Greehey CCRI Archives

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Clinical Cancer Research: Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling

December 1, 2018

Michele Dowless, Caitlin D. Lowery, Terry Shackleford, Matthew Renschler, Jennifer Stephens, Robert Flack, Wayne Blosser, Simone Gupta, Julie Stewart, Yue Webster, Jack Dempsey, Alle B. VanWye, Philip Ebert, Philip Iversen, Jonathan B. Olsen, Xueqian G …


Genome Biology: The proBAM and proBed standard formats: enabling a seamless integration of genomics and proteomics data

December 1, 2018

Gerben Menschaert, Xiaojing Wang, Andrew R Jones, Fawaz Ghali, David Fenyö, Volodimir Olexiouk, Bing Zhang, Eric W Deutsch, Tobias Ternent, Juan Antonio Vizcaíno On behalf of The Human Proteome Organization (HUPO) Proteomics Standards Initiative, we in …


International Journal of Cancer: Profiles of brain metastases: Prioritization of therapeutic targets

December 1, 2018

Sherise D Ferguson 1, Siyuan Zheng 2, Joanne Xiu 3, Shouhao Zhou 4, Mustafa Khasraw 5, Priscilla K Brastianos 6, Santosh Kesari 7, Jethro Hu 8, Jeremy Rudnick 8, Michael E Salacz 9, David Piccioni 10, Suyun Huang 1, Michael A Davies 11, Isabella C Glit …


RNA Biology: Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells

November 18, 2018

Caihong Yi,Guiming Li,Dmitri N. Ivanov,Zhonghua Wang,Mitzli X. Velasco,Greco Hernández,Soni Kaundal,Johanna Villarreal,Yogesh K. Gupta  ,Mei Qiao,Christopher G. Hubert,Matthew J. Hart &Luiz O.F. Penalva ABSTRACT RNA binding proteins have emerged as …


Cancer Research: Astrocyte Elevated Gene-1 Regulates Macrophage Activation in Hepatocellular Carcinogenesis

November 15, 2018

Chadia L Robertson 1, Rachel G Mendoza 1, Nidhi Jariwala 1, Mikhail Dozmorov 2 3, Nitai D Mukhopadhyay 2 3, Mark A Subler 1, Jolene J Windle 1 3, Zhao Lai 4, Paul B Fisher 1 3 5, Shobha Ghosh 6, Devanand Sarkar 7 3 5 Abstract Chronic inflammation is a …


EurekAlert: Tiny molecule has big effect in childhood brain tumor studies

November 7, 2018

Sometimes small things make the biggest difference. A new study by UT Health San Antonio researchers found that a molecule thousands of times smaller than a gene is able to kill medulloblastoma, the most common childhood brain cancer. This tiny molecul …


Science Daily: Tiny molecule has big effect in childhood brain tumor studies

November 7, 2018

Sometimes small things make the biggest difference. A new study by UT Health San Antonio researchers found that a molecule thousands of times smaller than a gene are able to kill medulloblastoma, the most common childhood brain cancer. This tiny molecu …


RNA Biology: Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells

November 2, 2018

Caihong Yi, Guiming Li, Dmitri N Ivanov, Zhonghua Wang, Mitzli X Velasco, Greco Hernández, Soni Kaundal, Johanna Villarreal, Yogesh K Gupta, Mei Qiao, Christopher G Hubert, Matthew J Hart, Luiz OF Penalva RNA binding proteins have emerged as critical o …


European Urology: Metabolic Biosynthesis Pathways Identified from Fecal Microbiome Associated with Prostate Cancer

November 1, 2018

Michael A Liss 1, James Robert White 2, Martin Goros 3, Jonathan Gelfond 3, Robin Leach 4, Teresa Johnson-Pais 4, Zhao Lai 5, Elizabeth Rourke 4, Joseph Basler 4, Donna Ankerst 4, Dimpy P Shah 3 Abstract Background: The fecal microbiome is associated w …


Nature Communications: MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma

October 31, 2018

Nourhan Abdelfattah, Subapriya Rajamanickam, Subbarayalu Panneerdoss, Santosh Timilsina, Pooja Yadav, Benjamin C. Onyeagucha, Michael Garcia, Ratna Vadlamudi, Yidong Chen, Andrew Brenner, Peter Houghton & Manjeet K. Rao Abstract Despite improvement …