Greehey CCRI News & Events Archive

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Childhood Obesity: Characterization of the Stool Microbiome in Hispanic Preschool Children by Weight Status and Time

February 1, 2018

Emily B Hollister 1 2, Byron A Foster 3, Mahmoud Dahdouli 1 2, Jesica Ramirez 4, Zhao Lai 5 Abstract Background: Variations in gut microbiota composition and diversity have been associated with childhood adiposity, although most studies describing this …


Atlas of Science: The position of the centromere is marked with ubiquitylation of CENP-A

January 30, 2018

Chromosomes must segregate equally between daughter cells during cell division, and for proper chromosome segregation, spindle microtubules must attach to a single region of each chromosome, termed the “centromere,” in most eukaryotes. The kinetochore …


Journal of Biological Chemistry: Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates

January 19, 2018

Preston Countryman 1, Yanlin Fan 2, Aparna Gorthi 3 4, Hai Pan 1, Jack Strickland 1, Parminder Kaur 1, Xuechun Wang 5, Jiangguo Lin 1 6, Xiaoying Lei 2 7, Christian White 1, Changjiang You 8, Nicolas Wirth 9, Ingrid Tessmer 9, Jacob Piehler 8, Robert R …


Neuro-Oncology: Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma

January 1, 2018

Shaofang Wu, Shuzhen Wang, Feng Gao, Luyuan Li, Siyuan Zheng, W K Alfred Yung, Dimpy Koul Abstract Background Oncogenic activation of phosphatidylinositol-3 kinase (PI3K) signaling plays a pivotal role in the development of glioblastoma (GBM). However, …


ACS Journals: Addressing late effects and quality of life essential to improving survivorship care (Aune Lab)

December 14, 2017

Abstract This news section offers Cancer readers timely information on events, public policy analysis, topical issues, and personalities. In this issue, we highlight efforts being made to improve cancer survivorship care and mitigate the late effects o …


Genome Biology: The 3′ end of the story: deciphering combinatorial interactions that control mRNA fate.

November 29, 2017

Authors Penalva LOF Sanford JR Precise control of messenger RNA (mRNA) fate—its translation, stability, and localization—is required for accurate eukaryotic gene expression and is of fundamental importance to human health and disease. Initial efforts t …


Pediatric Blood & Cancer: Evaluation of patritumab with or without erlotinib in combination with standard cytotoxic agents against pediatric sarcoma xenograft models

October 28, 2017

Abhik Bandyopadhyay 1, Edward Favours 1, Doris A Phelps 1, Vanessa Del Pozo 1, Samson Ghilu 1, Dias Kurmashev 1, Joel Michalek 2, Aron Trevino 2, Denis Guttridge 3, Cheryl London 4, Kenji Hirotani 5, Ling Zhang 5, Raushan T Kurmasheva 1, Peter J Hought …


BMC Genomics: Genome-wide identification of key modulators of gene-gene interaction networks in breast cancer

October 3, 2017

Yu-Chiao Chiu, Li-Ju Wang, Tzu-Hung Hsiao, Eric Y. Chuang & Yidong Chen Abstract Background With the advances in high-throughput gene profiling technologies, a large volume of gene interaction maps has been constructed. A higher-level layer of gene …


BMC Bioinformatics: XBSeq2: a fast and accurate quantification of differential expression and differential polyadenylation

October 3, 2017

Yuanhang Liu, Ping Wu, Jingqi Zhou, Teresa L. Johnson-Pais, Zhao Lai, Wasim H. Chowdhury, Ronald Rodriguez & Yidong Chen Abstract Background RNA sequencing (RNA-seq) is a high throughput technology that profiles gene expression in a genome-wide man …


Science Signaling: Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies

September 26, 2017

Andrew M. Waters1,2, Irem Ozkan-Dagliyan3, Angelina V. Vaseva1,4, View ORCID ProfileNicole Fer2, Leslie A. Strathern2, View ORCID ProfileG. Aaron Hobbs1, View ORCID ProfileBasile Tessier-Cloutier5, View ORCID ProfileWilliam K. Gillette2, View ORCID Pro …


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