Greehey CCRI News & Events Archive

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National Coalition for Cancer Survivorship: Guest Post: Oncologist and Cancer Survivor Greg Aune Talks Multi-Disciplinary Care

July 31, 2015

The Importance of Multidisciplinary Survivorship Care and Research Post by Greg Aune, MD, PhD, Greehey Children’s Cancer Research Institute, Univ. of Texas Health Science Center at San Antonio Survivors of cancer are a growing population in the United …


BMC Genomics: Co-modulation analysis of gene regulation in breast cancer reveals complex interplay between ESR1 and ERBB2 genes

June 11, 2015

Yu-Chiao Chiu, Chin-Ting Wu, Tzu-Hung Hsiao, Yi-Pin Lai, Chuhsing Kate Hsiao, Yidong Chen & Eric Y Chuang Abstract Background Gene regulation is dynamic across cellular conditions and disease subtypes. From the aspect of regulation under modulation …


BMC Genomics: Education, collaboration, and innovation: intelligent biology and medicine in the era of big data

June 11, 2015

Jianhua Ruan, Victor Jin, Yufei Huang, Hua Xu, Jeremy S Edwards, Yidong Chen & Zhongming Zhao Abstract Here we present a summary of the 2014 International Conference on Intelligent Biology and Medicine (ICIBM 2014) and the editorial report of the s …


BMC Genomics: Differential expression analysis of RNA sequencing data by incorporating non-exonic mapped reads

June 11, 2015

Hung-I Harry Chen, Yuanhang Liu, Yi Zou, Zhao Lai, Devanand Sarkar, Yufei Huang & Yidong Chen Abstract Background RNA sequencing (RNA-seq) is a powerful tool for genome-wide expression profiling of biological samples with the advantage of high-thro …


RNA Biology: microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest

May 6, 2015

Zhenze ZhaoGreehey Children’s Cancer Research Institute; ,Xiuye Ma,Derek Sung,Monica Li,Adam Kosti,Gregory Lin,Yidong Chen,Alexander Pertsemlidis,Tzu-Hung Hsiao &Liqin Du Abstract microRNA-449a (miR-449a) has been identified to function as a tumor …


BMC Genomics: HEPeak: an HMM-based exome peak-finding package for RNA epigenome sequencing data

April 21, 2015

Xiaodong Cui, Jia Meng, Manjeet K Rao, Yidong Chen & Yufei Huang Abstract Background Methylated RNA Immunoprecipitation combined with RNA sequencing (MeRIP-seq) is revolutionizing the de novo study of RNA epigenomics at a higher resolution. However …


BMC Genomics: Parameter optimization for constructing competing endogenous RNA regulatory network in glioblastoma multiforme and other cancers

April 21, 2015

Yu-Chiao Chiu, Tzu-Hung Hsiao, Yidong Chen & Eric Y Chuang Abstract Background In addition to direct targeting and repressing mRNAs, recent studies reported that microRNAs (miRNAs) can bridge up an alternative layer of post-transcriptional gene reg …


New Phytologist: Genome scans reveal candidate domestication and improvement genes in cultivated sunflower, as well as post-domestication introgression with wild relatives

April 1, 2015

Gregory J Baute 1, Nolan C Kane, Christopher J Grassa, Zhao Lai, Loren H Rieseberg Abstract The development of modern crops typically involves both selection and hybridization, but to date, most studies have focused on the former. In the present study, …


IEEE Xplore: MeTDiff: A Novel Differential RNA Methylation Analysis for MeRIP-Seq Data

March 2, 2015

Lin Zhang; Jia Meng; Manjeet K. Rao; Yidong Chen; Yufei Huang Abstract: N6-Methyladenosine (m6A) transcriptome methylation is an exciting new research area that just captures the attention of the research community. We present in this paper, MeTDiff, a …


Texas Public Radio: The Source: President’s Precision Medicine Initiative Has San Antonio Connection

February 15, 2015

President Obama announced in his State of the Union Address and followed up with details in late January, a $215 million plan to better design drugs and therapies to work on individual patients rather than average ones. Precision medicine isn’t new, it …