Greehey CCRI Archives
Pediatric Hematology & Oncology: Circulating tumor DNA sequencing of pediatric solid and brain tumor patients: An institutional feasibility study (Tomlinson)
June 27, 2023Ross Mangum, Jacquelyn Reuther ,Koel Sen Baksi Ilavarasi Gandhi, Ryan C. Zabriskiec, Alva Recinos, , Robin Raesz-Martinez, Frank Y. Lin, Samara L. Potter, Andrew C. Sher, Stephen F. Kralik, Carrie A. Mohila, Murali M. Chintagumpala, Donna Muzny, Jianho …
Bioinformatics Advances: DepLink: an R Shiny app to systematically link genetic and pharmacologic dependencies of cancer (Zheng, Houghton, & Chen Labs)
June 27, 2023Tapsya Nayak, Li-Ju Wang, Michael Ning, Gabriela Rubannelsonkumar, Eric Jin, Siyuan Zheng, Peter J Houghton, Yufei Huang, Yu-Chiao Chiu, Yidong Chen Abstract Motivation Large-scale genetic and pharmacologic dependency maps are generated to reveal genet …
Nature: Structural Insights into BCDX2 Complex Function in Homologous Recombination (Sung Lab)
June 22, 2023Yashpal Rawal, Lijia Jia, Aviv Meir, Shuo Zhou, Hardeep Kaur, Eliza A. Ruben, Youngho Kwon, Kara A. Bernstein, Maria Jasin, Alexander B. Taylor, Sandeep Burma, Robert Hromas, Alexander V. Mazin, Weixing Zhao, Daohong Zhou, Elizabeth V. Wasmuth, Eric C. …
NAR Cancer: The 3D Chromatin Landscape of Rhabdomyosarcoma (Ignatius Lab)
June 16, 2023Meng Wang, Prethish Sreenivas, Benjamin D Sunkel, Long Wang, Myron Ignatius, Benjamin Z Stanton Abstract Rhabdomyosarcoma (RMS) is a pediatric soft tissue cancer with a lack of precision therapy options for patients. We hypothesized that with a gener …
Katsumi Kitagawa, Pharm.D., PhD, to Receive NIH Grant to study “The Role of EWSR1 at the Centromere.”
June 16, 2023Abstract Text The centromere is a unique chromosomal region that is essential for high-fidelity chromosome transmission during cell division. In mitosis, microtubules attached to the kinetochore help ensure the faithful segregation of sister chromatids …
Nature: Break-induced replication orchestrates resection-dependent template switching (Sung)
June 15, 2023Tianpeng Zhang, Yashpal Rawal, Haoyang Jiang, Youngho Kwon, Patrick Sung & Roger A. Greenberg Abstract Break-induced telomere synthesis (BITS) is a RAD51-independent form of break-induced replication that contributes to the alternative lengthening …
RNA Biology: The Paralogues MAGOH and MAGOHB are Oncogenic Factors in High-Grade Gliomas and Safeguard the Splicing of Cell Division and Cell Cycle Genes (Penalva Lab)
June 9, 2023Rodrigo A. S. Barreiro, Gabriela D. A. Guardia, Fabiana M. Meliso, Xiufen Lei, Wei-Qing Li, Andre Savio, Martin Fellermeyer, Helena B. Conceição, Rafael L. V. Mercuri, Tesha Landry, Mei Qiao, Lorea Blazquez, Jernej Ule, Luiz O.F. Penalva & Pedro A. …
Journal of Clinical Oncology: The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer (Aune Co-author)
June 5, 2023Joseph A. Flores-Toro , PhD1; Subhashini Jagu , PhD1; Gregory T. Armstrong, MD, MSCE2; David F. Arons, JD3; Gregory J. Aune, MD, PhD4; Stephen J. Chanock , MD1; Douglas S. Hawkins , MD5; Allison Heath , PhD6; Lee J. Helman , MD7; Katherine A. Jan …
Panneerdoss Subbarayalu, PhD, to receive NIH, NCI R21 Grant, “Targeting the RNA Modifying Enzyme ALKBH5 in Medulloblastoma
June 5, 2023Project Title: Targeting the RNA modifying enzyme ALKBH5 in Medulloblastoma Principal Investigator: Panneerdoss Subbarayalu Co-Investigators: Manjeet Rao, PhD, Andrew Brenner, MD, PhD., Peter Houghton, PhD. Funding Agency: National Institutes of Health …
ELife: Defining function of wild-type and three patient specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma (Ignatius Lab, Houghton Lab, Libich Lab, Chen, Tomlinson)
June 2, 2023Jiangfei Chen Kunal Baxi Amanda E Lipsitt Nicole Rae Hensch Long Wang Prethish Sreenivas Paulomi Modi Xiang Ru Zhao Antoine Baudin Daniel G Robledo Abhik Bandyopadhyay Aaron Sugalski Anil K Challa Dias Kurmashev Andrea R Gilbert Gail E Tomlinson Peter …