Greehey CCRI Archives

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Current Exchange: CSHL’s COVID/SARS CoV2 Rapid Research Meeting Reports V (Gupta)

May 18, 2021

Excerpt from “CSHL’s COVID/SARS CoV2 Rapid Research Meeting Reports V” Structural biology, molecular biology, and immunology As with the previous two meetings, this one was broken up into sections by topic and the first up was “Host-virus Interactions/ …


NIH Grant Awarded to Collaborative Team to Eradicate Ewing Sarcoma (Aune)

May 13, 2021

Despite the breakthroughs being made in treating many cancers with less toxic, targeted, and immune-based therapies, Ewing sarcoma’s 40-year-old chemotherapy regimen remains a significant contributor to mortality and long-term cardiovascular complicati …


Yogesh Gupta,PhD., Invited to Present at Advanced Photon Source of Argonne National Laboratory, COVID-19 Workshop

May 13, 2021

Recently, Greehey CCRI principal investigator, Yogesh Gupta, PhD., was included as an invited speaker with prominent scientists from academia (Ian Wilson, Pamela Bjorkman, and others) and industry (Pfizer and Moderna) at a COVID-19 workshop organized b …


BMC Bioinformatics: CancerSiamese: one-shot learning for predicting primary and metastatic tumor types unseen during model training (Chen Lab)

May 13, 2021

Milad Mostavi, Yu-Chiao Chiu, Yidong Chen & Yufei Huang Abstract Background The state-of-the-art deep learning-based cancer type prediction can only predict cancer types whose samples are available during the training where the sample size is commo …


Journal of Clinical Medicine: Recent Developments in Nanomedicine for Pediatric Cancer (Kurmasheva)

April 30, 2021

by  Shicheng Yang 1, Mia Wallach 2 , Apurva Krishna 3, Raushan Kurmasheva 4,5,*,†  and Srinivas Sridhar 1,3,6,*,† Abstract Cancer is the second biggest cause of death in children in the US. With the development of chemotherapy, there has been a substan …


International Journal of Molecular Sciences: A Comprehensive Analysis into the Therapeutic Application of Natural Products as SIRT6 Modulators in Alzheimer’s Disease, Aging, Cancer, Inflammation, and Diabetes (Rao Lab)

April 30, 2021

Raushanara Akter 1, Afrina Afrose 1, Md Rashidur Rahman 2, Rakhi Chowdhury 1, Saif Shahriar Rahman Nirzhor 3, Rubayat Islam Khan 4, Md Tanvir Kabir 1 ABSTRACT Natural products have long been used as drugs to treat a wide array of human diseases. The le …


JCM: Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children’s Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force (Houghton)

April 30, 2021

by  Holly L. Pacenta 1,2, Wendy Allen-Rhoades,  3, David Langenau,  4, Peter J. Houghton,  5, Charles Keller 6, Christine M. Heske,  7 , Michael D. Deel,  8, Corinne M. Linardic,  8 , Jack F. Shern 7, Elizabeth Stewart,  9, Brian Turpin,  10, Douglas J …


A review article by Dr. Raushan Kurmasheva (senior author) gives an overview on recent developments in nanomedicine for pediatric cancer

April 30, 2021

Recent Developments in Nanomedicine for Pediatric Cancer by Shicheng Yang 1, Mia Wallach 2OrcID, Apurva Krishna 3, Raushan Kurmasheva 4,5,*,†OrcID and Srinivas Sridhar 1,3,6,*,† Abstract Cancer is the second biggest cause of death in children in the US …


BMC Bioinformatics – Correlation AnalyzeR: Functional Predictions from Gene Co-Expression Correlations (Bishop Lab)

April 21, 2021

Henry E. Miller, Alexander J. R. Bishop Abstract Background Co-expression correlations provide the ability to predict gene functionality within specific biological contexts, such as different tissue and disease conditions. However, current gene co-expr …


Frontiers in Molecular Biosciences: The Role of Human Centromeric RNA in Chromosome StabilityThe Role of Human Centromeric RNA in Chromosome Stability (Kitagawa Lab)

April 20, 2021

Introduction Accurate chromosome segregation is fundamental for cell division. Errors in this process can lead to chromosome instability, leading to aneuploidy, which is correlated with cancer (Zhu et al., 2011; Santaguida and Amon, 2015). The centrome …