Greehey CCRI News & Events Archive

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Human Mutation: Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype-phenotype study in neurofibromatosis type 1

October 8, 2019

Magdalena Koczkowska 1, Tom Callens 1, Yunjia Chen 1, Alicia Gomes 1, Alesha D Hicks 1, Angela Sharp 1, Eric Johns 1, Kim Armfield Uhas 2, Linlea Armstrong 3, Katherine Armstrong Bosanko 4, Dusica Babovic-Vuksanovic 5, Laura Baker 6, Donald G Basel 7,  …


Review article “Challenges and Opportunities for Childhood Cancer Drug Development” co-authored by Drs Kurmasheva and Houghton

October 3, 2019

The review article “Challenges and Opportunities for Childhood Cancer Drug Development” co-authored by Raushan Kurmasheva, PhD and Peter Houghton, PhD has just been published.


Pharmacology Reviews: Challenges and Opportunities for Childhood Cancer Drug Development

October 1, 2019

Peter J Houghton 1, Raushan T Kurmasheva 2 Abstract Cancer in children is rare with approximately 15,700 new cases diagnosed in the United States annually. Through the use of multimodality therapy (surgery, radiation therapy, and aggressive chemotherap …


Cancer Research: Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma

October 1, 2019

Xiaolong Li 1, Emmanuel Martinez-Ledesma 1 2, Chen Zhang 1, Feng Gao 1, Siyuan Zheng 1, Jie Ding 1, Shaofang Wu 1, Nghi Nguyen 3, Stephan C Clifford 3, Patrick Y Wen 4, Keith L Ligon 4, W K Alfred Yung 1, Dimpy Koul 5 Abstract PI3K-targeting therapy re …


WEBINAR: Childhood Cancer Survivorship, Transitioning to Adulthood (Aune Lab)

September 27, 2019

REPOST from September 25th webinar originally broadcasted, September 25th, 2019 Childhood cancer advocates, families, researchers, and survivors are invited to join us for this Childhood Cancer Awareness Month event. We’ll have a robust discussion abou …


Molecular Therapy – Oncolytics: The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5

September 27, 2019

Author links open overlay panelXiaojie Yu126, Yiqiang Zhang1, Binggen Wu13, Jonathan M.Kurie4, Alexander Pertsemlidis125 Chemoresistance and metastasis are the major reasons for non-small cell lung cancer (NSCLC) treatment failure and patient deaths. W …


KENS5: UT Health working to fight children’s cancer with Hyundai Hope on Wheels grant (Houghton, Aune, Ignatius mention)

September 24, 2019

UT Health working to fight children’s cancer with Hyundai Hope on Wheels grant To help in the fight against pediatric cancer, Hyundai Hope on Wheels presented two grants totaling $500,000 to UT Health San Antonio. SAN ANTONIO — UT Health San Antonio is …


BioSpace: Hyundai Hope On Wheels Presents UT Health San Antonio With Hyundai Young Investigator And Scholar Hope Grant Totaling A Combined $500,000 To Support Pediatric Cancer Research (Aune & Ignatius Labs)

September 23, 2019

Hyundai Hope On Wheels® (HHOW), a 501(c)(3) non-profit organization supported by Hyundai and its U.S. dealers, announces $500,000 Hyundai Young Investigator and Scholar Hope Grant to UT Health San Antonio to continue its long-standing fight against ped …


Yahoo Finance: Hyundai Hope On Wheels Presents UT Health San Antonio With Hyundai Young Investigator And Scholar Hope Grant Totaling A Combined $500,000 To Support Pediatric Cancer Research

September 23, 2019


Developmental Cell: CENP-A Ubiquitylation Is Indispensable to Cell Viability

September 23, 2019

Summary CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity, but how CENP-A is deposited at the centromere remains obscure. We previously reported that CENP-A K124 ubiquitylation, mediated by the CUL4A- …


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