Greehey CCRI Archives
Breast Cancer Research and Treatment: KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer
October 14, 2020Abstract Purpose Cancer stem cells (CSCs) are highly tumorigenic, spared by chemotherapy, sustain tumor growth, and are implicated in tumor recurrence after conventional therapies in triple-negative breast cancer (TNBC). Lysine-specific histone demethy …
Pipette Gazette: Trevi Mancilla First Author Publication in PLOS One About The Significance Of Non-Cardiomyocyte Cells (Aune Lab)
September 30, 2020Trevi Mancilla, a student in the South Texas Medical Scientist Training Program, has published a first-author publication in PLOS ONE. The title is “Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts.” Her mentor is Dr. Greg Aune. …
Cardiovascular Business: Chemotherapy could be damaging children’s heart cells, leading to problems later in life (Aune)
September 30, 2020Undergoing chemotherapy can have a negative impact on the cells responsible for repairing heart damage, according to a new study published in PLOS One. This may explain why 20% of children treated with anthracyclines go on to experience heart failure l …
Medical Xpress: Childhood Chemo Alters Heart’s Caretaker Cells, Study Finds (Aune Lab)
September 30, 2020by Will Sansom, UT Health San Antonio Cancer chemotherapy changes the function of cells that repair heart injury, researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) discovered. Twenty percent of children …
Scientific Reports: “Transcriptomic Sex Differences in Sensory Neuronal Populations of Mice”
September 23, 2020Jennifer Mecklenburg 1, Yi Zou 2, Andi Wangzhou 3, Dawn Garcia 2, Zhao Lai 2 4, Alexei V Tumanov 5, Gregory Dussor 3, Theodore J Price 3, Armen N Akopian 6 7 Abstract Many chronic pain conditions show sex differences in their epidemiology. This could b …
PLOS One: Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts (Aune)
September 22, 2020T. R. Mancilla, L. R. Davis, G. J. Aune Abstract Anthracyclines are the critical component in a majority of pediatric chemotherapy regimens due to their broad anticancer efficacy. Unfortunately, the vast majority of long-term childhood cancer survivor …
Scientific Reports: Transcriptomic sex differences in sensory neuronal populations of mice
September 17, 2020Jennifer Mecklenburg 1, Yi Zou 2, Andi Wangzhou 3, Dawn Garcia 2, Zhao Lai 2 4, Alexei V Tumanov 5, Gregory Dussor 3, Theodore J Price 3, Armen N Akopian 6 7 Abstract Many chronic pain conditions show sex differences in their epidemiology. This could b …
Raushan Kurmasheva, PhD, Part of Dmitri Ivanov, PhD, CPRIT Grant Team “Identifying and Optimizing Small Molecules for Drug Development.
September 8, 2020SOURCE: UT Health San Antonio Newsroom “The following are the additional researchers and their awards: Dmitri Ivanov, PhD, associate professor of biochemistry and structural biology, will receive an Individual Investigator Research Award for Cancer in …
Nucleic Acids Research: “PCAT: an Integrated Portal for Genomic and Preclinical Testing Data of Pediatric Cancer Patient-Derived Xenograft Models” in Oxford Academic (multiple faculty and researchers)
September 8, 2020Juechen Yang, Qilin Li, Nighat Noureen (Greehey CCRI, Zheng Lab), Yanbing Fang, Raushan Kurmasheva (Greehey CCRI, Kurmasheva Lab), Peter J Houghton (Greehey CCRI, Houghton Lab), Xiaojing Wang (Greehey CCRI, Wang Lab), Siyuan Zheng (Greehey CCRI, Zheng …
Ignatius Lab and Team “GCCRI Goes the Extra Mile” Organizing Local Alex’s Lemonade Stand “Million Mile” Virtual Event
September 3, 2020It’s that time of year again where we tell everyone what we do. We also remember the children with cancer and know your research will make a difference. Join us again this year for The Million Mile this September to raise awareness for Childhood Cancer …