, Chance M. Nowak, Daniel Withers, Alexander Pertsemlidis, Leonidas Bleris Abstract Unraveling the properties of biological networks is central to understanding both normal and disease cellular phenotypes. Networks consist of functional elements ( …