Greehey CCRI News & Events Archive

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Cancer Cell: Amplification of Distant Estrogen Response Elements Deregulates Target Genes Associated with Tamoxifen Resistance in Breast Cancer

August 12, 2013

Pei-YinHsu1  Hang-KaiHsu1  XunLan6  LiranJuan9  Pearlly S.Yan7  JadwigaLabanowska8  NylaHeerema8  Tzu-HungHsiao4  Yu-ChiaoChiu5  YidongChen34  YunlongLiu9  LangLi9RongLi1I  an M.Thompson2  Kenneth P.Nephew10  Zelton D.Sharp  1 Nameer B.Kirma1  Victor X …


Experimental Hematology: Myelodysplastic syndrome: An inability to appropriately respond to damaged DNA?

August 1, 2013

Author links open overlay panelTingZhouab PaulHastycde Christi A.Walterbdef Alexander J.R.Bishopabde Linda M.Scottg Vivienne I.Rebelabde Myelodysplastic syndrome (MDS) is considered a hematopoietic stem cell disease that is characterized by abnormal he …


Pediatric Blood & Cancer: Outcomes for patients with congenital hepatoblastoma

June 24, 2013

Angela D Trobaugh-Lotrario 1, Barbara H Chaiyachati, Rebecka L Meyers, Beate Häberle, Gail E Tomlinson, Howard M Katzenstein, Marcio H Malogolowkin, Dietrich von Schweinitz, Mark Krailo, James H Feusner Abstract Background: Congenital hepatoblastoma, d …


Bioinformatics: Exome-based analysis for RNA epigenome sequencing data

June 15, 2013

Jia Meng, Xiaodong Cui, Manjeet K. Rao, Yidong Chen, Yufei Huang Abstract Motivation: Fragmented RNA immunoprecipitation combined with RNA sequencing enabled the unbiased study of RNA epigenome at a near single-base resolution; however, unique features …


Echocardiography: Cardiac Assessment in Pediatric Mice: Strain Analysis as a Diagnostic Measurement

June 7, 2013

Thomas G. Andrews, M.Sc.,* Merry L. Lindsey, PhD,† Richard A. Lange, MD, M.B.A,‡ and Gregory J. Aune, MD, PhD§ Echocardiography is a robust tool for assessing cardiac function in both humans and laboratory animals. Conventional echocardiographic measur …


IEEE: Estimating Conditional Probabilities for the Detection of Unfavorable Copy Number Alterations in a Targeted Therapy

June 5, 2013

Fang-Han Hsu; Edward R. Dougherty; Yidong Chen; Erchin Serpedin Abstract: Emerging targeted therapies have shown benefits such as less toxicity and higher effectiveness in specific types of cancer treatment; however, the accessibility of these advantag …


Diabetes Journal: Enhanced NF-κB Activity Impairs Vascular Function Through PARP-1–, SP-1–, and COX-2–Dependent Mechanisms in Type 2 Diabetes

June 1, 2013

Modar Kassan1,2, Soo-Kyoung Choi1,  Maria Galán1,2, Alexander Bishop3, Kazuo Umezawa4, Mohamed Trebak5, Souad Belmadani2⇑ , and Khalid Matrougui1,2⇑ Abstract Type 2 diabetes (T2D) is associated with vascular dysfunction. We hypothesized that increased …


Cancer Epidemiology: Maternal pregnancy events and exposures and risk of hepatoblastoma: a Children’s Oncology Group (COG) study

June 1, 2013

Jessica R B Musselman 1, Michael K Georgieff, Julie A Ross, Gail E Tomlinson, James Feusner, Mark Krailo, Logan G Spector Abstract Background: Hepatoblastoma is a rare childhood liver cancer with an obscure etiology, however, it is potentially associat …


PLOS One: CMS: A Web-Based System for Visualization and Analysis of Genome-Wide Methylation Data of Human Cancers

April 22, 2013

Fei Gu ,Mark S. Doderer ,Yi-Wen Huang,Juan C. Roa,Paul J. Goodfellow,E. Lynette Kizer,Tim H. M. Huang ,Yidong Chen  Abstract Background DNA methylation of promoter CpG islands is associated with gene suppression, and its unique genome-wide profiles hav …


The New Phytologist: Transcriptome divergence between introduced and native populations of Canada thistle, Cirsium arvense

April 13, 2013

Alessia Guggisberg 1, Zhao Lai, Jie Huang, Loren H Rieseberg Abstract Introduced plants may quickly evolve new adaptive traits upon their introduction. Canada thistle (Cirsium arvense – Cardueae, Asteraceae) is one of the worst invasive weeds worldwide …


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