Greehey CCRI Archives
Molecular Cancer Therapeutics: Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis and Tumor Regression in H/NRAS Q61X-mutant Rhabdomyosarcoma (Houghton, Chen, Ignatius, Vaseva)
November 8, 2021Natalia Garcia, Vanessa Del Pozo, Marielle E. Yohe, Craig M. Goodwin, Terry J Shackleford, Long Wang, Kunal Baxi, Yidong Chen, Anna T Rogojina, Sara M. Zimmerman, Cody J. Peer, William D. Figg, Myron S. Ignatius, Kris C Wood, Peter J. Houghton, and Ang …
Communications Biology: LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer (Chen)
November 1, 2021Mengxing Li, Suryavathi Viswanadhapalli, Bindu Santhamma, Uday P. Pratap, Yiliao Luo, Junhao Liu, Kristin A. Altwegg, Weiwei Tang, Zexuan Liu, Xiaonan Li, Behnam Ebrahimi, Hui Yan, Yi Zou, Swapna Konda, Gangadhara R. Sareddy, Zhenming Xu, Yidong Chen, …
Cancer Letters: KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer (Lai & Chen Labs)
October 28, 2021Prabhakar PittaVenkataa1 YihongChenab1 SalvadorAlejoa YiHeab Bridgitte E.Palaciosa IlannaLoeffela JunhaoLiuacUday P.Pratapa GabrielleGraya Sureshkumar MulampurathAchuthan Pillaia YiZoud ZhaoLaideT akayoshiSuzukif SuryavathiViswanadhapallia SrinathPalak …
Request for Applications – Pilot Projects, 2021 Greehey CCRI Translational Science Award,
October 27, 2021Deadlines: Letter of Intent: Monday, November 15, 2021, 5 pm Full Proposal: 5 pm, Wednesday, December 15, 2021, 5 pm Overview The Greehey Children’s Cancer Research Institute (Greehey CCRI) is soliciting proposals for pilot project awards. The primary …
Molecular Cancer Research: GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer (Chen)
October 27, 2021Marieke Burleson, Janice J. Deng, Tai Qin, Thu Minh Duong, Yuqian Yan, Xiang Gu, Debodipta Das, Acarizia Easley, Michael A. Liss, P. Renee Yew, Roble Bedolla, Addanki Pratap Kumar, Tim Hui-Ming Huang, Yi Zou, Yidong Chen, Chun-Liang Chen, Haojie Huang, …
Free Radical Biology and Medicine: Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer (Bishop Lab)
October 26, 2021MarinaDelgoboa Rosângela MayerGonçalvesag Marco AntônioDelazerib MarceloFalchettia AlessandroZandonáb RaquelNascimento das Nevesa KarolineAlmeidaa Adriane CristinaFagundesa Daniel PensGelainc João IsidroFracassod Guilherme Baroni deMacêdod L …
Yogesh Gupta PhD, to Receive UT Health SA “Rising Research Star” Award
October 25, 2021Yogesh Gupta, PhD Assistant Professor Department of Biochemistry & Structural Biology Greehey Children’s Cancer Research Institute Last week, our very own Yogesh Gupta PhD, was recognized as one of the 2021 Joe R. and Teresa Lozano Long School of …
PIPETTE GAZETTE – Meet The Researcher: Aiola Stoja and her love for dogs, hiking and cancer research (Bishop Lab)
October 22, 2021While Aiola Stoja Payne was volunteering as an emergency medical technician (EMT), she learned about a new substance that was just being implemented in emergency medicine. She was taught that this substance was a powder that you put directly on the wou …
JoVE: Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins (Libich Lab)
October 13, 2021Courtney N. Johnson1, David S. Libich1 Abstract Intrinsically disordered proteins and intrinsically disordered regions within proteins make up a large and functionally significant part of the human proteome. The highly flexible nature of these sequence …
Frontiers in Molecular BioScience: Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes (Libich & Penalva labs)
October 13, 2021Antoine Baudin, 1 , 2 , † Alma K. Moreno-Romero, 1 , 2 Xiaoping Xu, 1 , 2 Emily E. Selig, 1 , 2 , † Luiz O. F. Penalva, 1 , 3 and David S. Libich 1 , 2 ,* † Abstract RNA binding proteins (RBPs) are essential for critical biological processes such as tr …