Greehey CCRI News & Events Archive

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The American Journal of Pathology: Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit

September 1, 2016

The conserved RNA-binding protein Musashi1 (MSI1) has been characterized as a stem cell marker, controlling the balance between self-renewal and differentiation and as a key oncogenic factor in numerous solid tumors, including glioblastoma. To explore …


The American Journal of Pathology: Musashi1 impacts radio-resistance in glioblastoma by controlling DNA-protein kinase catalytic subunit

September 1, 2016

Patricia Rosa de Araujo, Aparna Gorthi, Acarizia E da Silva, Sonal S Tonapi, Dat T Vo, Suzanne C Burns, Mei Qiao, Philip J Uren, Zhi-Min Yuan, Alexander JR Bishop, Luiz OF Penalva The conserved RNA-binding protein Musashi1 (MSI1) has been characterized …


UT Health SA Newsroom: Health Science Center, UTSA gain $4.6 million for cancer research

August 25, 2016

The Center for Innovative Drug Discovery (CIDD), a joint program of the UT Health Science Center San Antonio and The University of Texas at San Antonio (UTSA), is receiving a $4,598,728 grant from the Cancer Prevention & Research Institute of Texas …


BMC Genomics: Detection of high variability in gene expression from single-cell RNA-seq profiling

August 22, 2016

Hung-I Harry Chen, Yufang Jin, Yufei Huang & Yidong Chen Abstract Background The advancement of the next-generation sequencing technology enables mapping gene expression at the single-cell level, capable of tracking cell heterogeneity and determina …


BMC Genomics: A hierarchical model for clustering m6A methylation peaks in MeRIP-seq data

August 22, 2016

Xiaodong Cui, Jia Meng, Shaowu Zhang, Manjeet K. Rao, Yidong Chen & Yufei Huang Abstract Background The recent advent of the state-of-art high throughput sequencing technology, known as Methylated RNA Immunoprecipitation combined with RNA sequencin …


BMC Genomics: CrossLink: a novel method for cross-condition classification of cancer subtypes

August 22, 2016

Chifeng Ma, Konduru S. Sastry, Mario Flore, Salah Gehani, Issam Al-Bozom, Yusheng Feng, Erchin Serpedin, Lotfi Chouchane, Yidong Chen & Yufei Huang Abstract Background We considered the prediction of cancer classes (e.g. subtypes) using patient gen …


BMC Genomics: MBDDiff: an R package designed specifically for processing MBDcap-seq datasets

August 18, 2016

Yuanhang Liu,  Desiree Wilson,  Robin J. Leach   Yidong Chen  Abstract Background Since its initial discovery in 1975, DNA methylation has been intensively studied and shown to be involved in various biological processes, such as development, aging, an …


San Antonio Report: Commentary: Are Questions More Powerful Than Answers?

July 23, 2016

In the afternoon, the students had an opportunity to meet with Dr. Alexander Pertsemlidis, associate professor of pediatrics, hematology, and oncology at the Greehey Children’s Cancer Research Institute at the University of Texas Health Science Center. …


San Antonio Business Journal: SA biotech company and Health Science Center to use the power of collaboration to combat cancer

July 13, 2016

One of San Antonio’s more promising bioscience companies, bioAffinity Technologies Inc., has locked up a key deal, renewing its collaborative agreement with the University of Texas Health Science Center at San Antonio. The extension will allow the two …


SA Business Journal: Cancer money to boost local pediatric research

July 3, 2016

The Cancer Prevention & Research Institute of Texas has awarded nearly $11 million to the University of Texas Health Science Center at San Antonio in its latest funding round. That award includes $5 million to help establish the Texas Pediatric Pat …