Greehey CCRI Archives
YouTube: Experimental Biology TV, WebsEdgeMedicine
April 4, 2019https://www.youtube.com/watch?v=iWUUaz6A6Mo&t=92s “Cancers in children are rare, and the genetics and epigenetic causes are very different from those of adults. Consequently, the study of the etiology and potential therapies for these tumors requir …
BMC Medical Genomics: Predicting drug response of tumors from integrated genomic profiles by deep neural networks
January 31, 2019Yu-Chiao Chiu, Hung-I Harry Chen, Tinghe Zhang, Songyao Zhang, Aparna Gorthi, Li-Ju Wang, Yufei Huang & Yidong Chen Abstract Background The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insig …
Alex’s Lemonade Stand: The Crazy 8 Initiative Topics & Teams
October 1, 2018ALSF launched the Crazy 8 Initiative to detail roadmaps toward cures for specific, hard-to-treat childhood cancers. This collaborative effort kicked off in the fall of 2018 with a meeting that brought together more than 90 top scientists from around th …
Cancer Letters: Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells
July 1, 2018AlfeuZanotto-Filhoac SubapriyaRajamanickama EvaLoranca V. Pragathi Masamsettia AparnaGorthiab July CarolinaRomeroab SonalTonapiab Rosangela Mayer Gonçalvesc Robert L.Reddickd RaymondBenavidese JohnKuhnde YidongChenf Alexander J.R.Bishopab A …
Molecular & Cellular Oncology: Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage response
May 29, 2018Technology Networks: Link Discovered Between BRCA1 Protein and Aggressive Pediatric Cancer
March 8, 2018Scientists with the Greehey Children’s Cancer Research Institute at UT Health San Antonio have discovered a surprising connection between a breast cancer protein, BRCA1, and pediatric cancer called Ewing sarcoma. Their findings, reported March 7 in the …
UT Health SA Newsroom: Greehey Institute team finds link between BRCA1 and Ewing sarcoma
March 7, 2018A mutant oncogene in Ewing traps BRCA1 and prevents it from repairing genetic damage. Scientists with the Greehey Children’s Cancer Research Institute at UT Health San Antonio have discovered a surprising connection between a breast cancer protein, BRC …
EurekAlert: Greehey Institute team finds link between BRCA1 and Ewing sarcoma
March 7, 2018Scientists with the Greehey Children’s Cancer Research Institute at UT Health San Antonio have discovered a surprising connection between a breast cancer protein, BRCA1, and a pediatric cancer called Ewing sarcoma. Their findings, reported March 7 in t …
Life Extension Advocacy Foundation: Greehey Institute team finds link between BRCA1 and Ewing sarcoma
March 7, 2018Scientists with the Greehey Children’s Cancer Research Institute at UT Health San Antonio have discovered a surprising connection between a breast cancer protein, BRCA1, and a pediatric cancer called Ewing sarcoma. Their findings, reported March 7 in t …
Nature: EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
March 7, 2018Aparna Gorthi, July Carolina Romero, Eva Loranc, Lin Cao, Liesl A. Lawrence, Elicia Goodale, Amanda Balboni Iniguez, Xavier Bernard, V. Pragathi Masamsetti, Sydney Roston, Elizabeth R. Lawlor, Jeffrey A. Toretsky, Kimberly Stegmaier, Stephen L. Lessnic …