Our research expertise spans cancer genomics, DNA damage, RNA biology, and drug development. We are also expanding our focus on drug delivery, particularly through nanotechnology-based methods for delivering small RNA mimics and inhibitors.
News
- Science Advances: Ligand-receptor interactions induce and mediate regulatory functions of BATF3+ B cells (Chen Lab, Zheng Lab)
- ACS Medicinal Chemistry Letters: Identification and Exploration of a Series of SARS-Cov-2 MPro Cyano-Based Inhibitors Revealing Ortho-Substitution Effects within the P3 Biphenyl Group (Olsen)
- Molecular Medicine: Selective inhibition of BRAF and CRAF sensitizes NF1-deficient malignant peripheral nerve sheath tumors to MEK inhibitors (Zheng, Kitagawa Lab)
- Nature Structural & Molecular Biology: Cryo-EM structures reveal the molecular mechanism of SUMO E1–E2 thioester transfer (Olsen Lab, Sung Lab)
- BioRxiv: Phosphoregulation of RAD51AP1 function in homology-directed repair (Sung Lab)
Events
Greehey CCRI Seminar Series – Fall ’25: Manjeet Rao, PhD (UT San Antonio)
Presentation title: Disrupting Astrocyte–Tumor Crosstalk to Target Metabolic Vulnerabilities in Medulloblastoma
4th Annual Gear Up Against Kids Cancer Bike Ride
We’re excited to announce that the 4th Annual Gear Up Against Kids Cancer has been rescheduled for Saturday, October 18, 2025, at a new location: Floresville City Park (756 TX-97, Floresville, TX 78114), right next to the Event Center.
Greehey CCRI Seminar Series – Fall ’25: Xiaoyu Xue, PhD (Texas State)
Presentation Title: Mechanism of Smc5/6-Mediated Protein Sumoylation in DNA Repair