Greehey CCRI Archives

Filter results


 

Cell Reports: NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growthNELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth (Shiio, Houghton)

July 8, 2021

Panneerselvam Jayabal1, Fuchun Zhou1, Xiufen Lei1, XiuyeMa1, Barron Blackman1, Susan T.Weintraub23, Peter J.Houghton134, YuzuruShiio1235 Highlights • The autocrine signaling mediated by NELL2 maintains Ewing sarcoma cell growth • NELL2 signaling inhibi …


Dr. Houghton Co-Authors MDPI paper, “Dihydroartemisinin Inhibits mTORC1 Signaling by Activating the AMPK Pathway in Rhabdomyosarcoma Tumor Cells

July 2, 2021

Authored by: Jun Luo, Yoshinobu Odaka, Zhu Huang, Bing Cheng, Wang Liu, Lin Li, Chaowei Shang, Chao Zhang, Yang Wu, Yan Luo, Shengyong Yang, Peter J. Houghton, Xiaofeng Guo, Shile Huang Abstract Dihydroartemisinin (DHA), an anti-malarial drug, has been …


Nature Communications: Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase (Gupta)

June 29, 2021

Yogesh Gupta PhD Olga Rechkoblit, Robert E. Johnson, Yogesh K. Gupta, Louise Prakash, Satya Prakash & Aneel K. Aggarwal Abstract PrimPol is a human DNA polymerase-primase that localizes to mitochondria and nucleus and bypasses the major oxidative l …


Adam Kosti Successfully Defends PhD Dissertation (Penalva Lab)

June 21, 2021

Join us in congratulating Adam Kosti of the Penalva Lab for successfully defending his dissertation, “microRNA-Transcription Factor Networks in Gliomagenesis” last week. Mentor: Dr. Luiz Penalva Program: PhD in Integrated Biomedical Sciences Discipline …


Angelina Vaseva, PhD Presented 2021 Voelcker Pilot Award (Houghton Lab)

June 16, 2021

Angelina Vaseva, PhD Congratulations to Angelina Vaseva, PhD, research assistant professor at Greehey Children’s Cancer Research Institute and the Department of Molecular Medicine, on being presented a 2021 2021 Voelcker Pilot Award. Dr. Vaseva’s proje …


Pertsemlidis Lab Awarded American Lung Association Grant to Study “Identifying Exploitable Biomarkers of Lung Cancer Metastasis”

June 16, 2021

Greehey CCRI Principal Investigator, Alexander Pertsemlidis, PhD Abstract Rationale. Most cancer deaths are caused by metastatic disease, and the prevention of metastasis is a significant focus of clinical research. Aberrant expression of miRNAs has be …


St. Baldrick’s: Checking the Life-Threatening Box: A Survivor’s Update (Aune)

June 16, 2021

A childhood cancer survivor himself, Gregory J. Aune, MD, PhD, shares his personal experience and thoughts during National Cancer Survivor Month.           (Originally posted on Medium on May 19th, Dr. Aune graciously agreed to …


Greehey CCRI’s Genomic Sequencing Facility to Receive $600,000 NIH Grant to upgrade genomic sequencing capabilities (Lai Lab).

June 15, 2021

Dr. Zhao Lai, Director of the Genomic Sequencing Facility (GSF) at the Greehey Children’s Cancer Research Institute (Greehey CCRI) at UT Health San Antonio (UTHSA), has been awarded a $600,000 NIH grant to help purchase a new Illumina NovaSeq 6000. Thi …


Aging Cell: Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury (Chen Lab)

June 12, 2021

Hak Joo Lee, Andrew Donati, Denis Feliers, Yuyang Sun, Yanli Ding, Muniswamy Madesh, Adam B. Salmon, Yuji Ikeno, Corinna Ross, Christopher L. O’Connor, Wenjun Ju, Markus Bitzer, Yidong Chen, Goutam Ghosh Choudhury, Brij B. Singh, Kumar Sharma, Balakunt …


Texas Public Radio: San Antonio Scientists Uncover One Way The COVID-19 Virus Hides From The Immune System (Gupta)

June 8, 2021

Texas Public Radio | By Bonnie Petrie Published June 7, 2021 at 3:47 PM CDT San Antonio scientists have uncovered one of the disguises used by SARS-CoV-2 — the virus that causes COVID-19 — to hide from the immune system. They are metal ions that everyo …