Greehey CCRI News & Events Archive

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Cancer Epidemiology Biomarkers & Prevevention: Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers

August 1, 2011

Susan L Neuhausen 1, Sean Brummel, Yuan Chun Ding, Linda Steele, Katherine L Nathanson, Susan Domchek, Timothy R Rebbeck, Christian F Singer, Georg Pfeiler, Henry T Lynch, Judy E Garber, Fergus Couch, Jeffrey N Weitzel, Andrew Godwin, Steven A Narod, P …


Cancer Research: Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes

July 28, 2011

Timothy R Rebbeck 1, Nandita Mitra, Susan M Domchek, Fei Wan, Tara M Friebel, Teo V Tran, Christian F Singer, Muy-Kheng Maria Tea, Joanne L Blum, Nadine Tung, Olufunmilayo I Olopade, Jeffrey N Weitzel, Henry T Lynch, Carrie L Snyder, Judy E Garber, Ant …


JAMA Network: Clinically relevant changes in family history of cancer over time

July 13, 2011

Argyrios Ziogas 1, Nora K Horick, Anita Y Kinney, Jan T Lowery, Susan M Domchek, Claudine Isaacs, Constance A Griffin, Patricia G Moorman, Karen L Edwards, Deirdre A Hill, Jonathan S Berg, Gail E Tomlinson, Hoda Anton-Culver, Louise C Strong, Carol H K …


Cancer Epidemiology Biomarkers & Prevention: Polymorphisms in CYP1A1 and ethnic-specific susceptibility to acute lymphoblastic leukemia in children.

July 1, 2011

Ryan M Swinney 1, Joke Beuten, Anderson B Collier 3rd, Tina T-L Chen, Naomi J Winick, Brad H Pollock, Gail E Tomlinson Abstract Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. The U.S. Surveillance Epidemiology a …


Pediatric Developmental Pathology: Activated NOTCH2 is overexpressed in hepatoblastomas: an immunohistochemical study

June 3, 2011

Jason B Litten 1, Tina T-L Chen, Roger Schultz, Karl Herman, Jessica Comstock, Joshua Schiffman, Gail E Tomlinson, Dinesh Rakheja Abstract Hepatoblastoma is a pediatric malignancy characterized by the uncontrolled proliferation of immature hepatocytes …


Cancer Epidemiology Biomarkers & Prevention: Multilocus association of genetic variants in MLL, CREBBP, EP300, and TOP2A with childhood acute lymphoblastic leukemia in Hispanics from Texas

June 1, 2011

Duangjai Piwkham 1, Jonathan A L Gelfond, Budsaba Rerkamnuaychoke, Samart Pakakasama, Vivienne I Rebel, Brad H Pollock, Naomi J Winick, Anderson B Collier 3rd, Gail E Tomlinson, Joke Beuten Abstract Background: Hispanic children have both a higher inci …


Plos One: Preferential Localization of Human Origins of DNA Replication at the 5′-Ends of Expressed Genes and at Evolutionarily Conserved DNA Sequences

May 13, 2011

Manuel S. Valenzuela  ,Yidong Chen ,Sean Davis,Fan Yang,Robert L. Walker,Sven Bilke,John Lueders,Melvenia M. Martin,Mirit I. Aladjem,Pierre P. Massion, Paul S. Meltzer  Abstract Background Replication of mammalian genomes requires the activation of tho …


JoVE Journal: Dissection of a Mouse Eye for a Whole Mount of the Retinal Pigment Epithelium

February 27, 2011

Alison Claybon1, Alexander J. R. Bishop1 Abstract The retinal pigment epithelium (RPE) lies at the back of the mammalian eye, just under the neural retina, which contains the photoreceptors (rods and cones). The RPE is a monolayer of pigmented cuboidal …


Cancer Cell: Evidence for an Unanticipated Relationship between Undifferentiated Pleomorphic Sarcoma and Embryonal Rhabdomyosarcoma

February 1, 2011

Brian P.Rubin1, KoichiNishijo2, Hung-I HarryChen2, XiaolanYi2, David P.Schuetze1, RanadipPal3, Suresh I.Prajapati2, JinuAbraham2, Benjamin R.Arenkiel4, Qing-RongChen5, SeanDavis6, Amanda T.McCleish2, Mario R.Capecchi7, Joel E.Michalek8, Lee AnnZarzabal …


Journal of Molecular Cancer Biology: Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation

January 28, 2011

Liqin Du, Alexander Pertsemlidis Abstract Although cancer and neurodegenerative disease are two distinct pathological disorders, emerging evidence indicates that these two types of disease share common mechanisms of genetic and molecular abnormalities. …


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