Clinical Cancer Research: Preclinical Activity of the B7-H3-Targeting Antibody Drug Conjugate (ADC) Vobramitamab Duocarmazine (Vobra Duo) in Pediatric Cancer Solid Tumors (Chen, Houghton, Kurmasheva Lab)
April 22, 2026Edward Favours Haiying Tang Peyton Wong Samuel Ghilu Vanessa del Pozo Elena Mironova Yidong Chen Tim Stearns Steven Neuhauser Eric J. Earley Stephen W. Erickson Jee Young Kwon Emily L. Jocoy David Groff Kateryna Krytska Matthew Tsang Be …
BioRxiv: Diverse Mechanisms of SMARCB1 Inactivation and Genome Maintenance Defects in Ultra-Rare Malignant Rhabdoid Tumors (Kurmasheva Lab, Chen, Lai)
March 27, 2026Elizabeth Rasmussen, Elena Mironova, Zhao Lai, Kendra Maaß, Stefanie Volz, Dias Kurmashev, Stefan M. Pfister, Yidong Chen, Raushan T. Kurmasheva ABSTRACT Malignant rhabdoid tumors (MRTs) are extremely rare and highly aggressive pediatric cancers classi …
Dr. Raushan Kurmasheva’s laboratory has been awarded a $400K NCI SBIR Phase II grant titled “Enhanced overall survival in high-risk pediatric tumors using a novel oral small molecule.”
January 7, 2026Federal Awarding Agency: NIH/NCI Project Title: Enhanced overall survival in high-risk pediatric tumors using a novel oral small molecule. Sub PI: Raushan Kurmasheva, PhD Start: 9/15/25 End: 9/14/27 Amount: $401,844 Project Summary: The research in thi …
BioRxiv: Robust statistical assessment of Oncogenotype to Organotropism translation in xenografted zebrafish (Kurmasheva, et al)
June 24, 2025Abstract Organotropism results from the functional versatility of metastatic cancer cells to survive and proliferate in diverse microenvironments. This adaptivity can originate in clonal variation of the spreading tumor and is often empowered by epigen …
Raushan Kurmasheva, PhD, was awarded the Translation to Cure (T2C) Award by the CURE Childhood Cancer foundation
June 16, 2025A cancer diagnosis is always devastating and is especially overwhelming when the patient is a child. This is why the CURE Childhood Cancer Foundation is on a mission to advance research that will bring an end to childhood cancers. The foundation priori …
NPJ – Precision Oncology: Benchmarking mouse contamination removing protocols in patient-derived xenografts genomic profiling (Zheng, Wang, Kurmasheva, Houghton, Lai, & Chen Labs)
April 17, 2025Mukund Bhandari, Funan He, Anna Rogojina, Fuyang Li, Yi Zou, Jing Jiang, Zhao Lai, Peter Houghton, Raushan T. Kurmasheva, Yidong Chen, Xiaojing Wang & Siyuan Zheng Abstract Patient-derived xenograft (PDX) models are widely used in cancer research. …
Kurmasheva Lab is Featured in CPRIT Annual Report
February 6, 2025Doctors diagnose nearly 1,200 Texans under 20 years of age with cancer every year. Despite intensive genotoxic therapy, nearly 20% of these children will die from their cancer. Those who survive face a lifetime of potential toxicities due to their ther …
Pharmacology & Therapeutics: Lessons learned from 20 years of preclinical testing in pediatric cancers (Houghton, Kurmasheva)
November 11, 2024Malcolm A. Smith a, Peter J. Houghton b, Richard B. Lock c, John M. Maris d, Richard Gorlick e, Raushan T. Kurmasheva b, Xiao-Nan Li f, Beverly A. Teicher a, Jeffrey H. Chuang g, Filemon S. Dela Cruz h, Michael A. Dyer i, Andrew L. Kung h, Michael W. L …
MDPI Cancers: Synergistic Antitumor Activity of Talazoparib and Temozolomide in Malignant Rhabdoid Tumors (Kurmasheva, Lai, & Chen)
June 18, 2024Elena Mironova, Sebastian Molinas, Vanessa Del Pozo, Abhik M. Bandyopadhyay, Zhao Lai, Dias Kurmashev, Eric L. Schneider, Daniel V. Santi, Yidong Chen, Raushan T. Kurmasheva Simple Summary Mutation of the SMARCB1 gene can cause one …
IScience: Comprehensive Characterization of Patient-Derived Xenograft Models of Pediatric Leukemia (Houghton, Grimes, Lai, Chen, Zheng, Kurmasheva, & Tomlinson Labs)
December 6, 2023Anna Rogojina 1 12, Laura, J. Klesse 2 3 4 12, Erin Butler 2 3 4 12, Jiwoong Kim 5, He Zhang 5, Xue Xiao 5, Lei Guo 5, Qinbo Zhou 5, Taylor Hartshorne 2, Dawn Garcia 1, Korri Weldon 1, Trevor Holland 1, Abhik Bandyopadhyay 1, Luz Perez Prado 1, Shidan …
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