Greehey CCRI Archives

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eLife: RNA binding to human METTL3-METTL14 restricts N6-deoxyadenosine methylation of DNA in vitro (Gupta Lab)

January 21, 2022

Shan Qi,  Javier Mota,  Siu-Hong Chan,  Johanna Villarreal,  Nan Dai,  Shailee Arya,  Robert A Hromas,  Manjeet K Rao,  Ivan R Corrêa Jr  Yogesh K Gupta  Abstract Methyltransferase like-3 (METTL3) and METTL14 complex transfer a methyl group from S-aden …


Yogesh Gupta PhD, to Receive UT Health SA “Rising Research Star” Award

October 25, 2021

Yogesh Gupta, PhD Assistant Professor Department of Biochemistry & Structural Biology​ Greehey Children’s Cancer Research Institute Last week, our very own Yogesh Gupta PhD, was recognized as one of the 2021 Joe R. and Teresa Lozano Long School of …


Yogesh Gupta Awarded, 5-year $3.0 million R01 NIH/NIAID Grant to Support His SARS-CoV-2 and RNA Methylation Work.

July 29, 2021

Dr. Yogesh Gupta was awarded a 5-year $3.0 million R01 NIH/NIAID (National Institute of Allergy and Infectious Diseases) grant to support his SARS-CoV-2 and RNA methylation work. ABSTRACT The massive global pandemic with high morbidity and mortality ma …


Nature Communications: Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase (Gupta)

June 29, 2021

Yogesh Gupta PhD Olga Rechkoblit, Robert E. Johnson, Yogesh K. Gupta, Louise Prakash, Satya Prakash & Aneel K. Aggarwal Abstract PrimPol is a human DNA polymerase-primase that localizes to mitochondria and nucleus and bypasses the major oxidative l …


Texas Public Radio: San Antonio Scientists Uncover One Way The COVID-19 Virus Hides From The Immune System (Gupta)

June 8, 2021

Texas Public Radio | By Bonnie Petrie Published June 7, 2021 at 3:47 PM CDT San Antonio scientists have uncovered one of the disguises used by SARS-CoV-2 — the virus that causes COVID-19 — to hide from the immune system. They are metal ions that everyo …


Texas Standard: We’ve been living with COVID-19 for a long, hard while now. (Gupta + collaborators)

June 7, 2021

Texas Standard Interview: “We’ve been living with COVID-19 for a long, hard while now. But we’re continuing to learn about it: what some Texas researchers say the virus does to hide in your body.”         Click on the image below to …


Nature Communications: Metal ions help COVID-19 virus to disguise itself (Gupta Lab)

June 2, 2021

SAN ANTONIO (June 2, 2021) — Scientists from The University of Texas Health Science Center at San Antonio (Gupta Lab) and other collaborators have discovered a mechanism by which SARS-CoV-2 exploits changes in metal ion concentrations to disguise itsel …


Shan Qi (Gupta Lab) Receives Hibbs Award for Research Execellence

May 25, 2021

Shan Qi, a 3rd year PhD student in Dr. Yogesh Gupta’s laboratory at Greehey CCRI, received the prestigious Hibbs Award “for Research Excellence is a major award given annually to recognize exemplary achievement and research excellence to a student enro …


Current Exchange: CSHL’s COVID/SARS CoV2 Rapid Research Meeting Reports V (Gupta)

May 18, 2021

Excerpt from “CSHL’s COVID/SARS CoV2 Rapid Research Meeting Reports V” Structural biology, molecular biology, and immunology As with the previous two meetings, this one was broken up into sections by topic and the first up was “Host-virus Interactions/ …