Greehey CCRI News & Events Archive
Non-Coding RNA, FibroDB: Expression Analysis of Protein-Coding and Long Non-Coding RNA Genes in Fibrosis (Bishop Lab)
February 25, 2022by Mirolyuba Ilieva 1ORCID,Henry E. Miller 2,3,4ORCID,Arav Agarwal 4,5,Gabriela K. Paulus 4,6,Jens Hedelund Madsen 1,Alexander J. R. Bishop 2,3,7ORCID,Sakari Kauppinen 1 and Shizuka Uchida 1,*ORCID Abstract Most long non-coding RNAs (lncRNAs) are expre …
Cancers: Global Genomic and Proteomic Analysis Identified Critical Pathways Modulated by Proto-Oncogene PELP1 in TNBC (Chen & Lai)
February 25, 2022by Zexuan Liu 1,2,†,Kristin A. Altwegg 1,3,†ORCID,Junhao Liu 1,2,Susan T. Weintraub 4,Yidong Chen 5,6,Zhao Lai 5,7,Gangadhara R. Sareddy 1,3,Suryavathi Viswanadhapalli 1,3,*ORCID and Ratna K. Vadlamudi 1,3,8,* Simple Summary The proto-oncogene PELP1 is …
Journal of Pediatric Hematology/Oncology: Extrarenal Anaplastic Wilms Tumor A Case Report With Genomic Analysis And Tumor Models (Kurmasheva & Houghton)
February 8, 2022Willis, Kelsi R. MS*; Sathe, Adwait A. PhD†; Xing, Chao PhD†,‡,§; Koduru, Prasad PhD*; Artunduaga, Maddy MD∥,¶; Butler, Erin B. MD#; Park, Jason Y. MD, PhD*,¶; Kurmasheva, Raushan T. PhD**,††; Houghton, Peter J. PhD**,††; Chen, Kenneth S. MD¶,#; Rakhej …
eLife: RNA ‘heroes’ can disarm bad-actor proteins in leukemia: study (Gupta)
February 3, 2022Brain, Behavior, & Immunity: Sex-dependent pain trajectories induced by prolactin require an inflammatory response for pain resolution (Lai Lab)
January 24, 2022Author links open overlay panelJenniferMecklenburga AndiWangzhouf Anahit H.Hovhannisyana PriscillaBarba-Escobedoa Sergey A.Sheinb YiZoud KorriWeldond ZhaoLaideVincentGoffing GregoryDussorf Alexei V.Tumanovb Theodore J.Pricef Armen N.Akopiana …
eLife: RNA binding to human METTL3-METTL14 restricts N6-deoxyadenosine methylation of DNA in vitro (Gupta Lab)
January 21, 2022Shan Qi, Javier Mota, Siu-Hong Chan, Johanna Villarreal, Nan Dai, Shailee Arya, Robert A Hromas, Manjeet K Rao, Ivan R Corrêa Jr Yogesh K Gupta Abstract Methyltransferase like-3 (METTL3) and METTL14 complex transfer a methyl group from S-aden …
Frontiers in Microbiology: Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor (Lai Lab)
January 20, 2022Yehong Huang1,2†, Wurihan Wurihan2†, Bin Lu1,2†, Yi Zou3, Yuxuan Wang2†, Korri Weldon3, Joseph D. Fondell2†, Zhao Lai3,4, Xiang Wu1*†, and Huizhou Fan2*† Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living bact …
Frontiers in Genetics: Differential lncRNA/mRNA Expression Profiling and Functional Network Analyses in Bmp2 Deletion of Mouse Dental Papilla Cells (Lai Lab)
January 20, 2022Feng Wang1,2†, Ran Tao1†, Li Zhao1, Xin-Hui Hao1, Yi Zou3, Qing Lin1, Meng Meng Liu2, Graham Goldman2, Daoshu Luo1* and Shuo Chen2* Bmp2 is essential for dentin development and formation. Bmp2 conditional knock-out (KO) mice display a similar tooth phe …
iScience: SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics (Aune)
January 19, 2022Karthik Ramachandran110 Soumya Maity110 Alagar R.Muthukumar2 Soundarya Kandala1 Dhanendra Tomar3 Tarek Mohamed Abd El-Aziz49 Cristel Allen1 Yuyang Sun5 Manigandan Venkatesan1 Travis R.Madaris1 Kevin Chiem6 RachelTruitt7 Neelanjan Vishnu1 G …
Urologic Oncology: Prevalence of pathogenic germline cancer risk variants in testicular cancer patients: Identifying high risk groups (Tomlinson)
January 19, 2022ChethanRamamurthyM.D.a‡Amin H.NassarM.D.bc‡SarahAbou AlaiwiM.D.bcElioAdibM.D.bcElie W.AklM.D.cShanYangPh.D.dEdward D.EsplinM.D., Ph.D.dMichael A.LissM.D.aGail E.TomlinsonM.D.eGuru P.SonpavdeM.D.b Highlights • Testicular cancer patients are at risk for …