Greehey CCRI News & Events Archive

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Advances in Bioinformatics: Computational and Statistical Approaches for Modeling of Proteomic and Genomic Networks

March 13, 2013

Mario Flores,1 Tzu-Hung Hsiao,2 Yu-Chiao Chiu,3 Eric Y. Chuang,3 Yufei Huang,1 and Yidong Chen2,4 Abstract Common microarray and next-generation sequencing data analysis concentrate on tumor subtype classification, marker detection, and transcriptional …


Cell: Jmjd3 Inhibits Reprogramming by Upregulating Expression of INK4a/Arf and Targeting PHF20 for Ubiquitination

February 28, 2013

WeiZhao1 QingtianLi1, StephenAyers2, YifengGu1, ZhongShi3, QingyuanZhu1, YidongChen4, Helen Y.Wang1, Rong-FuWang1 Summary Although somatic cell reprogramming to generate inducible pluripotent stem cells (iPSCs) is associated with profound epigenetic ch …


Translational Cancer Research: Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma

February 1, 2013

Tzu-Hung Hsiao, Hung-I Harry Chen, Jo-Yang Lu, Pei-Ying Lin, Charles Keller, Sarah Comerford, Gail E. Tomlinson, Yidong Chen Abstract Extracting maximal information from gene signature sets (GSSs) via microarray-based transcriptional profiling involves …


PLOS One: Genomic Loss of Tumor Suppressor miRNA-204 Promotes Cancer Cell Migration and Invasion by Activating AKT/mTOR/Rac1 Signaling and Actin Reorganization

December 21, 2012

J. Saadi Imam, Jason R. Plyler , Hima Bansal , Suresh Prajapati , Sanjay Bansal, Jennifer Rebeles, Hung-I Harry Chen, Yao-Fu Chang, Subbarayalu Panneerdoss, Behyar Zoghi, Kalyan C. Buddavarapu, Russell Broaddus, Peter Hornsby, Gail Tomlinson, Jeffrey D …


Pediatric Blood & Cancer: Children’s Oncology Group’s 2013 blueprint for research: rare tumors

December 19, 2012

Carlos Rodriguez-Galindo 1, Mark Krailo, Lindsay Frazier, Murali Chintagumpala, James Amatruda, Howard Katzenstein, Marcio Malogolowkin, Logan Spector, Farzana Pashankar, Rebecka Meyers, Gail Tomlinson, COG Rare Tumors Disease Committee Abstract In the …


BMC Genomics: A Bayesian decision fusion approach for microRNA target prediction

December 17, 2012

Dong Yue, Maozu Guo, Yidong Chen & Yufei Huang Abstract MicroRNAs (miRNAs) are 19-25 nucleotides non-coding RNAs known to have important post-transcriptional regulatory functions. The computational target prediction algorithm is vital to effective …


BMC Genomics: Reducing confounding and suppression effects in TCGA data: an integrated analysis of chemotherapy response in ovarian cancer

October 26, 2012

Fang-Han Hsu, Erchin Serpedin, Tzu-Hung Hsiao, Alexander JR Bishop, Edward R Dougherty & Yidong Chen Abstract Background Despite initial response in adjuvant chemotherapy, ovarian cancer patients treated with the combination of paclitaxel and carbo …


BMC Genomics: Pathway Distiller – multisource biological pathway consolidation

October 26, 2012

Mark S Doderer, Zachry Anguiano, Uthra Suresh, Ravi Dashnamoorthy, Alexander JR Bishop & Yidong Chen  Abstract Background One method to understand and evaluate an experiment that produces a large set of genes, such as a gene expression microarray a …


BMC Genomics: Selected articles from the IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS’2011)

October 13, 2012

Ranadip Pal, Yufei Huang & Yidong Chen Introduction The 2011 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS 2011) was organized in San Antonio, Texas from December 2-4th. GENSIPS’11 provided a forum for researchers …


Annals of Diagnostic Pathology: Isolated vaginal myeloid sarcoma in a 16-year-old girl

October 1, 2012

Maria Luisa C, Policarpio-NicolasMDa, Philip T.ValenteMDa , Gregory J.Aune MD, PhDb , Russell A.HigginsMDa Abstract Involvement of the female genital tract by myeloid sarcoma as the initial presentation is extremely uncommon, especially in the vagina. …


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