Our research expertise spans cancer genomics, DNA damage, RNA biology, and drug development. We are also expanding our focus on drug delivery, particularly through nanotechnology-based methods for delivering small RNA mimics and inhibitors.
News
- Cancers: Biological Advances and Current Challenges for Pediatric Rhabdomyosarcoma (Houghton, Ignatius, et al)
- BioRxiv: Diverse Mechanisms of SMARCB1 Inactivation and Genome Maintenance Defects in Ultra-Rare Malignant Rhabdoid Tumors (Kurmasheva Lab, Chen, Lai)
- BioRxiv: Intrinsically disordered SERBP1 regulates translation through topology-driven G-quadruplex recognition (Libich Lab)
- iScience: Predicting and interpreting protein and phosphoprotein abundance from pan-cancer and single-cell transcriptomes (Chen Lab)
- Nature Communications: Cryo-EM structures of UBA6 reveal mechanisms of E1–E2 specificity and dual FAT10/ubiquitin thioester transfer (Olsen, Wasmuth, Sung,)
Events
Greehey CCRI Seminar Series: Wenshe Ray Liu, PhD (TX A&M)
Presentation title: “Targeting YEATS – An Epigenetic Reader Domain for Anti-Cancer Drug Discovery.”
5th Annual Gear Up Against Kids Cancer Bike Ride
Signing up for the 5th Annual Gear Up Against Kids Cancer bike ride is a powerful way to support local childhood cancer research and turn your passion for cycling into a meaningful impact. Every dollar you raise helps fund essential research projects at the Greehey Children’s Cancer Research Institute – UT Health San Antonio, driving innovative studies and treatments that benefit children in our community fighting cancer.