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Pigment Cell & Melanoma: Segregation Between an Ornamental and a Disease Driver Gene Provides Insights Into Pigment Cell Regulation (Lai Lab)

September 25, 2024

Erika Soria, Qiusheng Lu, Will Boswell, Kang Du, Yanting Xing, Mikki Boswell, Korri S. Weldon, Zhao Lai, Markita Savage, Manfred Schartl, Yuan Lu ABSTRACT Genetic interactions are adaptive within a species. Hybridization can disrupt such species-specif …


Nature: Promotion of DNA end resection by BRCA1–BARD1 in homologous recombination (Sung, Libich)

September 12, 2024

Sameer Salunkhe, James M. Daley, Hardeep Kaur, Nozomi Tomimatsu, Chaoyou Xue, Vivek B. Raina, Angela M. Jasper, Cody M. Rogers, Wenjing Li, Shuo Zhou, Rahul Mojidra, Youngho Kwon, Qingming Fang, Jae-Hoon Ji, Aida Badamchi Shabestari, O’Taveon Fitzgeral …


Journal of the National Cancer Institute: Integrative multi-omics characterization of hepatocellular carcinoma in Hispanic patients (Zheng, Chen & Lai Labs)

September 4, 2024

Debodipta Das, PhD, Xiaojing Wang, PhD, Yu-Chiao Chiu, PhD, Hakim Bouamar, PhD, Francis E Sharkey, MD, Jorge E Lopera, MD, Zhao Lai, PhD, Susan T Weintraub, PhD, Xianlin Han, PhD, Yi Zou, MS, Hung-I H Chen, PhD, Carla R Zeballos Torrez, MD, PhD, Xiang …


JNCI Cancer Spectrum: Neighborhood-level social determinants of health burden among adolescent and young adult cancer patients and impact on overall survival (Aune)

September 3, 2024

Elizabeth R Rodriguez, BS, Tori Tonn, BS, Midhat Jafry, BS, Sairah Ahmed, MD, Branko Cuglievan, MD, J Andrew Livingston, MD, Christopher R Flowers, MD, Gregory J Aune, MD, PhD, Karen H Albritton, MD, Michael E Roth, MD, Qian Xiao, PhD, Michelle A T Hil …


Nature Communications: DSS1 restrains BRCA2’s engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis (Zhao)

August 20, 2024

Yuxin Huang, Wenjing Li, Tzeh Foo, Jae-Hoon Ji, Bo Wu, Nozomi Tomimatsu, Qingming Fang, Boya Gao, Melissa Long, Jingfei Xu, Rouf Maqbool, Bipasha Mukherjee, Tengyang Ni, Salvador Alejo, Yuan He, Sandeep Burma, Li Lan, Bing Xia & Weixing Zhao Abstra …


JNCI Cancer Spectrum: Neighborhood-level Social Determinants of Health Burden among AYA Cancer Patients and Impact on Overall Survival (Aune)

July 29, 2024

Elizabeth R Rodriguez, B.S, Tori Tonn, B.S, Midhat Jafry, B.S, Sairah Ahmed, M.D, Branko Cuglievan, M.D, J Andrew Livingston, M.D, Christopher R Flowers, M.D, Gregory J Aune, M.D., Ph.D, Karen H Albritton, M.D, Michael E Roth, M.D, Qian Xiao, Ph.D, Mic …


Science Advances: IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHCII complexes (Gupta Lab)

July 17, 2024

                  ZHIJUN QIU JIHANE KHALIFE,  PURUSHOTH ETHIRAJ CARINE JAAFAR,  AN-PING LIN,  KENNETH N. HOLDER,  JACOB P. RITTER,  LILLY CHIOU GABRIELA HUELGAS-MORALES SADIA ASLAM, ZHAO ZHANG ZHIJIE LIU SHA …


MDPI Cells: Comprehensive Review of Uterine Leiomyosarcoma: Pathogenesis, Diagnosis, Prognosis, and Targeted Therapy (Bishop Lab)

July 15, 2024

Qiwei Yang Obianuju Sandra Madueke-Laveaux Han Cun Marta Wlodarczyk Natalia Garcia Katia Candido Carvalho Ayman Al-Hendy Abstract Uterine leiomyosarcoma (uLMS) is the most common subtype of uterine sarcomas. They have a poor prognosis with high rates o …


JCO Precision Oncology: Disparate Rates of Germline Variants in Cancer Predisposition Genes in African American/Black Compared With Non-Hispanic White Individuals Between 2015 and 2022 (Tomlinson)

July 12, 2024

Rachel B. Wyatt Castillo, MS, CGC, Sarah M. Nielsen, MS, CGC, Elaine Chen, PhD, Brandie Heald, MS, CGC,, Rachel E. Ellsworth, PhD  Edward D. Esplin, MD, PhD, FACMG, and Gail E. Tomlinson, MD, PhD  Abstract Purpose African American/Black (AA/B) individu …


eLife: SERBP1 interacts with PARP1 and is Present in PARylation-Dependent Protein Complexes Regulating Splicing, Cell Division, and Ribosome Biogenesis (Penalva, Libich, et al)

July 3, 2024

Kira Breunig Xiufen Lei Mauro Montalbano Gabriela D. A. Guardia Shiva Ostadrahimi Victoria Alers Adam Kosti Jennifer Chiou Nicole Klein Corina Vinarov Lily Wang Mujia Li Weidan Song W. Lee Kraus David S. Libich Stefano Tiziani Susan T. Weintraub Pedro …