Greehey CCRI News & Events Archive

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Oncogene: Knock-out of Hopx disrupts stemness and quiescence of hematopoietic stem cells in mice (Chen Lab)

June 12, 2020

Chien-Chin Lin, Chi-Yuan Yao, Yueh-Chwen Hsu, Hsin-An Hou, Chang-Tsu Yuan, Yi-Hung Li, Chein-Jun Kao, Po-Han Chuang, Yu-Chiao Chiu, Yidong Chen, Wen-Chien Chou & Hwei-Fang Tien Abstract HOPX is a stem cell marker in hair follicles and intestines. I …


Jove: Mass Spectrometry Analysis to Identify Ubiquitylation of EYFP-tagged CENP-A (EYFP-CENP-A)

June 10, 2020

Yohei Niikura*1, Lei Fang*2, Risa Kitagawa*3, Peizhao Li1, Yao Xi1, Ju You1, Yan Guo2, Katsumi Kitagawa3 Summary CENP-A ubiquitylation is an important requirement for CENP-A deposition at the centromere, inherited through dimerization between cell divi …


Clinical Cancer Research: Evaluation of Eribulin Combined with Irinotecan for Treatment of Pediatric Cancer Xenografts

June 1, 2020

Andrew J. Robles, Raushan T. Kurmasheva, Abhik Bandyopadhyay, Doris A. Phelps, Stephen W. Erickson, Zhao Lai, Dias Kurmashev, Yidong Chen, Malcom A. Smith, and Peter J. Houghton Abstract Purpose: Vincristine combined with camptothecin derivatives showe …


Springer Link: Genetic markers for treatment-related pancreatitis in a cohort of Hispanic children with acute lymphoblastic leukemia

May 24, 2020

Allison C. Grimes, Yidong Chen, Hima Bansal, Christine Aguilar, Luz Perez Prado, Gerardo Quezada, Jaime Estrada & Gail E. Tomlinson Abstract Purpose Treatment-related pancreatitis (TRP) is a serious complication occurring in children with acute lym …


Kunal Baxi, Ph.D. to receive Translational Science Training (TST) TL1 award. (Ignatius Lab)

May 18, 2020

The Greehey Children’s Cancer Research Institute, UT Health San Antonio wishes to congratulate Kunal Baxi, Ph.D., from the lab of Principal Investigator, Myron Ignatius, Ph.D. on receiving the UT Health San Antonio, Translational Science Training (TST) …


Nature Cell Biology: Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance

May 18, 2020

Mingjun Bi 1, Zhao Zhang 1, Yi-Zhou Jiang 2, Pengya Xue 1, Hu Wang 1, Zhao Lai 1, Xiaoyong Fu 3, Carmine De Angelis 3, Yue Gong 2, Zhen Gao 4, Jianhua Ruan 1 4, Victor X Jin 1, Elisabetta Marangoni 5, Elodie Montaudon 5, Christopher K Glass 6, Wei Li 7 …


Trauma & Acute Care Surgery: The gut microbiome distinguishes mortality in trauma patients upon admission to the emergency department

May 1, 2020

Burmeister, David M. Ph.D.; Johnson, Taylor R. BS; Lai, Zhao Ph.D.; Scroggins, Shannon R. MS; DeRosa, Mark CRT; Jonas, Rachelle B. RN; Zhu, Caroline BS; Scherer, Elizabeth MD, MPH; Stewart, Ronald M. MD, FACS; Schwacha, Martin G. Ph.D.; Jenkins, Donald …


Cell Chemical Biology: MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome

May 1, 2020

ZhiJun Qiu 1, An-Ping Lin 1, Shoulei Jiang 1, Sara M Elkashef 1, Jamie Myers 1, Subramanya Srikantan 2, Binu Sasi 1, John Z Cao 3, Lucy A Godley 3, Dinesh Rakheja 4, Yingli Lyu 5, Siyuan Zheng 6, Muniswamy Madesh 2, Yuzuru Shiio 7, Patricia L M Dahia 1 …


MDPI Cancers Magazine – Reconstruction of Ewing Sarcoma Developmental Context from Mass-Scale Transcriptomics Reveals Characteristics of EWSR1-FLI1 Permissibility (Bishop Lab)

April 16, 2020

by  Henry E. Miller 1,2, Aparna Gorthi 1,2, Nicklas Bassani 2, Liesl A. Lawrence 1,2, Brian S. Iskra 1,2 and Alexander J. R. Bishop 1,2,* This study aims at defining the features of the cell of origin for Ewing sarcoma through comparative bioinformatic …


“Singing in the Mud”, Message from the Dean

April 13, 2020

Former UT Chancellor, retired Admiral, and retired Navy Seal William H. McRaven wrote a story in the Washington Post that is worth sharing widely- “For a would-be Navy SEAL, Hell Week is the worst week of the toughest military training in the world. It …


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