Greehey CCRI News & Events Archive

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Proteome Science: Bayesian non-negative factor analysis for reconstructing transcription factor mediated regulatory networks

October 14, 2011

Jia Meng, Jianqiu (Michelle) Zhang, Yidong Chen & Yufei Huang Abstract Background Transcriptional regulation by a transcription factor (TF) controls the time and abundance of mRNA transcription. Due to the limitation of current proteomics technolog …


BMC Research Notes: A model-based circular binary segmentation algorithm for the analysis of array CGH data

October 10, 2011

Fang-Han Hsu, Hung-I H Chen, Mong-Hsun Tsai, Liang-Chuan Lai, Chi-Cheng Huang, Shih-Hsin Tu, Eric Y Chuang & Yidong Chen Abstract Background Circular Binary Segmentation (CBS) is a permutation-based algorithm for array Comparative Genomic Hybridiza …


BMC Cancer: Activating mutation in MET oncogene in familial colorectal cancer

October 4, 2011

Deborah W Neklason 1, Michelle W Done, Nykole R Sargent, Ann G Schwartz, Hoda Anton-Culver, Constance A Griffin, Dennis J Ahnen, Joellen M Schildkraut, Gail E Tomlinson, Louise C Strong, Alexander R Miller, Jill E Stopfer, Randall W Burt Abstract Backg …


Carcinogenesis: Candidate gene association analysis of acute lymphoblastic leukemia identifies new susceptibility locus at 11p15 (LMO1)

September 21, 2011

Joke Beuten 1, Jonathan A L Gelfond, Duangjai Piwkham, Brad H Pollock, Naomi J Winick, Anderson B Collier 3rd, Gail E Tomlinson Abstract To determine the contribution of susceptibility loci in explaining the genetic basis of acute lymphoblastic leukemi …


Molecular & Cellular Biology: A Conditional Mouse Model for Measuring the Frequency of Homologous Recombination Events In Vivo in the Absence of Essential Genes

August 10, 2011

Adam D. Brown, Alison B. Claybon, Alexander J. R. Bishop ABSTRACT The ability to detect and repair DNA damage is crucial to the prevention of various diseases. The loss of function of genes involved in these processes is known to result in significant …


Cancer Epidemiology Biomarkers & Prevevention: Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers

August 1, 2011

Susan L Neuhausen 1, Sean Brummel, Yuan Chun Ding, Linda Steele, Katherine L Nathanson, Susan Domchek, Timothy R Rebbeck, Christian F Singer, Georg Pfeiler, Henry T Lynch, Judy E Garber, Fergus Couch, Jeffrey N Weitzel, Andrew Godwin, Steven A Narod, P …


Cancer Research: Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes

July 28, 2011

Timothy R Rebbeck 1, Nandita Mitra, Susan M Domchek, Fei Wan, Tara M Friebel, Teo V Tran, Christian F Singer, Muy-Kheng Maria Tea, Joanne L Blum, Nadine Tung, Olufunmilayo I Olopade, Jeffrey N Weitzel, Henry T Lynch, Carrie L Snyder, Judy E Garber, Ant …


UT Health SA Newsroom: CPRIT honors San Antonio cancer investigators

July 15, 2011

A ceremony marking Cancer Prevention and Research Institute of Texas’ awards totaling almost $13 million in cancer research dollars to San Antonio health and academic institutions. UT Health Science Center primary award – multi-institutional, multi-inv …


JAMA Network: Clinically relevant changes in family history of cancer over time

July 13, 2011

Argyrios Ziogas 1, Nora K Horick, Anita Y Kinney, Jan T Lowery, Susan M Domchek, Claudine Isaacs, Constance A Griffin, Patricia G Moorman, Karen L Edwards, Deirdre A Hill, Jonathan S Berg, Gail E Tomlinson, Hoda Anton-Culver, Louise C Strong, Carol H K …


Cancer Epidemiology Biomarkers & Prevention: Polymorphisms in CYP1A1 and ethnic-specific susceptibility to acute lymphoblastic leukemia in children.

July 1, 2011

Ryan M Swinney 1, Joke Beuten, Anderson B Collier 3rd, Tina T-L Chen, Naomi J Winick, Brad H Pollock, Gail E Tomlinson Abstract Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. The U.S. Surveillance Epidemiology a …


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