Greehey CCRI News & Events Archive

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Science Signaling: Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies

September 26, 2017

Andrew M. Waters1,2, Irem Ozkan-Dagliyan3, Angelina V. Vaseva1,4, View ORCID ProfileNicole Fer2, Leslie A. Strathern2, View ORCID ProfileG. Aaron Hobbs1, View ORCID ProfileBasile Tessier-Cloutier5, View ORCID ProfileWilliam K. Gillette2, View ORCID Pro …


TEXAS PUBLIC RADIO: About 1,800 Children Die Of Cancer Every Year In The U.S.

September 25, 2017

More than 15,000 children and adolescents up to 19 years old will receive a cancer diagnosis this year, according to the National Cancer Institute. After accidents, cancer is the second leading cause of death in children ages 1 to 14. Conditions most c …


SA Express-News: Childhood cancer needs more attention

September 24, 2017

September is Childhood Cancer Awareness Month. Many citizens in our community may not realize that San Antonio is home to the Greehey Children’s Cancer Research Institute — the largest freestanding pediatric cancer research facility in Texas and one of …


Cancer Knowledge Network: We Must Consider New Strategies to Deliver Health Care to Childhood Cancer Survivors

September 21, 2017

 The Lancet: The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE).  Researchers at St. Jude Children’s Research Hospital reported data collected retrospectively through the St. Jude Life …


NIH: Searching for Less-Toxic Cancer Treatments for Kids (Aune Lab)

September 21, 2017

Advances in cancer treatment mean that today, more than 4 out of 5 children diagnosed with cancer will survive and remain cancer-free for at least 5 years after diagnosis. Many of these children will ultimately be considered cured of their cancer. Howe …


JoVE: Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

September 20, 2017

Helia N Sanchez 1, Tian Shen 2, Dawn Garcia 3, Zhao Lai 3, Paolo Casali 1, Hong Zan 4 Abstract Antibody responses are accomplished through several critical B cell-intrinsic processes, including somatic hypermutation (SHM), class-switch DNA recombinatio …


Nature Communications: Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells

September 19, 2017

Subbarayalu Panneerdoss, Suryavathi Viswanadhapalli, Nourhan Abdelfattah, Benjamin C. Onyeagucha, Santosh Timilsina, Tabrez A. Mohammad, Yidong Chen, Michael Drake, Kristiina Vuori, T. Rajendra Kumar & Manjeet K. Rao Abstract Phagocytic clearance o …


Oncotarget: Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die

September 12, 2017

Benjamin Onyeagucha1,2, Panneerdoss Subbarayalu1,2, Nourhan Abdelfattah1,2, Subapriya Rajamanickam1,2, Santosh Timilsina1,2, Rosa Guzman1, Carla Zeballos2, Vijay Eedunuri1,2, Sanjay Bansal1, Tabrez Mohammad2, Yidong Chen1,3, Ratna K. Vadlamudi4, and Ma …


Cancer Knowledge Network: The Financial Impact of Surviving Childhood Cancer

September 7, 2017

 Journal of Clinical Oncology — Financial Burden in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. Researchers evaluated self-reported household income data available through the Childhood Cancer Survivor Study (CCSS) …


Human Genetics: RNA processing as an alternative route to attack glioblastoma

September 1, 2017

Fabiana Marcelino Meliso, Christopher G Hubert, Pedro A Favoretto Galante, Luiz O Penalva Genomic analyses have become an important tool to identify new avenues for therapy. This is especially true for cancer types with extremely poor outcomes since ou …