Greehey CCRI Archives

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Cancer Research: Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma

October 1, 2019

Xiaolong Li 1, Emmanuel Martinez-Ledesma 1 2, Chen Zhang 1, Feng Gao 1, Siyuan Zheng 1, Jie Ding 1, Shaofang Wu 1, Nghi Nguyen 3, Stephan C Clifford 3, Patrick Y Wen 4, Keith L Ligon 4, W K Alfred Yung 1, Dimpy Koul 5 Abstract PI3K-targeting therapy re …


Molecular Therapy – Oncolytics: The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5

September 27, 2019

Author links open overlay panelXiaojie Yu126, Yiqiang Zhang1, Binggen Wu13, Jonathan M.Kurie4, Alexander Pertsemlidis125 Chemoresistance and metastasis are the major reasons for non-small cell lung cancer (NSCLC) treatment failure and patient deaths. W …


KENS5: UT Health working to fight children’s cancer with Hyundai Hope on Wheels grant (Houghton, Aune, Ignatius mention)

September 24, 2019

UT Health working to fight children’s cancer with Hyundai Hope on Wheels grant To help in the fight against pediatric cancer, Hyundai Hope on Wheels presented two grants totaling $500,000 to UT Health San Antonio. SAN ANTONIO — UT Health San Antonio is …


BioSpace: Hyundai Hope On Wheels Presents UT Health San Antonio With Hyundai Young Investigator And Scholar Hope Grant Totaling A Combined $500,000 To Support Pediatric Cancer Research (Aune & Ignatius Labs)

September 23, 2019

Hyundai Hope On Wheels® (HHOW), a 501(c)(3) non-profit organization supported by Hyundai and its U.S. dealers, announces $500,000 Hyundai Young Investigator and Scholar Hope Grant to UT Health San Antonio to continue its long-standing fight against ped …


Yahoo Finance: Hyundai Hope On Wheels Presents UT Health San Antonio With Hyundai Young Investigator And Scholar Hope Grant Totaling A Combined $500,000 To Support Pediatric Cancer Research

September 23, 2019


Developmental Cell: CENP-A Ubiquitylation Is Indispensable to Cell Viability

September 23, 2019

Summary CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity, but how CENP-A is deposited at the centromere remains obscure. We previously reported that CENP-A K124 ubiquitylation, mediated by the CUL4A- …


September is Women in Medicine Month

September 19, 2019

  As part of the American Medical Association (AMA) “Women in Medicine Month”, we at the Greehey Children’s Cancer Research Institute – UT Health San Antonio would like to take a moment and celebrate the female faculty who have dedicated their car …


KENS5: UT Health gets a $306,000 grant to study Ewing sarcoma

September 16, 2019

SAN ANTONIO — September is Childhood Cancer Awareness Month. One of those cancers, Ewing sarcoma, is the second most common type of bone cancer in children with only 200 diagnosed each year in the U.S. Thanks to a $306,000 grant from The St. Baldrick’s …


PLOS Biology: Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption

September 12, 2019

Jun Liu , Ming Gao , Michael Nipper, Janice Deng, Francis E. Sharkey, Randy L. Johnson, Howard C. Crawford, Yidong Chen, Pei Wang  Abstract Damaged acinar cells play a passive role in activating pancreatic stellate cells (PSCs) via the recruitment of i …


UT Health San Antonio scientist continues study of children’s cancer using new grant to predict drug responses from genomic data (Chen Lab)

September 6, 2019