Our research expertise spans cancer genomics, DNA damage, RNA biology, and drug development. We are also expanding our focus on drug delivery, particularly through nanotechnology-based methods for delivering small RNA mimics and inhibitors.
News
- Nature Structural & Molecular Biology: Cryo-EM structures reveal the molecular mechanism of SUMO E1–E2 thioester transfer (Olsen Lab, Sung Lab)
- BioRxiv: Phosphoregulation of RAD51AP1 function in homology-directed repair (Sung Lab)
- Protein Science: Molecular basis of EWS interdomain self-association and its role in condensate formation (Libich Lab)
- Trends in Biochemical Sciences: E3 Ubiquitin Ligases in Signaling, Disease, and Therapeutics (Olsen)
- Aging Cell: Inhibition of Hippo Signaling Through Ablation of Lats1 and Lats2 Protects Against Cognitive Decline in 5xFAD Mice via Increasing Neuronal Resilience Against Ferroptosis (Zheng)
Events
Greehey CCRI Seminar Series – Fall ’25: Hardeep Kaur, PhD (UT-San Antonio)
Presentation title: “Regulation of Double-Strand Repair Pathway Choice
Greehey CCRI Seminar Series – Fall ’25: Yatin M. Vyas, MBBS (Penn State Health)
Presentation Title: DNA to Disease: Wiskott–Aldrich Syndrome and Fanconi Anemia Pathway Crosstalk in Genome Protection and Cancer Prevention
Greehey CCRI Seminar Series – Fall ’25: Manjeet Rao, PhD (UT San Antonio)
Presentation title: Disrupting Astrocyte–Tumor Crosstalk to Target Metabolic Vulnerabilities in Medulloblastoma
4th Annual Gear Up Against Kids Cancer Bike Ride
We’re excited to announce that the 4th Annual Gear Up Against Kids Cancer has been rescheduled for Saturday, October 18, 2025, at a new location: Floresville City Park (756 TX-97, Floresville, TX 78114), right next to the Event Center.