Greehey CCRI News & Events Archive

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International Journal of Molecular Sciences (MDPI): Potential Relationship between Inadequate Response to DNA Damage and Development of Myelodysplastic Syndrome

January 5, 2015

Ting Zhou 1,2,Peishuai Chen 1,3,Jian Gu 3,Alexander J. R. Bishop 1,2,4,5,Linda M. Scott 6,Paul Hasty 4,5,7 and Vivienne I. Rebel 1,2,4,5,* Abstract Hematopoietic stem cells (HSCs) are responsible for the continuous regeneration of all types of blood ce …


Journal of Biological Chemistry: Hormone-induced and DNA Demethylation-induced Relief of a Tissue-specific and Developmentally Regulated Block in Transcriptional Elongation*

December 19, 2014

Abstract Genome-wide studies have revealed that genes commonly have a high density of RNA polymerase II just downstream of the transcription start site. This has raised the possibility that genes are commonly regulated by transcriptional elongation, bu …


American Journal of Physiology – Heart & Circulatory Physiology: The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure

November 15, 2014

Merry L. Lindsey, Richard A. Lange, Helen Parsons, Thomas Andrews, and Gregory J. Aune Abstract Since the modern era of cancer chemotherapy that began in the mid-1940s, survival rates for children afflicted with cancer have steadily improved from 10% t …


American Journal of Physiology: The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure

November 14, 2014

Abstract Since the modern era of cancer chemotherapy that began in the mid-1940s, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80% (60). Unfortunately, many long-term survivors of pedi …


BMC Bioinformatics: Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2013): Bioinformatics

November 6, 2014

Zijing Mao, Chifeng Ma, Tim H-M Huang, Yidong Chen & Yufei Huang Abstract DNA methylation is a common epigenetic marker that regulates gene expression. A robust and cost-effective way for measuring whole-genome methylation is Methyl-CpG binding dom …


Nucleic Acids Research: MeT-DB: a database of transcriptome methylation in mammalian cells

November 6, 2014

Hui Liu, Mario A Flores, Jia Meng, Lin Zhang, Xinyu Zhao, Manjeet K. Rao, Yidong Chen, Yufei Huang Abstract Methyltranscriptome is an exciting new area that studies the mechanisms and functions of methylation in transcripts. The MethylTranscriptome Dat …


Plant Physiology: De novo genome assembly of the economically important weed horseweed using integrated data from multiple sequencing platforms

November 1, 2014

Yanhui Peng 1, Zhao Lai 1, Thomas Lane 1, Madhugiri Nageswara-Rao 1, Miki Okada 1, Marie Jasieniuk 1, Henriette O’Geen 1, Ryan W Kim 1, R Douglas Sammons 1, Loren H Rieseberg 1, C Neal Stewart Jr 2 Erratum in Plant Physiol. 2014 Dec;166(4):2218 Abstrac …


Breast Cancer Research and Treatment: Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers

October 14, 2014

Xinglei Chai 1, Tara M Friebel, Christian F Singer, D Gareth Evans, Henry T Lynch, Claudine Isaacs, Judy E Garber, Susan L Neuhausen, Ellen Matloff, Rosalind Eeles, Nadine Tung, Jeffrey N Weitzel, Fergus J Couch, Peter J Hulick, Patricia A Ganz, Mary B …


AACO: Introducing the ACCO’s Newest Board Members

October 1, 2014

Welcome to Dr. Greg Aune and Mr. Clint Janson, ACCO’s Newest Board Members! The ACCO is pleased to introduce Dr. Greg Aune and Mr. Clint Janson as the newest members of our Board of Directors, our volunteer leadership group dedicated to guiding and pro …


Methods: A protocol for RNA methylation differential analysis with MeRIP-Seq data and exomePeak R/Bioconductor package

October 1, 2014

Author links open overlay panelJiaMenga,  ZhiliangLua,  HuiLiub,  LinZhangb,  ShaowuZhangc, YidongChende, Manjeet K.Raoef,  YufeiHuanggd Abstract Despite the prevalent studies of DNA/Chromatin-related epigenetics, such as, histone modifications and DNA …


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