Cell Reports: IGSF10 is a RET antagonist regulating Ewing sarcoma growth and GnRH neuron migration (Chen, Houghton, & Shiio Lab)
July 24, 2025Panneerselvam Jayabal1 ∙ Xiuye Ma1 ∙ Maleeha Akram2 ∙ Hannah Bow2 ∙ Pranay Mandal2 ∙ Naira Mansano2 ∙ Yidong Chen1,3,4 ∙ Susan T. Weintraub4,5 ∙ Peter J. Houghton1,4,6 ∙ Susan Wray2 ∙ Yuzuru Shiio Highlights Ewing sarcoma depends on IGSF10, which inhib …
Cell Reports: Ceramide-induced cleavage of GPR64 intracellular domain drives Ewing sarcoma (Chen, Houghton, & Shiio Labs)
July 19, 2024Kruthi Suvarna Panneerselvam Jayabal Xiuye Ma Hu Wang Yidong Chen Susan T. Weintraub Xianlin Han Peter J. Houghton Yuzuru Shiio 8 Highlights Ewing sarcoma depends on secreted SMPD1, a ceramide-generating enzyme, and ceramide GPR64 responds to ce …
Genes & Cancer: Roles of USP1 in Ewing sarcoma (Shiio Lab)
February 13, 2024Panneerselvam Jayabal1, Xiuye Ma1 and Yuzuru Shiio1,2,3 ABSTRACT Ewing sarcoma is a cancer of bone and soft tissue in children and young adults that is driven by the EWS-ETS fusion transcription factor, most commonly EWS-FLI1. We previously reported th …
Cell Reports: Nitric Oxide Suppression by Secreted Frizzled-Related Protein 2 Drives Retinoblastoma (Shiio & Houghton Labs)
March 17, 2023Panneerselvam Jayabal 1, Fuchun Zhou 1, Xiuye Ma 1, Kathryn M. Bondra 1, Barron Blackman 1, Susan T. Weintraub 2 3, Yidong Chen 1 3 4, Patricia Chévez-Barrios 5, Peter J. Houghton 1 3 6, Brenda Gallie 7, Yuzuru Shiio 1 2 3 8 Highlights The autocrine si …
Genes & Cancer: Slit2 signaling stimulates Ewing sarcoma growth (Shiio Lab)
December 19, 2022Kruthi Suvarna1, Panneerselvam Jayabal1, Xiuye Ma1 and Yuzuru Shiio1,2,3 1 Greehey Children’s Cancer Research Institute, The University of Texas Health Science Center, San Antonio, TX 78229-3900, USA 2 Cancer Therapy and Research Center, The University …
Genes & Cancer: EZH2 suppresses endogenous retroviruses and an interferon response in cancers (Shiio Lab)
January 10, 2022Panneerselvam Jayabal1, Xiuye Ma1 and Yuzuru Shiio1,2,3 ABSTRACT Ewing sarcoma is an aggressive cancer of the bone and soft tissue in children. It is characterized by the chromosomal translocation between EWS and an Ets family transcription factor, mos …
eLife Sciences: Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness (Shiio Lab)
July 9, 2021Haritha Mathsyaraja, Jonathen Catchpole, Brian Freie, Emily Eastwood, Ekaterina Babaeva, Michael Geuenich, Pei Feng Cheng, Jessica Ayers, Ming Yu, Nan Wu, Sitapriya Moorthi, Kumud R Poudel, Amanda Koehne, William Grady, A Mc …
Cell Reports: NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growthNELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth (Shiio, Houghton)
July 8, 2021Panneerselvam Jayabal1, Fuchun Zhou1, Xiufen Lei1, XiuyeMa1, Barron Blackman1, Susan T.Weintraub23, Peter J.Houghton134, YuzuruShiio1235 Highlights • The autocrine signaling mediated by NELL2 maintains Ewing sarcoma cell growth • NELL2 signaling inhibi …
Cell Reports: GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
November 3, 2020Fuchun Zhou (1), David J.Elzi (1, 2), Panneerselvam Jayabal(1), Xiuye Ma(1), Yu-Chiao Chiu (1) Yidong Chen 1,3,4) Barron Blackman(1) Susan T.Weintraub (4, 5) Peter J.Houghton 1,4,6) Yuzuru Shiio (1,4,5,7) Highlights The autocrine signaling mediated by …
Cell Chemical Biology: MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome
May 1, 2020ZhiJun Qiu 1, An-Ping Lin 1, Shoulei Jiang 1, Sara M Elkashef 1, Jamie Myers 1, Subramanya Srikantan 2, Binu Sasi 1, John Z Cao 3, Lucy A Godley 3, Dinesh Rakheja 4, Yingli Lyu 5, Siyuan Zheng 6, Muniswamy Madesh 2, Yuzuru Shiio 7, Patricia L M Dahia 1 …
-
Page 1 out of 2
- Next