Greehey CCRI News & Events Archive

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San Antonio Magazine: Top Doctors

January 1, 2020

Professor of Pediatrics, Greehey distinguished chair in genetics and cancer; division director, pediatric hematology-oncology; co-director, population science and prevention program, Mays Cancer Center/UT Health When Dr. Gail Tomlinson decided to speci …


GRACIAS Texas: Empowering South Texas’ underserved population (Tomlinson)

December 26, 2019

Senior health educator Anna Maria Pulido Saldivar, who is based in Laredo, educates community members in South Texas about cancer prevention and screening. Mays Cancer Center Annual Report Knowledge is power, and with today’s advances in science, knowi …


NATURE: Bishop lab helps discovery of R-loops in the pediatric cancer Embryonal tumors with multilayered rosettes (ETMRs)

December 18, 2019


Frontiers in Oncology: Nanoformulation of Talazoparib Increases Maximum Tolerated Doses in Combination With Temozolomide for Treatment of Ewing Sarcoma

December 17, 2019

The Pediatric Preclinical Testing Program previously identified the PARP inhibitor talazoparib (TLZ) as a means to potentiate temozolomide (TMZ) activity for the treatment of Ewing sarcoma. However, the combination of TLZ and TMZ has been toxic in both …


Technology News Network: Team Develop Drugs To Fight Leukemia and Lymphoma

December 9, 2019

UT Health San Antonio researchers, working with collaborators at the University of Florida, have discovered a safe and potent next generation of drugs to fight multiple types of leukemia and lymphoma in adults and children. The journal Nature Medicine …


BioNews Central: Leukemia, lymphoma squarely in sights of new class of drugs

December 6, 2019

UT Health San Antonio researchers, working with collaborators at the University of Florida, have discovered a safe and potent next generation of drugs to fight multiple types of leukemia and lymphoma in adults and children. The journal Nature Medicine  …


EurekAlert: Leukemia, lymphoma squarely in sights of new class of drugs

December 6, 2019

UT Health San Antonio researchers, working with collaborators at the University of Florida, have discovered a safe and potent next generation of drugs to fight multiple types of leukemia and lymphoma in adults and children. The journal Nature Medicine  …


SCITECH EUROPA: Preclinical Drug Development for Childhood Cancers

December 2, 2019


Pediatric Blood & Cancer: Phase 1/2 trial of talazoparib in combination with temozolomide in children and adolescents with refractory/recurrent solid tumors including Ewing sarcoma: A Children’s Oncology Group Phase 1 Consortium study (ADVL1411)

November 14, 2019

Abstract Purpose We conducted a phase 1/2 trial of the poly(ADP‐ribose) polymerase 1/2 inhibitor talazoparib in combination with low‐dose temozolomide (TMZ) to determine the dose‐limiting toxicities (DLTs), recommended phase 2 dose (RP2D), and pharmaco …


Nicole Hensch of the Ignatius Lab Receives The Greehey Graduate Fellowship in Children’s Health

November 13, 2019