Greehey CCRI Archives
Cell Reports: EWSR1 Maintains Centromere Identity (Kitagawa & Houghton labs)
May 30, 2023Risa Kitagawa 1, Yohei Niikura 1 2, Argentina Becker 1 3, Peter J. Houghton 1, Katsumi Kitagawa 1 4 Highlights EWSR1 is required to maintain CENP-A at the centromere in interphase cells EWSR1 binds to CENP-A through the SYGQ2 region, important for phas …
Clinical Cancer Research: Phase II Investigation of TVB-2640 (Denifanstat)with Bevacizumabin Patients with First Relapse High-Grade Astrocytoma (Chen)
May 24, 2023William Kelly 1, Adolfo Enrique Diaz Duque 1,Joel Michalek 2, Brandon Konkel 3,L aura Caflisch 3, Yidong Chen 2,Sarath Chand Pathuri 1,Vinu Madhusudanannair-Kunnuparampil 4, John Floyd II 5,and Andrew Brenner 1 ABSTRACT Purpose: Glioblastoma represents …
Biomolecules: Enhancing the Conformational Stability of the cl-Par-4 Tumor Suppressor via Site-Directed Mutagenesis (Libich Lab)
May 17, 2023Samjhana Pandey Krishna K. Raut Andrea M. Clark Antoine Baudin Lamya Djemri David S. Libich Komala Ponniah Steven M. Pascal Abstract Intrinsically disordered proteins play important roles in cell signaling, and dysregulation of these proteins is as …
Cells: The RNA Demethylase ALKBH5 Maintains Endoplasmic Reticulum Homeostasis by Regulating UPR, Autophagy, and Mitochondrial Function (Chen, Sung, & Rao Labs)
May 17, 2023Panneerdoss Subbarayalu Pooja Yadav Santosh Timilsina Daisy Medina Kunal Baxi Robert Hromas Ratna K. Vadlamudi Yidong Chen Patrick Sung Manjeet K. Rao Abstract Eukaryotic cells maintain cellular fitness by employing well-coordinated and evolutionarily …
Paulomi Modi (Ignatius Lab) Recognized as 2023 Presidential Ambassador Scholar
May 8, 2023Ambassadors from left to right: Gina Baxter (SHP), Avani Ved (SON), Paulomi Modi (GSBS), Alejandra Garcia (LSOM) and Tyler Childs (SOD) Paulomi Modi is a second-year PhD student in the Integrated Biomedical Sciences program at the Graduate School of Bi …
Thrombosis Research: A cohort study on blood coagulation in childhood cancer survivors (Aune)
May 5, 2023Andrew D. Meyer a, Tyler B. Hughes a, Anjana R. Rishmawi a, Patty Heard a, Shafqat Shah b, Gregory J. Aune b c Highlights Anticoagulants decrease thrombotic events in adults receiving cance …
Advanced Science: Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1-EEF1A1 Axis (Bishop)
April 26, 2023Mingli Li, Lu Yang, Anthony K. N. Chan, Sheela Pangeni Pokharel, Qiao Liu, Nicole Mattson, Xiaobao Xu, Wen-Han Chang, Kazuya Miyashita, Priyanka Singh, Leisi Zhang, Maggie Li, Jun Wu, Jinhui Wang, Bryan Chen, Lai N. Chan, Jaewoong Lee, Xu Hannah Zhang, …
Angelina Vaseva, PhD to Receive Department of Defense Neurofibromatosis Research Program New Investigator Award
April 25, 2023Abstract Neurofibromatosis type 1 (NF1) -associated malignant peripheral nerve sheath tumor is the leading cause of death in patients with NF1 syndrome. It is a highly aggressive soft-tissue sarcoma with very limited therapy options due to resistance t …
PLOS ONE: Childhood cancer survival in the highly vulnerable population of South Texas: A cohort study (Tomlinson Lab)
April 24, 2023Shenghui Wu , Yanning Liu, Melanie Williams, Christine Aguilar, Amelie G. Ramirez, Ruben Mesa, Gail E. Tomlinson Abstract This study examines childhood cancer survival rates and prognostic factors related to survival in the majority Hispanic population …
PLOS GENETICS: Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent (Chen)
April 6, 2023Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer Abstract Defective ribosome biogenesis (RiBi) underlies a group of clinically diverse human diseases collect …