Function: Constitutive mTORC1 Activation in Skeletal Muscle Increases Inflammation but is not Sufficient to Impair Glucose Tolerance (Lai Lab)
July 23, 2026Erik D. Marchant, Hanna Kalenta, Sean P. Kilroe, Jacquelyn May, Wenjun Z. Martini, Korri S. Weldon, Zhao Lai, and Blake B. Rasmussen Abstract Aberrant mechanistic target of rapamycin complex 1 (mTORC1) signaling in skeletal muscle has been implicated …
Nature Communications: Multifaceted roles of PDS5B in RAD51-dependent homology-directed DNA repair and replication fork protection (Sung Lab, Libich, Olsen, Wasmuth, Rao, et al)
July 22, 2026Jeffrey N. Katz, Lorena Samentar, Qingming Fang, Jae-Hoon Ji, Wenjing Li, Qiongmei Gao, Sahiti Kuppa, Boya Gao, Cody M. Rogers, Hardeep Kaur, Aida Badamchi Shabestari, Arijit Dutta, Shahrez Syed, Miriam Tovar, Nozomi Tomimatsu, Bipasha Mukherjee, Eliza …
Nature Structural & Molecular Biology: CST complex promotes second-strand synthesis in break-induced replication (Sung Lab, Malkova, et al)
July 21, 2026Pilendra Thakre, Jeff Wang, Liping Liu, Sameer Shah, Zhenxin Yan, Nhung Pham, Meng-Chia Tsai, Yuqin Zhao, Cody M. Rogers, Zhitong Feng, Hengyao Niu, Youngho Kwon, Xiaohua Wu, Anna Malkova, Patrick Sung & Grzegorz Ira Abstract Break-induced DNA repl …
Nature Communications: Break-induced replication forms long mutable single-strand DNA during meiosis (Malkova)
June 22, 2026Thanks to advances in treatment, more than 85% of children diagnosed with cancer now survive into adulthood. However, many survivors face long-term health challenges caused by their cancer treatments, including heart disease, diabetes, high blood press …
Greehey CCRI Researcher Awarded Grant to Advance RNA-Based Therapy for Aggressive Pediatric Brain Cancer (Penalva)
June 11, 2026Researchers at the Greehey Children’s Cancer Research Institute (Greehey CCRI) at UT Health San Antonio continue to push the boundaries of pediatric cancer research with the support of a new grant awarded by the Pediatric Cancer Foundation. Luiz O. Pen …
mBio: Identification and characterization of a SARS-CoV-2 Mpro G23 deletion ensitrelvir-resistant mutant (Gupta Lab)
June 8, 2026Yao Ma, R. Rahisuddin, Sara H. Mahmoud, Anastasija Cupic, Ahmed Magdy Khalil, Esteban Castro, Nathaniel Jackson, Mahmoud Bayoumi, Shailee Arya, Yogesh K. Gupta, Adolfo García-Sastre , Richard K. Plemper, Luis Martinez-Sobrido ABSTRACT Ensitrelvir is an …
Nature Structural & Molecular Biology: Structural insight into how RAD51 paralog exchange regulates RAD51 filament formation (Sung Lab, Hromas, Zhou, Zhao, Wasmuth, Olsen)
June 5, 2026Yashpal Rawal, Youngho Kwon, Lijia Jia, Eliza A. Ruben, Jae-Hoon Ji, Lijuan Guo, Caleb M. Stratton, Digant Nayak, Miriam Tovar, Qingming Fang, Mohd Azrin Jamalruddin, Shuo Zhou, Sahiti Kuppa, Shahrez Syed, Angela M. Jasper, Jeffrey N. Katz, Cody M. Rog …
David Libich, PhD to Receive CPRIT Grant to Study, “A Novel Approach to Targeting Ewing Sarcoma.”
REPOST: UT Health SA Newsroom Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.edu Content provided by Jane Alvarez Hernandez Principal investigator: David Libich, PhD Associate professor in the Department of Biochemistry and Structural Biology in t …
Advancing Cancer Research from the Ground Up: Introducing the Greehey CCRI Xenograft & Cell Lines Core
May 28, 2026At the Greehey Children’s Cancer Research Institute (GCCRI), groundbreaking discoveries don’t just happen in theory—they are tested, refined, and brought closer to real-world impact through cutting-edge research platforms. One of the most powerful of t …
Advancing Cancer Research: Introducing the Mouse Radiation Treatment Center (MRTC)
May 28, 2026At the Greehey Children’s Cancer Research Institute (GCCRI), breakthrough discoveries don’t happen by chance—they’re powered by innovative tools, dedicated scientists, and a commitment to translating research into better outcomes for children with canc …
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