Greehey CCRI Archives
Greehey CCRI Faculty Awarded $1.2M CPRIT Grant to Support Osteosarcoma Research
Written by: Will Sansom An award of $1.2 million from the Cancer Prevention and Research Institute of Texas (CPRIT) went to Greehey CCRI Deputy Director and principal investigator Manjeet Rao, PhD, professor of cell systems and anatomy, for studies of …
Luiz O.F. Penalva, PhD, Co-corresponding Senior Author on NPJ Genomic Medicine publication.
“Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles” Abstract Therapy resistance and recurrence in high-grade gliomas are driven by their populations of glioma stem cells (GSCs). Thus, detailed molecul …
San Antonio Business Journals: San Antonio lands one of its largest cancer grant allocations ever to bring in more talent
February 20, 2020CPRIT officials said this is one of the largest collective awards the Alamo City has received in a single funding round.
Advances in Urology: Microbiome within Primary Tumor Tissue from Renal Cell Carcinoma May Be Associated with PD-L1 Expression of the Venous Tumor Thrombus
February 18, 2020Michael A. Liss,1 Yidong Chen,2 Ronald Rodriguez,1 Deepak Pruthi,1 Teresa Johnson-Pais,3 Hanzhang Wang,1 Ahmed Mansour,1 James R. White,4 and Dharam Kaushik1 Abstract Objective. To perform a proof of concept microbiome evaluation and PD-L1 expression p …
Cell Stem Cell: Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis
February 6, 2020Zhe Zhu, Pinar Mesci, Jean A Bernatchez, Ryan C Gimple, Xiuxing Wang, Simon T Schafer, Hiromi I Wettersten, Sungjun Beck, Alex E Clark, Qiulian Wu, Briana C Prager, Leo JY Kim, Rekha Dhanwani, Sonia Sharma, Alexandra Garancher, Sara M Weis, Stephen C M …
Springer: Prospective use of the single-mouse experimental design for the evaluation of PLX038A
January 11, 2020Samson Ghilu, Qilin Li, Shaun D. Fontaine, Daniel V. Santi, Raushan T. Kurmasheva, Siyuan Zheng & Peter J. Houghton Abstract Purpose Defining robust criteria for drug activity in preclinical studies allows for fewer animals per treatment group, and …
Endocrinology: Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer
January 2, 2020Sulgi Park, Chung-Seog Song, Chun-Lin Lin, Shoulei Jiang, Pawel A Osmulski, Chiou-Miin Wang, Brett T Marck, Alvin M Matsumoto, Colm Morrissey, Maria E Gaczynska, Yidong Chen, Elahe A Mostaghel, Bandana Chatterjee Abstract SULT2B1b (SULT2B) is a prostat …
Frontiers in Biosciences (Elite Ed) Cytogenetics of hepatoblastoma
January 2, 2020Gail E Tomlinson 1 Abstract The cytogenetics of hepatoblastoma demonstrate recurring events which include whole chromosome trisomies, most commonly trisomy of chromosome 2, 8, or 10. In addition, unbalanced translocations involving a breakpoint on the …
Molecular Cancer Research: ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state
January 1, 2020Adam Kosti, Liqin Du, Haridha Shivram, Mei Qiao, Suzanne Burns, Juan Gabriel Garcia, Alexander Pertsemlidis, Vishwanath R Iyer, Erzsebet Kokovay, Luiz OF Penalva 13-Cis-retinoic acid (RA) is typically used in postremission maintenance therapy in patien …
Scientific Reports: Genomic analyses of early responses to radiation in glioblastoma reveal new alterations at transcription, splicing, and translation levels
January 1, 2020Choudhary Saket, Suzanne C Burns, Mirsafian Hoda, Wenzheng Li, Dat T Vo, Qiao Mei, Lei Xiufen, Andrew D Smith, Luiz O Penalva High-dose radiation is the main component of glioblastoma therapy. Unfortunately, radio-resistance is a common problem and a m …