Greehey CCRI News & Events Archive
New England Journal of Medicine: MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer
October 8, 2009Junfang Ji, PhD, Jiong Shi, MD, Anuradha Budhu, PhD, Zhipeng Yu, B.S., Marshonna Forgues, B.S., Stephanie Roessler, PhD, Stefan Ambs, PhD, M.P.H., Yidong Chen, PhD, Paul S. Meltzer, MD, Carlo M. Croce, MD, Lun-Xiu Qin, MD, PhD, Kwan Man, MD, PhD, Abstr …
Cancer Research: Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers
July 1, 2009Timothy R Rebbeck 1, Nandita Mitra, Susan M Domchek, Fei Wan, Shannon Chuai, Tara M Friebel, Saarene Panossian, Amanda Spurdle, Georgia Chenevix-Trench, kConFab; Christian F Singer, Georg Pfeiler, Susan L Neuhausen, Henry T Lynch, Judy E Garber, Jeffre …
Pediatric Blood & Cancer: Small cell undifferentiated variant of hepatoblastoma: adverse clinical and molecular features similar to rhabdoid tumors
March 1, 2009Angela D Trobaugh-Lotrario 1, Gail E Tomlinson, Milton J Finegold, Lia Gore, James H Feusner Abstract Background: Small cell undifferentiated (SCU) histology in patients with stage I hepatoblastoma (HB) predicts an increased risk of relapse. We sought …
UT Health SA Newsroom: Noted childhood cancer researchers to meet in San Antonio
February 9, 2009About 100 scientists from noted cancer centers will gather in downtown San Antonio Feb. 26-27 to share findings and exchange ideas at the Genetics and Biology of Childhood Cancer 2009 symposium. It is the first scientific meeting sponsored by The Greeh …
Cancer Research: Large-Scale Profiling of Archival Lymph Nodes Reveals Pervasive Remodeling of the Follicular Lymphoma Methylome
February 1, 2009J. Keith Killian, Sven Bilke, Sean Davis, Robert L. Walker, M. Scott Killian, Erich B. Jaeger, Yidong Chen, Jason Hipp, Stefania Pittaluga, Mark Raffeld, Robert Cornelison, William I. Smith, Jr., Marina Bibikova, Jian-Bing Fan, Michael R. Emmert-Buck, …
Bioinformatics: GEOmetadb: powerful alternative search engine for the Gene Expression Omnibus
December 1, 2008Yuelin Zhu, Sean Davis, Robert Stephens, Paul S. Meltzer, Yidong Chen Abstract The NCBI Gene Expression Omnibus (GEO) represents the largest public repository of microarray data. However, finding data in GEO can be challenging. We have developed GEOmet …
Cancer Research: Common familial colorectal cancer linked to chromosome 7q31: a genome-wide analysis
November 1, 2008Deborah W Neklason 1, Richard A Kerber, David B Nilson, Hoda Anton-Culver, Ann G Schwartz, Constance A Griffin, Jan T Lowery, Joellen M Schildkraut, James P Evans, Gail E Tomlinson, Louise C Strong, Alexander R Miller, Jill E Stopfer, Dianne M Finkelst …
Bioinformatics: A probe-density-based analysis method for array CGH data: simulation, normalization and centralization
October 1, 2008Hung-I Harry Chen, Fang-Han Hsu, Yuan Jiang, Mong-Hsun Tsai, Pan-Chyr Yang, Paul S. Meltzer, Eric Y. Chuang, Yidong Chen Abstract Motivation: Genomic instability is one of the fundamental factors in tumorigenesis and tumor progression. Many studies hav …
Journal of Biomolecular Screening: An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme
September 13, 2008Amy M Wiles 1, Dashnamoorthy Ravi, Selvaraj Bhavani, Alexander J R Bishop Abstract Genome-wide RNA interference (RNAi) screening allows investigation of the role of individual genes in a process of choice. Most RNAi screens identify a large number of g …
Harvard Medical School, DRSC/TRiP Functional Genomics Resources: An Analysis of Normalization Methods for Drosophila RNAi Genomic Screens and Development of a Robust Validation Scheme
September 1, 2008AMY M. WILES,* DASHNAMOORTHY RAVI,* SELVARAJ BHAVANI, and ALEXANDER J. R. BISHOP Genome-wide RNA interference (RNAi) screening allows investigation of the role of individual genes in a process of choice. Most RNAi screens identify a large number of gen …