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SAVE-THE-DATE: San Antonio Pediatric Cancer Symposium (SAPCS)

May 10, 2022

The San Antonio Pediatric Cancer Symposium (SAPCS), hosted by the Greehey Children’s Cancer Research Institute at UT Health San Antonio and in conjunction with the Mays Cancer Center, will bring together some of the most respected childhood cancer rese …

Pertsemlidis Lab Awarded American Lung Association Grant to Study “Identifying Exploitable Biomarkers of Lung Cancer Metastasis”

June 16, 2021

Greehey CCRI Principal Investigator, Alexander Pertsemlidis, PhD Abstract Rationale. Most cancer deaths are caused by metastatic disease, and the prevention of metastasis is a significant focus of clinical research. Aberrant expression of miRNAs has be …

Shaimar R. González Morales, MS (Pertsemlidis Lab) 2021 Dissertation Ford Foundation Fellowship Award

May 26, 2021

                Congratulations to Shaimar R. González Morales, MS, a graduate student in the lab of Alexander Pertsemlidis, PhD was just awarded a 2021 Dissertation Ford Foundation Fellowship Award, administered …

FASEB Journal: Identification of a novel mechanism for meso‐tetra (4‐carboxyphenyl) porphyrin (TCPP) uptake in cancer cells

February 25, 2021

            David J. Elzi,   William E. Bauta,  Jamila R. Sanchez,  Trisha Das, Shweta Mogare, Peter Zannes Fatland,  Moises Iza, Alexander Pertsemlidis,  Vivienne I. Rebel  Abstract Porphyrins are used for cancer diagnost …

MDPI: Synergism of Proneurogenic miRNAs Provides a More Effective Strategy to Target Glioma Stem Cells (Penalva & Pertsemlidis Labs)

January 14, 2021

Adam Kosti, Rodrigo Barreiro, Gabriela D. A. Guardia, Shiva Ostadrahimi, Erzsebet Kokovay, Alexander Pertsemlidis, Pedro A. F. Galante, Luiz O. F. Penalva Simple Summary miRNAs function as critical regulators of gene expression and have been defined as …

Nature Communications: Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells (Pertsemlidis)

November 16, 2020

Justin B. Moroney, Anusha Vasudev, Alexander Pertsemlidis, Hong Zan & Paolo Casali Abstract Memory B cells (MBCs) are long-lived and produce high-affinity, generally, class-switched antibodies. Here, we use a multiparameter approach involving CD27 …

Alexander Pertsemlidis, PhD Co-Awarded National Science Foundation Grant.

August 20, 2020

PI: Leonidas Bleris, PhD                       Co-PI: Alexander Pertsemlidis, PhD (UT Dallas)                                              (UT Health San Antonio) PROJECT SUMMARY Collaborative Research: Unraveling extracellular microRNA communication O …

Molecular Cancer Research: ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state

January 1, 2020

Adam Kosti, Liqin Du, Haridha Shivram, Mei Qiao, Suzanne Burns, Juan Gabriel Garcia, Alexander Pertsemlidis, Vishwanath R Iyer, Erzsebet Kokovay, Luiz OF Penalva 13-Cis-retinoic acid (RA) is typically used in postremission maintenance therapy in patien …

International Journal of Cancer: GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma

October 17, 2019

Manish Charan,  Piyush Dravid, Maren Cam, Anthony Audino, Amy C. Gross, Michael A. Arnold, Ryan D. Roberts, Timothy P. Cripe, Alexander Pertsemlidis, Peter J. Houghton, Hakan Cam Abstract Ewing sarcoma (EWS) is the second most common and aggressive typ …

Molecular Therapy – Oncolytics: The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5

September 27, 2019

Author links open overlay panelXiaojie Yu126, Yiqiang Zhang1, Binggen Wu13, Jonathan M.Kurie4, Alexander Pertsemlidis125 Chemoresistance and metastasis are the major reasons for non-small cell lung cancer (NSCLC) treatment failure and patient deaths. W …

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