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Translating Today's Discoveries in Childhood Cancer Research into Tomorrow's Treatments.

The Greehey Children’s Cancer Research Institute is one of only two institutes in the United States exclusively focused on pediatric cancer research. With 19 laboratories, the institute leverages expertise in cancer genomics, DNA repair, RNA biology, and drug development to discover new and less harmful treatments for childhood cancers.

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In The News

Our research expertise spans cancer genomics, DNA damage, RNA biology, and drug development. We are also expanding our focus on drug delivery, particularly through nanotechnology-based methods for delivering small RNA mimics and inhibitors.

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Top stories

Nature Communications: Highly mutagenic copying of telomeric circles promotes ALT establishment (Malkova)

Nature Structural & Molecular Biology

Nature Structural & Molecular Biology: Structural insight into how RAD51 paralog exchange regulates RAD51 filament formation (Rao, Libich, Wasmuth, Sung, Olsen et al)

Panneerdoss Subbarayalu, PhD (Rao Lab) to Receive $879,000 American Cancer Society Grant

David Libich, PhD Awarded Five‑Year, $2.1 million NIH Grant to Study “Protein Intrinsic Disorder in Genome Regulation.”

News

  • India Post: Manjeet Rao, PhD Recognized as “Indian American Cancer Scientists Honored with Prestigious SAASCR Awards for Pioneering Breakthroughs” (Rao)

    • Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

    Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

  • Recognizing Excellence in Radiation Research: Dr. Weixing Zhao Named Michael Fry Award Recipient

    • Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

    Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

  • Panneerdoss Subbarayalu, PhD (Rao Lab) to Receive $879,000 American Cancer Society Grant

    • Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

    Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

  • What if we could stop chronic pain before it starts? (Lai Lab)

    • Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

    Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

  • Nature Communications: Highly mutagenic copying of telomeric circles promotes ALT establishment (Malkova)

    • Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

    Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

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Events
Greehey CCRI Spring ’26 Seminar Series: Ratna K Vadlamudi, PhD (UTHSA)
Greehey CCRI Seminar Series: Dima Kozakov, PhD (UT Austin)

Presentation title: “Modeling and modulating disease at systems level with physics aware deep learning”
Greehey CCRI Spring ’26 Seminar Series: Reuben Harris, PhD (UTHSA)

Presentation title: “Progress on the development of novel drugs for viral proteases”
Greehey CCRI Seminar Series: Lingtao Jin, PhD (UTHSA)

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