Drug Target Review: Why PARP inhibitors fail: key role of the CST complex in BRCA1-deficient cancers (Sung)

April 8, 2026

 Scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio), in collaboration with Dana-Farber Cancer Institute at Harvard Medical School, Columbia University and Irving Medical Center, have made a critical breakthrough in understanding why cancers with BRCA1 mutations become resistant to a widely used class of drugs known as PARP inhibitors - pharmacological inhibitors of poly [...]

Congratulations to Elizabeth Wasmuth, PhD on Her UT Health SA Presidential Excellence Award

February 27, 2026

 We are proud to celebrate Elizabeth V. Wasmuth, PhD, Assistant Professor and Howard Hughes Medical Institute Freeman Hrabowski Scholar in the Department of Biochemistry and Structural Biology, Long School of Medicine, for her outstanding achievements and recognition through the 2026 UT Health San Antonio Presidential Excellence Awards. Every day, our employees work tirelessly to advance [...]

🎉Congratulations to Chris Do (Rao Lab) for being named the UT Health San Antonio Graduate School of Biomedical Sciences Sr. Student of the Year!

August 12, 2025

 The GSBS Senior Student of the Year Award recognizes a graduate student who demonstrates the best potential for research success as measured by publications, presentations, and awards. The student must demonstrate sustained excellence in academics. Chris Do is an MD/PhD student in the South Texas Medical Scientist Training Program (STX-MSTP). Chris is a doctoral candidate [...]
Chris Do GSBS Senior Student of the Year

KENS5 & Great Day SA, Hyundai Hope on Wheels Handprint Ceremony (Tomlinson)

August 11, 2025

 Gail Tomlinson, MD, PhD, professor of pediatrics and division chief of pediatric hematology-oncology in the Department of Pediatrics at UT Health San Antonio, was interviewed by KENS-TV and appeared on the station’s morning show, “Great Day SA.” Dr. Tomlinson spoke about Hyundai Hope on Wheels® and the organization’s support for pediatric cancer research. Together with Dr. [...]

UT Health San Antonio scientists uncover how some cancers outsmart immune system (Rao, Sung, Zheng, & Chen Labs)

July 17, 2025

 Shared By: Claire Kowalick July 17, 2025 FOXM1 protein identified as key driver in immunotherapy resistance, unlocking new therapeutic avenues   For years, scientists have found the overexpression of a specific protein called FOXM1 in a wide range of cancers, including ovarian, breast, and pediatric cancers. A recent study by scientists at The University of Texas [...]

Texas Public Radio: Science & Medicine: Sabotaging the molecular engines of some pediatric cancers (Gupta)

February 24, 2025

 Ewing sarcoma and rhabdomyosarcoma are cancers that overwhelmingly impact children. They're soft tissue cancers that are thankfully rare because treatment options are limited, according to pediatric cancer researcher Yogesh Gupta, PhD, an associate professor at Greehey Children's Cancer Research Institute at UT Health San Antonio. “The drug treatment regimen has not been changed in the last three decades,” [...]

Kurmasheva Lab is Featured in CPRIT Annual Report

February 6, 2025

 Doctors diagnose nearly 1,200 Texans under 20 years of age with cancer every year. Despite intensive genotoxic therapy, nearly 20% of these children will die from their cancer. Those who survive face a lifetime of potential toxicities due to their therapy. CPRIT awarded a $4 million grant to The University of Texas Health Science Center [...]