Greehey CCRI News & Events Archive

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PLOS One: Target specificity, “in vivo” pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing’s sarcoma, and rhabdomyosarcoma

July 27, 2017

Peter Y. Yu , Heather L. Gardner , Ryan Roberts, Hakan Cam, Seethalakshmi Hariharan, Ling Ren, Amy K. LeBlanc, Hui Xiao, Jiayuh Lin, Denis C. Guttridge, Xiaokui Mo, Chad E. Bennett, Christopher C. Coss, Yonghua Ling, Mitch A. Phelps, Peter Houghton, Ch …


Clinical Cancer Research: Bioluminescence Imaging Enhances Analysis of Drug Responses in a Patient-Derived Xenograft Model of Pediatric ALL

July 15, 2017

Luke Jones 1, Jennifer Richmond 1, Kathryn Evans 1, Hernan Carol 1, Duohui Jing 1, Raushan T Kurmasheva 2, Catherine A Billups 3, Peter J Houghton 2, Malcolm A Smith 4, Richard B Lock 5 Abstract Purpose: Robust preclinical models of pediatric acute lym …


Clinical Cancer Research: Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood

July 1, 2017

Maria Isabel Achatz, Christopher C. Porter, Laurence Brugières, Harriet Druker, Thierry Frebourg, William D. Foulkes, Christian P. Kratz, Roland P. Kuiper, Jordan R. Hansford, Hector Salvador Hernandez, Katherine L. Nathanson, Wendy K. Kohlmann, Leslie …


Clinical Cancer Research: Surveillance Recommendations for Children with Overgrowth Syndromes and Predisposition to Wilms Tumors and Hepatoblastoma

July 1, 2017

Jennifer M Kalish 1, Leslie Doros 2, Lee J Helman 3, Raoul C Hennekam 4, Roland P Kuiper 5, Saskia M Maas 6, Eamonn R Maher 7, Kim E Nichols 8, Sharon E Plon 9, Christopher C Porter 10, Surya Rednam 9, Kris Ann P Schultz 11, Lisa J States 12, Gail E To …


Clinical Cancer Research: Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood

July 1, 2017

Jonathan D Wasserman 1, Gail E Tomlinson 2, Harriet Druker 3, Junne Kamihara 4, Wendy K Kohlmann 5, Christian P Kratz 6, Katherine L Nathanson 7, Kristian W Pajtler 8 9, Andreu Parareda 10, Surya P Rednam 11, Lisa J States 12, Anita Villani 3, Michael …


Cell Report: The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma

June 13, 2017

Myron S Ignatius 1, Madeline N Hayes 2, Riadh Lobbardi 2, Eleanor Y Chen 3, Karin M McCarthy 4, Prethish Sreenivas 5, Zainab Motala 6, Adam D Durbin 7, Aleksey Molodtsov 4, Sophia Reeder 4, Alexander Jin 4, Sivasish Sindiri 8, Brian C Beleyea 9, Deepak …


Hepatology: A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH)

June 13, 2017

Jyoti Srivastava 1, Chadia L Robertson 1, Kareem Ebeid 2, Mikhail Dozmorov 3, Devaraja Rajasekaran 1, Rachel Mendoza 1, Ayesha Siddiq 1, Maaged A Akiel 1, Nidhi Jariwala 1, Xue-Ning Shen 1, Jolene J Windle 1, Mark A Subler 1, Nitai D Mukhopadhyay 3, Sh …


JAMA Oncology: Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525

June 1, 2017

Erica Hlavin Bell 1, Stephanie L Pugh 2, Joseph P McElroy 3, Mark R Gilbert 4, Minesh Mehta 5, Alexander C Klimowicz 6, Anthony Magliocco 7, Markus Bredel 8, Pierre Robe 9, Anca-L Grosu 10, Roger Stupp 11, Walter Curran Jr 12, Aline P Becker 1, Andrea …


Aging Cell: Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health

May 29, 2017

Ning Zhang 1, Joseph M Valentine 1, You Zhou 1, Mengyao E Li 1 2, Yiqiang Zhang 1, Arunabh Bhattacharya 1, Michael E Walsh 1, Katherine E Fischer 1, Steven N Austad 1, Pawel Osmulski 1, Maria Gaczynska 1, Steven E Shoelson 2, Holly Van Remmen 1, Hung I …


Nature: The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution

May 22, 2017

Hélène Badouin, Jérôme Gouzy, Christopher J. Grassa, Florent Murat, S. Evan Staton, Ludovic Cottret, Christine Lelandais-Brière, Gregory L. Owens, Sébastien Carrère, Baptiste Mayjonade, Ludovic Legrand, Navdeep Gill, Nolan C. Kane, John E. Bowers, Sari …


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