Greehey CCRI Archives
Bexar County Medical Society: San Antonio Medicine October 2016
October 1, 2016Cancer Research: Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis
October 1, 2016Brendan Murphy 1, Han Yin 1, John M Maris 2, E Anders Kolb 3, Richard Gorlick 4, C Patrick Reynolds 5, Min H Kang 6, Stephen T Keir 7, Raushan T Kurmasheva 8, Igor Dvorchik 9, Jianrong Wu 10, Catherine A Billups 10, Nana Boateng 10, Malcolm A Smith 11, …
Pediatric Blood & Cancer: Initial testing (stage 1) of the curaxin CBL0137 by the pediatric preclinical testing program
September 21, 2016Richard Lock 1, Hernan Carol 1, John M Maris 2, E Anders Kolb 3, Richard Gorlick 4, C Patrick Reynolds 5, Min H Kang 5, Stephen T Keir 6, Jianrong Wu 7, Andrei Purmal 8, Andrei Gudkov 9, Dias Kurmashev 10, Raushan T Kurmasheva 10, Peter J Houghton 10, …
Europe PMC: Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.
September 15, 2016Zanotto-Filho A1, Masamsetti VP1, Loranc E1, Tonapi SS1, Gorthi A1, Bernard X1, Gonçalves RM2, Moreira JC2, Chen Y1, Bishop AJ1 Abstract Alkylating agents are a commonly used cytotoxic class of anticancer drugs. Understanding the mechanisms whereby ce …
European Journal of Medicinal Chemistry: 5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells
September 14, 2016Author links open overlay panelAuthor links open overlay panelSean Henrya\, Ria Kidnera, Mary R.Reisenauera, Igor V .Magedova, Robert Kissb, Véronique Mathieub, Florence Lefrancc, Ramesh Dasarid, Antonio Evidentee, Xiaojie Yuf, Xiuye Maf, Alexander Per …
Hyundai Hope on Wheels Awards $250,000 Research Grant to Ut Health Science Center San Antonio in Honor of National Childhood Cancer Awareness Month
September 12, 2016San Antonio, TX – September 12 – Hyundai Hope On Wheels® (HHOW) and San Antonio-area Hyundai dealers will present UT Health Science Center San Antonio with a $250,000 Scholar Grant to be used to improve care and increase treatment options for kids with …
The American Journal of Pathology: Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit
September 1, 2016The conserved RNA-binding protein Musashi1 (MSI1) has been characterized as a stem cell marker, controlling the balance between self-renewal and differentiation and as a key oncogenic factor in numerous solid tumors, including glioblastoma. To explore …
UT Health SA Newsroom: Health Science Center, UTSA gain $4.6 million for cancer research
August 25, 2016The Center for Innovative Drug Discovery (CIDD), a joint program of the UT Health Science Center San Antonio and The University of Texas at San Antonio (UTSA), is receiving a $4,598,728 grant from the Cancer Prevention & Research Institute of Texas …
BMC Genomics: Detection of high variability in gene expression from single-cell RNA-seq profiling
August 22, 2016Hung-I Harry Chen, Yufang Jin, Yufei Huang & Yidong Chen Abstract Background The advancement of the next-generation sequencing technology enables mapping gene expression at the single-cell level, capable of tracking cell heterogeneity and determina …
BMC Genomics: A hierarchical model for clustering m6A methylation peaks in MeRIP-seq data
August 22, 2016Xiaodong Cui, Jia Meng, Shaowu Zhang, Manjeet K. Rao, Yidong Chen & Yufei Huang Abstract Background The recent advent of the state-of-art high throughput sequencing technology, known as Methylated RNA Immunoprecipitation combined with RNA sequencin …