Dr. Yogesh Gupta, PhD Selected to Receive the Graduate Mentor of the Year Award at the 2025 GSBS Convocation Ceremony
Dr. Yogesh Gupta, Ph.D. Graduate Mentor of the Year Award Recipient Dr. Robert Svatek, M.D., M.S.C.I. Graduate Mentor of the Year Award Recipient We are thrilled to announce that Dr. Yogesh Gupta, Ph.D., and Dr. Robert Svatek, M.D., M.S.C.I., are the r …
Journal of Clinical Investigation: Efficacy and safety of a therapeutic humanized FSH–blocking antibody in obesity and Alzheimer’s disease models (Gupta)
July 30, 2025Anusha R. Pallapati,1 Funda Korkmaz,1 Satish Rojekar,1 Steven Sims,1 Anurag Misra,2 Judit Gimenez–Roig,1 Aishwarya Gangadhar,1 Victoria Laurencin,1 Anissa Gumerova,1 Uliana Cheliadinova,1 Farhath Sultana,1 Darya Vasilyeva,1 Liam Cullen,1 Jonathan Schue …
Structure: Structural insights into the assembly and regulation of 2′-O RNA methylation by SARS-CoV-2 nsp16/nsp10 (Gupta Lab)
April 14, 2025Anurag Misra 1 2, R. Rahisuddin 1 2, Manish Parihar 1, Shailee Arya 1, Thiruselvam Viswanathan 1 2, Nathaniel Jackson 3, Shan Qi 1 2, Siu-Hong Chan 4, Reuben S. Harris 2 5, Luis Martinez-Sobrido 3, Yogesh K. Gupta 1 2 6 Highlights SARS-CoV-2 nsp16/nsp1 …
Texas Public Radio: Science & Medicine: Sabotaging the molecular engines of some pediatric cancers (Gupta)
February 24, 2025Ewing sarcoma and rhabdomyosarcoma are cancers that overwhelmingly impact children. They’re soft tissue cancers that are thankfully rare because treatment options are limited, according to pediatric cancer researcher Yogesh Gupta, PhD, an associate pro …
ELife: Structure of METTL3-METTL14 with an m6A nucleotide reveals insights into m6A conversion and sensing (Rao, Gupta, et al)
February 11, 2025Abstract The nuclear METTL3-METTL14 transfers a methyl group from SAM to convert the N6 of adenosine (A) in RNA to m6A and in ssDNA to 6mA. m6A marks are prevalent in eukaryotic mRNAs and lncRNAs and modulate their stability and fate in a context-depen …
Cell: Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation (Gupta Lab)
January 17, 2025Giuseppe Quarto1,12 ∙ Andrea Li Greci1,12 ∙ Martin Bizet1,12 ∙ Audrey Penning1 ∙ Irina Primac1 ∙ Frédéric Murisier1 ∙ Liliana Garcia-Martinez2 ∙ Rodrigo L. Borges2 ∙ Qingzeng Gao3,4 ∙ Pradeep K.R. Cingaram2 ∙ Emilie Calonne1 ∙ Bouchra Hassabi1 ∙ Céline …
Molecular Cancer Therapeutics: Abstract B016: RNA demethylase ALKBH5 drives medulloblastoma growth and progression (Rao, Chen, Gupta, & Houghton Labs)
November 18, 2024Panneerdoss Subbarayalu; Daisy Medina; Pitta Prabhakar; Shahad Abdulsahib; Saif Nirzhor; Desiree Denman; Santosh Timilsina; Deepika Singh; Phat Do; Krishna Evani; Dhiya Billa; Esha Reddy; Peter Houghton; Yogesh Gupta; Yidong Chen; Suryavathi Viswanadha …
Science Advances: IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHCII complexes (Gupta Lab)
July 17, 2024ZHIJUN QIU JIHANE KHALIFE, PURUSHOTH ETHIRAJ CARINE JAAFAR, AN-PING LIN, KENNETH N. HOLDER, JACOB P. RITTER, LILLY CHIOU GABRIELA HUELGAS-MORALES SADIA ASLAM, ZHAO ZHANG ZHIJIE LIU SHA …
Yogesh Gupta, PhD, to Receive Grant from William and Ella Owens Medical Research Foundation to Study “Deciphering BAF Assembly for Pediatric Cancer Therapy”
June 17, 2024Deciphering BAF Assembly for Pediatric Cancer Therapy Synopsis: The adenosine triphosphate (ATP) dependent multi-subunit assemblies such as (BRG1/BRM-associated factors) complexes utilize ATP hydrolysis energy to reorganize chromatin architecture and f …
Molecular Cell: SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer (Gupta Lab)
January 3, 2024Hai-Li Ma 1 14, Martin Bizet 1 14, Christelle Soares Da Costa 1 14, Frédéric Murisier 1, Eric James de Bony 1 8, Meng-Ke Wang 2, Akihide Yoshimi 3 9, Kuan-Ting Lin 7, Kristin M. Riching 4, Xing Wang 2, John I. Beckman 5, Shailee Arya 5, Nathalie Droin …
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