Greehey CCRI News & Events Archive

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Cell Press: A Modular Master Regulator Landscape Controls Cancer Transcriptional Identity (Zheng Lab)

January 21, 2021

Evan O.Paull114,  Alvaro Aytes121314,  Sunny J.Jones114,  Prem S.Subramaniam1,  Federico M.Giorgi3,  Eugene F.Douglass1,  Somnath Tagore1,  Brennan Chu1,  Alessandro Vasciaveo1,  Siyuan Zheng4,  Roel Verhaak5,  Cory Abate-Shen1678,  Mariano J.Alvarez19 …


Methods: Prediction and interpretation of cancer survival using graph convolution neural networks

January 21, 2021

RicardoRamireza, Yu-ChiaoChiub, SongYaoZhangc, JoshuaRamireza, YidongChenbd, YufeiHuangad, Yu-FangJina Highlights •  Predicting cancer survival outcomes using Graph Convolutional Neural Networks with TCGA dataset. •  Combining clinical data and the GCN …


MDPI: Synergism of Proneurogenic miRNAs Provides a More Effective Strategy to Target Glioma Stem Cells (Penalva & Pertsemlidis Labs)

January 14, 2021

Adam Kosti, Rodrigo Barreiro, Gabriela D. A. Guardia, Shiva Ostadrahimi, Erzsebet Kokovay, Alexander Pertsemlidis, Pedro A. F. Galante, Luiz O. F. Penalva Simple Summary miRNAs function as critical regulators of gene expression and have been defined as …


BMC Microbiology: Comparison of rectal swab, glove tip, and participant-collected stool techniques for gut microbiome sampling

January 14, 2021

Meghan I. Short, Robert Hudson, Benjamin D. Besasie, Kelly R. Reveles, Dimpy P. Shah, Susannah Nicholson, Teresa L. Johnson-Pais, Korri Weldon, Zhao Lai, Robin J. Leach, Bernard Fongang & Michael A. Liss Abstract Background Studies of the gut micro …


Nature Communications: Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma (Ignatius, Houghton, Chen)

January 14, 2021

Silvia Pomella, Prethish Sreenivas, Berkley E. Gryder, Long Wang, David Milewski, Matteo Cassandri, Kunal Baxi, Nicole R. Hensch, Elena Carcarino, Young Song, Hsien-Chao Chou, Marielle E. Yohe, Benjamin Z. Stanton, Bruno Amadio, Ignazio Caruana, Cristi …


Nature Communications: Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation (Zheng Lab)

January 12, 2021

        Nighat Noureen, Shaofang Wu, Yingli Lv, Juechen Yang, W. K. Alfred Yung, Jonathan Gelfond, Xiaojing Wang, Dimpy Koul, Andrew Ludlow & Siyuan Zheng Abstract Active telomerase is essential for stem cells and most cancers t …


Cancer Letters: COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice

January 9, 2021

Author links open overlay panelRosângela MayerGonçalvesa,  MarinaDelgoboa, Jonathan PauloAgnesa, Raquel Nascimentodas Nevesa, MarceloFalchettia, TuanyCasagrandea, Ana Paula VargasGarciab, Thaynan CunhaVieirab, NauanaSomensic, Maciel AlencarBruxeld, Dan …


Emily Selig of Libich Lab, Awarded a Spot on CPRIT Training Grant

January 8, 2021

      Emily Selig recently earned her PhD at the University of Melbourne, Australia where she was employing biophysical and biochemical approaches to investigate the mechanisms by which the small heat-shock proteins aB-crystallin and hea …


MDPI: MSI1 Promotes the Expression of the GBM Stem Cell Marker CD44 by Impairing miRNA-Dependent Degradation

December 5, 2020

Rebecca Pötschke  1,2,†, Jacob Haase  1,†, Markus Glaß  1, Sebastian Simmermacher  3, Claudia Misiak  1, Luiz O. F. Penalva  4,5, Caspar D. Kühnöl  2,* and Stefan Hüttelmaier  1,* Simple Summary Glioblastoma (GBM) is the most lethal brain tumor with a …


Molecular Oncology: Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling

December 2, 2020

Junhao Liu, Zexuan Liu, Mengxing Li, , Weiwei Tang, Uday P. Pratap, Yiliao Luo, Kristin A. Altwegg, Xiaonan Li, Yi Zou, Hong Zhu, Gangadhara R. Sareddy,  Suryavathi Viswanadhapalli, Ratna K. Vadlamudi Abstract A significant proportion of estrogen recep …