Greehey CCRI News & Events Archive

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PLOS One: 14-3-3 σ Expression Effects G2/M Response to Oxygen and Correlates with Ovarian Cancer Metastasis

January 10, 2011

Dashnamoorthy Ravi, Yidong Chen, Bijal Karia, Adam Brown, Ting Ting Gu, Jie Li, Mark S. Carey, Bryan T. Hennessy, Abstract Background In vitro cell, culture experiments with primary cells have reported that cell proliferation is retarded in the presenc …


Biological Psychology: The serotonin transporter gene and startle response during nicotine deprivation

January 1, 2011

Jennifer A Minnix 1, Jason D Robinson, Cho Y Lam, Brian L Carter, Jennifer E Foreman, David J Vandenbergh, Gail E Tomlinson, David W Wetter, Paul M Cinciripini Abstract Affective startle probe methodology was used to examine the effects of nicotine adm …


Cancer Genetics: Identification of genetic susceptibility to childhood cancer through analysis of genes in parallel

January 1, 2011

Sharon E Plon 1, David A Wheeler, Louise C Strong, Gail E Tomlinson, Michael Pirics, Qingchang Meng, Hannah C Cheung, Phyllis R Begin, Donna M Muzny, Lora Lewis, Jaclyn A Biegel, Richard A Gibbs Erratum in Cancer Genet. 2011 May;204(5):284 Abstract Cli …


Cancer Research: Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

December 1, 2010

Antonis C Antoniou 1, Jonathan Beesley, Lesley McGuffog, Olga M Sinilnikova, Sue Healey, Susan L Neuhausen, Yuan Chun Ding, Timothy R Rebbeck, Jeffrey N Weitzel, Henry T Lynch, Claudine Isaacs, Patricia A Ganz, Gail Tomlinson, Olufunmilayo I Olopade, F …


BMC Genomics: Robust inference of the context specific structure and temporal dynamics of gene regulatory network

December 1, 2010

Jia Meng, Mingzhu Lu, Yidong Chen, Shou-Jiang Gao & Yufei Huang Abstract Background The response of cells to changing endogenous or exogenous conditions is governed by intricate molecular interactions or regulatory networks. To lead to appropriate …


BMC Genomics: A Bayesian approach for identifying miRNA targets by combining sequence prediction and gene expression profiling

December 1, 2010

Hui Liu, Dong Yue, Lin Zhang, Yidong Chen, Shou-Jiang Gao & Yufei Huang Abstract Background MicroRNAs (miRNAs) are single-stranded non-coding RNAs shown to plays important regulatory roles in a wide range of biological processes and diseases. The f …


Breast Cancer Research & Treatment: Germline mutations in PALB2 in African-American breast cancer cases

November 27, 2010

Yuan Chun Ding 1, Linda Steele, Li-Hao Chu, Karen Kelley, Helen Davis, Esther M John, Gail E Tomlinson, Susan L Neuhausen Abstract Breast cancer incidence is lower in African Americans than in Caucasian Americans. However, African-American women have h …


Blood: Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias

November 25, 2010

Hima Bansal 1, Sanjay Bansal, Manjeet Rao, Kevin P Foley, Jim Sang, David A Proia, Ronald K Blackman, Weiwen Ying, James Barsoum, Maria R Baer, Kevin Kelly, Ronan Swords, Gail E Tomlinson, Minoo Battiwalla, Francis J Giles, Kelvin P Lee, Swaminathan Pa …


BMC Bioinformatics: Improving performance of mammalian microRNA target prediction

September 22, 2010

Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao & Yufei Huang Abstract Background MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA …


Journal of Nucleic Acids: Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA Deletion

August 19, 2010

Adam D. Brown,1,2 Alison B. Claybon,1 and Alexander J. R. Bishop1,2 Abstract Werner syndrome is a rare disorder that manifests as premature aging and age-related diseases. WRN is the gene mutated in WS, and is one of five human RecQ helicase family mem …


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