Greehey CCRI Archives

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NAR Cancer: The 3D Chromatin Landscape of Rhabdomyosarcoma (Ignatius Lab)

June 16, 2023

  Meng Wang, Prethish Sreenivas, Benjamin D Sunkel, Long Wang, Myron Ignatius, Benjamin Z Stanton Abstract Rhabdomyosarcoma (RMS) is a pediatric soft tissue cancer with a lack of precision therapy options for patients. We hypothesized that with a gener …

Paulomi Modi (Ignatius Lab) Recognized as 2023 Presidential Ambassador Scholar

May 8, 2023

Ambassadors from left to right: Gina Baxter (SHP), Avani Ved (SON), Paulomi Modi (GSBS), Alejandra Garcia (LSOM) and Tyler Childs (SOD) Paulomi Modi is a second-year PhD student in the Integrated Biomedical Sciences program at the Graduate School of Bi …

Molecular Cancer Theraputics: Sensitization to Ionizing Radiation by MEK Inhibition Is Dependent on SNAI2 in Fusion-Negative Rhabdomyosarcoma (Ignatius, Vaseva, Houghton Labs)

January 3, 2023

Nicole R. Hensch, Kathryn Bondra, Long Wang, Prethish Sreenivas, Xiang R. Zhao, Paulomi Modi, Angelina V. Vaseva, Peter J. Houghton, Myron S. Ignatius Abstract In fusion-negative rhabdomyosarcoma (FN-RMS), a pediatric malignancy with skeletal muscle ch …

Nicole Hensch (Ignatius Lab) Successfully Defends PhD Thesis!

May 17, 2022

“SNAI2 protection of rhabdomyosarcoma against ionizing radiation can be targeted through MEK inhibition in RAS-mutant fusion-negative tumors”               Nicole Hensch Mentor: Myron Ignatius, PhD Program: PhD Integr …

JCO Oncology Practice: Disparities in Cancer Genetic Testing and Variants of Uncertain Significance in the Hispanic Population of South Texas (Tomlinson Lab, Ignatius Lab)

May 12, 2022

Stephanie Soewito, BS, MS1; Rachel Wyatt, MS2; Emily Berenson, MS2; Natalie Poullard, MS, MA3; Shawn Gessay, MS2,3,4; Lindsey Mette, MS, MPH2,3,5; Elena Marin, CHW6; Kristin Shelby, BA6; Elise Alvarez, BA3; Byeong Yeob Choi, PhD7; Clarissa Aviles, MSHS …

SAVE-THE-DATE: San Antonio Pediatric Cancer Symposium (SAPCS)

May 10, 2022

The San Antonio Pediatric Cancer Symposium (SAPCS), hosted by the Greehey Children’s Cancer Research Institute at UT Health San Antonio and in conjunction with the Mays Cancer Center, will bring together some of the most respected childhood cancer rese …

Cellular Oncology: Single-cell RNA profiling identifies diverse cellular responses to EWSR1/FLI1 down regulation in Ewing sarcoma cells (Houghton, Chen, Kitagawa, Ignatius)

January 12, 2022

Roxane Khoogar, Fuyang Li, Yidong Chen, Myron Ignatius, Elizabeth R. Lawlor, Katsumi Kitagawa, Tim H.-M. Huang, Doris A. Phelps & Peter J. Houghton Background The EWSR1/FLI1 gene fusion is the most common rearrangement leading to cell transformatio …

CANCER RESEARCH: SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation (Houghton, Ignatius, Vaseva, and Zheng labs)

November 24, 2021

Long Wang, Nicole R. Hensch, Kathryn Bondra, Prethish Sreenivas, Xiang R. Zhao, Jiangfei Chen, Rodrigo Moreno Campos, Kunal Baxi, Angelina V. Vaseva, Benjamin D. Sunkel, Berkley E. Gryder, Silvia Pomella, Benjamin Z. Stanton, Siyuan Zheng, Eleanor Y. C …

Molecular Cancer Therapeutics: Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis and Tumor Regression in H/NRAS Q61X-mutant Rhabdomyosarcoma (Houghton, Chen, Ignatius, Vaseva)

November 8, 2021

Natalia Garcia, Vanessa Del Pozo, Marielle E. Yohe, Craig M. Goodwin, Terry J Shackleford, Long Wang, Kunal Baxi, Yidong Chen, Anna T Rogojina, Sara M. Zimmerman, Cody J. Peer, William D. Figg, Myron S. Ignatius, Kris C Wood, Peter J. Houghton, and Ang …

Journal of Palliative Medicine: When a Tumor Becomes a Legacy: A Collection of Perspectives (Ignatius & Tomlinson Labs)

October 4, 2021

Amanda E. Lipsitt, Patricia K. DeForest, Andrea J. Canon, Andrea R. Gilbert, and Gail E. Tomlinson Introduction The following is a story in the form of a collection of personal perspectives from our medical team members who treated a young woman with o …

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