Greehey CCRI News & Events Archive

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Non-Coding RNA, FibroDB: Expression Analysis of Protein-Coding and Long Non-Coding RNA Genes in Fibrosis (Bishop Lab)

February 25, 2022

by Mirolyuba Ilieva 1ORCID,Henry E. Miller 2,3,4ORCID,Arav Agarwal 4,5,Gabriela K. Paulus 4,6,Jens Hedelund Madsen 1,Alexander J. R. Bishop 2,3,7ORCID,Sakari Kauppinen 1 and Shizuka Uchida 1,*ORCID Abstract Most long non-coding RNAs (lncRNAs) are expre …


Cancers: Global Genomic and Proteomic Analysis Identified Critical Pathways Modulated by Proto-Oncogene PELP1 in TNBC (Chen & Lai)

February 25, 2022

by Zexuan Liu 1,2,†,Kristin A. Altwegg 1,3,†ORCID,Junhao Liu 1,2,Susan T. Weintraub 4,Yidong Chen 5,6,Zhao Lai 5,7,Gangadhara R. Sareddy 1,3,Suryavathi Viswanadhapalli 1,3,*ORCID and Ratna K. Vadlamudi 1,3,8,* Simple Summary The proto-oncogene PELP1 is …


Journal of Pediatric Hematology/Oncology: Extrarenal Anaplastic Wilms Tumor A Case Report With Genomic Analysis And Tumor Models (Kurmasheva & Houghton)

February 8, 2022

Willis, Kelsi R. MS*; Sathe, Adwait A. PhD†; Xing, Chao PhD†,‡,§; Koduru, Prasad PhD*; Artunduaga, Maddy MD∥,¶; Butler, Erin B. MD#; Park, Jason Y. MD, PhD*,¶; Kurmasheva, Raushan T. PhD**,††; Houghton, Peter J. PhD**,††; Chen, Kenneth S. MD¶,#; Rakhej …


eLife: RNA ‘heroes’ can disarm bad-actor proteins in leukemia: study (Gupta)

February 3, 2022


Brain, Behavior, & Immunity: Sex-dependent pain trajectories induced by prolactin require an inflammatory response for pain resolution (Lai Lab)

January 24, 2022

Author links open overlay panelJenniferMecklenburga  AndiWangzhouf  Anahit H.Hovhannisyana  PriscillaBarba-Escobedoa  Sergey A.Sheinb  YiZoud  KorriWeldond  ZhaoLaideVincentGoffing  GregoryDussorf  Alexei V.Tumanovb  Theodore J.Pricef  Armen N.Akopiana …


eLife: RNA binding to human METTL3-METTL14 restricts N6-deoxyadenosine methylation of DNA in vitro (Gupta Lab)

January 21, 2022

Shan Qi,  Javier Mota,  Siu-Hong Chan,  Johanna Villarreal,  Nan Dai,  Shailee Arya,  Robert A Hromas,  Manjeet K Rao,  Ivan R Corrêa Jr  Yogesh K Gupta  Abstract Methyltransferase like-3 (METTL3) and METTL14 complex transfer a methyl group from S-aden …


Frontiers in Microbiology: Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor (Lai Lab)

January 20, 2022

Yehong Huang1,2†, Wurihan Wurihan2†, Bin Lu1,2†, Yi Zou3, Yuxuan Wang2†, Korri Weldon3, Joseph D. Fondell2†, Zhao Lai3,4, Xiang Wu1*†, and Huizhou Fan2*† Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living bact …


Frontiers in Genetics: Differential lncRNA/mRNA Expression Profiling and Functional Network Analyses in Bmp2 Deletion of Mouse Dental Papilla Cells (Lai Lab)

January 20, 2022

Feng Wang1,2†, Ran Tao1†, Li Zhao1, Xin-Hui Hao1, Yi Zou3, Qing Lin1, Meng Meng Liu2, Graham Goldman2, Daoshu Luo1* and Shuo Chen2* Bmp2 is essential for dentin development and formation. Bmp2 conditional knock-out (KO) mice display a similar tooth phe …


iScience: SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics (Aune)

January 19, 2022

Karthik Ramachandran110 Soumya Maity110  Alagar R.Muthukumar2  Soundarya Kandala1  Dhanendra Tomar3  Tarek Mohamed Abd El-Aziz49  Cristel Allen1  Yuyang Sun5  Manigandan Venkatesan1  Travis  R.Madaris1  Kevin Chiem6  RachelTruitt7  Neelanjan Vishnu1  G …


Urologic Oncology: Prevalence of pathogenic germline cancer risk variants in testicular cancer patients: Identifying high risk groups (Tomlinson)

January 19, 2022

ChethanRamamurthyM.D.a‡Amin H.NassarM.D.bc‡SarahAbou AlaiwiM.D.bcElioAdibM.D.bcElie W.AklM.D.cShanYangPh.D.dEdward D.EsplinM.D., Ph.D.dMichael A.LissM.D.aGail E.TomlinsonM.D.eGuru P.SonpavdeM.D.b Highlights • Testicular cancer patients are at risk for …