Greehey CCRI News & Events Archive
Cancer Epidemiology Biomarkers & Prevevention: Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers
August 1, 2011Susan L Neuhausen 1, Sean Brummel, Yuan Chun Ding, Linda Steele, Katherine L Nathanson, Susan Domchek, Timothy R Rebbeck, Christian F Singer, Georg Pfeiler, Henry T Lynch, Judy E Garber, Fergus Couch, Jeffrey N Weitzel, Andrew Godwin, Steven A Narod, P …
Cancer Research: Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes
July 28, 2011Timothy R Rebbeck 1, Nandita Mitra, Susan M Domchek, Fei Wan, Tara M Friebel, Teo V Tran, Christian F Singer, Muy-Kheng Maria Tea, Joanne L Blum, Nadine Tung, Olufunmilayo I Olopade, Jeffrey N Weitzel, Henry T Lynch, Carrie L Snyder, Judy E Garber, Ant …
JAMA Network: Clinically relevant changes in family history of cancer over time
July 13, 2011Argyrios Ziogas 1, Nora K Horick, Anita Y Kinney, Jan T Lowery, Susan M Domchek, Claudine Isaacs, Constance A Griffin, Patricia G Moorman, Karen L Edwards, Deirdre A Hill, Jonathan S Berg, Gail E Tomlinson, Hoda Anton-Culver, Louise C Strong, Carol H K …
Cancer Epidemiology Biomarkers & Prevention: Polymorphisms in CYP1A1 and ethnic-specific susceptibility to acute lymphoblastic leukemia in children.
July 1, 2011Ryan M Swinney 1, Joke Beuten, Anderson B Collier 3rd, Tina T-L Chen, Naomi J Winick, Brad H Pollock, Gail E Tomlinson Abstract Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. The U.S. Surveillance Epidemiology a …
Pediatric Developmental Pathology: Activated NOTCH2 is overexpressed in hepatoblastomas: an immunohistochemical study
June 3, 2011Jason B Litten 1, Tina T-L Chen, Roger Schultz, Karl Herman, Jessica Comstock, Joshua Schiffman, Gail E Tomlinson, Dinesh Rakheja Abstract Hepatoblastoma is a pediatric malignancy characterized by the uncontrolled proliferation of immature hepatocytes …
Cancer Epidemiology Biomarkers & Prevention: Multilocus association of genetic variants in MLL, CREBBP, EP300, and TOP2A with childhood acute lymphoblastic leukemia in Hispanics from Texas
June 1, 2011Duangjai Piwkham 1, Jonathan A L Gelfond, Budsaba Rerkamnuaychoke, Samart Pakakasama, Vivienne I Rebel, Brad H Pollock, Naomi J Winick, Anderson B Collier 3rd, Gail E Tomlinson, Joke Beuten Abstract Background: Hispanic children have both a higher inci …
Plos One: Preferential Localization of Human Origins of DNA Replication at the 5′-Ends of Expressed Genes and at Evolutionarily Conserved DNA Sequences
May 13, 2011Manuel S. Valenzuela ,Yidong Chen ,Sean Davis,Fan Yang,Robert L. Walker,Sven Bilke,John Lueders,Melvenia M. Martin,Mirit I. Aladjem,Pierre P. Massion, Paul S. Meltzer Abstract Background Replication of mammalian genomes requires the activation of tho …
JoVE Journal: Dissection of a Mouse Eye for a Whole Mount of the Retinal Pigment Epithelium
February 27, 2011Alison Claybon1, Alexander J. R. Bishop1 Abstract The retinal pigment epithelium (RPE) lies at the back of the mammalian eye, just under the neural retina, which contains the photoreceptors (rods and cones). The RPE is a monolayer of pigmented cuboidal …
Cancer Cell: Evidence for an Unanticipated Relationship between Undifferentiated Pleomorphic Sarcoma and Embryonal Rhabdomyosarcoma
February 1, 2011Brian P.Rubin1, KoichiNishijo2, Hung-I HarryChen2, XiaolanYi2, David P.Schuetze1, RanadipPal3, Suresh I.Prajapati2, JinuAbraham2, Benjamin R.Arenkiel4, Qing-RongChen5, SeanDavis6, Amanda T.McCleish2, Mario R.Capecchi7, Joel E.Michalek8, Lee AnnZarzabal …
Journal of Molecular Cancer Biology: Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation
January 28, 2011Liqin Du, Alexander Pertsemlidis Abstract Although cancer and neurodegenerative disease are two distinct pathological disorders, emerging evidence indicates that these two types of disease share common mechanisms of genetic and molecular abnormalities. …